Ligand name: N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide
PDB ligand accession: 032
DrugBank: DB08881
PubChem: 42611257
ChEMBL: CHEMBL1229517
InChI Key: GPXBXXGIAQBQNI-UHFFFAOYSA-N
SMILES: CCCS(=O)(=O)Nc1ccc(c(c1F)C(=O)c2c[nH]c3c2cc(cn3)c4ccc(cc4)Cl)F

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organic oxygen compounds
    • Class: Organooxygen compounds
      • Subclass: Carbonyl compounds

List of proteins that are targets for 032

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P15056_032	P15056	Serine/threonine-protein kinase B-raf	inhibitor	IC50(nM) = 4.0 Kd(nM) = 10.0 EC50(nM) = 601.0
2	Q9NYL2_032	Q9NYL2	Mitogen-activated protein kinase	n/a	IC50(nM) = 4.0
3	Q5IBP5_032	Q5IBP5	AKAP9-BRAF fusion protein	n/a