Ligand name: 3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1~{H}-benzimidazol-2-one
PDB ligand accession: 1II
DrugBank: DB01100
PubChem: 16362
ChEMBL: CHEMBL1423
InChI Key: YVUQSNJEYSNKRX-UHFFFAOYSA-N
SMILES: c1ccc2c(c1)NC(=O)N2C3CCN(CC3)CCCC(c4ccc(cc4)F)c5ccc(cc5)F

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Diphenylmethanes

List of proteins that are targets for 1II

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	Q9P0X4_1II	Q9P0X4	Voltage-dependent T-type calcium	n/a
2	P35462_1II	P35462	D(3) dopamine receptor	antagonist	Ki(nM) = 0.2
3	Q12809_1II	Q12809	Voltage-gated inwardly rectifying	inhibitor	Ki(nM) = 18.0 IC50(nM) = 3.02
4	C6XGT2_1II	C6XGT2	Putative amino acid-binding	n/a
5	P0DP23_1II	P0DP23	Calmodulin-1	inhibitor
6	P14416_1II	P14416	D(2) dopamine receptor	antagonist	Ki(nM) = 0.39