Ligand name: Nortriptyline
PDB ligand accession: 21B
DrugBank: DB00540
PubChem: 4543
ChEMBL: CHEMBL445
InChI Key: PHVGLTMQBUFIQQ-UHFFFAOYSA-N
SMILES: CNCCC=C1c2ccccc2CCc3c1cccc3

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Dibenzocycloheptenes
      • Subclass: None

List of proteins that are targets for 21B

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	Q9NB97_21B	Q9NB97	n/a
2	P25100_21B	P25100	antagonist
3	P28223_21B	P28223	antagonist
4	P31645_21B	P31645	inhibitor	Ki(nM) = 15.0
5	P14416_21B	P14416	antagonist	Ki(nM) = 2570.0
6	P28335_21B	P28335	antagonist	Ki(nM) = 41.0
7	P35367_21B	P35367	antagonist	Ki(nM) = 6.3
8	P08908_21B	P08908	antagonist	Ki(nM) = 294.0
9	P23975_21B	P23975	inhibitor	Ki(nM) = 1.49
10	P35368_21B	P35368	antagonist
11	P35348_21B	P35348	antagonist	Ki(nM) = 55.0