Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide
PDB ligand accession: 2BA
DrugBank: n/a
PubChem: 11158091
ChEMBL: CHEMBL1229884
InChI Key: PDXMFTWFFKBFIN-XPWFQUROSA-N
SMILES: c1nc(c2c(n1)n(cn2)C3C(C4C(O3)COP(=O)(OC5C(COP(=O)(O4)O)OC(C5O)n6cnc7c6ncnc7N)O)O)N

ClassyFire chemical classification:

List of proteins that are targets for 2BA

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 A0A0U1MUE2_2BA A0A0U1MUE2 Cyclic-di-AMP phosphodiesterase (EC n/a
2 O31698_2BA O31698 Cyclic di-AMP receptor n/a
3 A0A0R2NIU5_2BA A0A0R2NIU5 Quaternary amine transport n/a
4 A0A167RS01_2BA A0A167RS01 deleted n/a
5 W8TQN9_2BA W8TQN9 Monovalent cation antiporter-2 n/a
6 Q5HIJ4_2BA Q5HIJ4 deleted n/a
7 A7SLZ2_2BA A7SLZ2 Stimulator of interferon n/a
8 Q9KHT9_2BA Q9KHT9 Carnitine transport ATP-binding n/a
9 A0A077VS08_2BA A0A077VS08 deleted n/a
10 Q54A37_2BA Q54A37 Dihydrodiol dehydrogenase n/a
11 J9USJ9_2BA J9USJ9 deleted n/a
12 Q86WV6_2BA Q86WV6 Stimulator of interferon n/a
13 B8XX90_2BA B8XX90 Stimulator of interferon n/a
14 P37538_2BA P37538 Cyclic di-AMP receptor n/a
15 K0JNC6_2BA K0JNC6 GntR family transcriptional n/a
16 Q99WC0_2BA Q99WC0 deleted n/a
17 Q8Y746_2BA Q8Y746 Lmo1466 protein n/a
18 A0A1D2IWV8_2BA A0A1D2IWV8 CBS domain-containing protein n/a
19 W6G6F5_2BA W6G6F5 deleted n/a
20 A0A164SLA6_2BA A0A164SLA6 deleted n/a
21 Q9WY43_2BA Q9WY43 DNA integrity scanning n/a
22 Q3TBT3_2BA Q3TBT3 Stimulator of interferon n/a
23 A0A089XIW4_2BA A0A089XIW4 deleted n/a
24 P41440_2BA P41440 Reduced folate transporter n/a
25 A0A2R3XZB7_2BA A0A2R3XZB7 Stimulator of interferon n/a
26 A0A076YWK5_2BA A0A076YWK5 CBS domain-containing protein n/a
27 P73954_2BA P73954 Membrane-associated protein slr1513 n/a
28 Q8Y5E4_2BA Q8Y5E4 Diadenylate cyclase (DAC) n/a
29 Q8Y3Y7_2BA Q8Y3Y7 Lmo2692 protein n/a