Ligand name: (2R)-2-hydroxypentanedioic acid
PDB ligand accession: 2HG
DrugBank: n/a
PubChem: 439391
ChEMBL: CHEMBL1614745
InChI Key: HWXBTNAVRSUOJR-GSVOUGTGSA-N
SMILES: C(CC(=O)O)C(C(=O)O)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organic acids and derivatives
    • Class: Hydroxy acids and derivatives
      • Subclass: Short-chain hydroxy acids and derivatives

List of proteins that are targets for 2HG

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	Q9GYI0_2HG	Q9GYI0	Lysine-specific demethylase 7	n/a
2	O14607_2HG	O14607	Histone demethylase UTY	n/a
3	O75164_2HG	O75164	Lysine-specific demethylase 4A	n/a
4	Q12797_2HG	Q12797	Aspartyl/asparaginyl beta-hydroxylase (EC	n/a
5	Q8N465_2HG	Q8N465	D-2-hydroxyglutarate dehydrogenase, mitochondrial	n/a
6	Q9NWT6_2HG	Q9NWT6	Hypoxia-inducible factor 1-alpha	n/a
7	Q8N371_2HG	Q8N371	Bifunctional peptidase and	n/a