Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: ACETYL COENZYME *A
PDB ligand accession: ACO
DrugBank: n/a
PubChem: 444493
ChEMBL: CHEMBL1230809
InChI Key: ZSLZBFCDCINBPY-ZSJPKINUSA-N
SMILES: CC(=O)SCCNC(=O)CCNC(=O)C(C(C)(C)COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)n2cnc3c2ncnc3N)O)OP(=O)(O)O)O

ClassyFire chemical classification:

List of proteins that are targets for ACO

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q81P86_ACO Q81P86 Aminoglycoside N(3)-acetyltransferase (EC n/a
2 O06543_ACO O06543 Alpha-methylacyl-CoA racemase (AMACR) n/a
3 Q4WCL5_ACO Q4WCL5 Acetyl-CoA acetyltransferase erg10B, n/a
4 Q9M6U3_ACO Q9M6U3 Hydroxymethylglutaryl-CoA synthase (HMG-CoA n/a
5 A0A0H3AQB6_ACO A0A0H3AQB6 Phosphinothricin N-acetyltransferase (EC n/a
6 D2PVF8_ACO D2PVF8 GCN5-related N-acetyltransferase n/a
7 A0R3G9_ACO A0R3G9 [ribosomal protein uS5]-alanine n/a
8 Q27198_ACO Q27198 Histone acetyltransferase GCN5 n/a
9 Q0ZQ43_ACO Q0ZQ43 CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate acetyltransferase (EC n/a
10 A0A0S4VB05_ACO A0A0S4VB05 PopP2 protein n/a
11 A4YDF6_ACO A4YDF6 Citrate synthase (EC n/a
12 Q96F10_ACO Q96F10 Thialysine N-epsilon-acetyltransferase (EC n/a
13 Q8KRB5_ACO Q8KRB5 Acetyltransferase GNAT family n/a
14 Q820T1_ACO Q820T1 Beta-ketoacyl-[acyl-carrier-protein] synthase III n/a
15 Q5AAJ8_ACO Q5AAJ8 Histone acetyltransferase RTT109 n/a
16 A0A2L1TND5_ACO A0A2L1TND5 Putative Acyl-transferase domain n/a
17 Q9HL57_ACO Q9HL57 Spermidine N(1)-acetyltransferase (SAT) n/a
18 P41227_ACO P41227 N-alpha-acetyltransferase 10 (EC n/a
19 Q97MN4_ACO Q97MN4 Predicted acetyltransferase n/a
20 P43572_ACO P43572 Enhancer of polycomb-like n/a
21 Q5SJ05_ACO Q5SJ05 Probable acetyltransferase n/a
22 Q93S40_ACO Q93S40 Polysialic acid O-acetyltransferase n/a
23 Q97NS4_ACO Q97NS4 deleted n/a
24 Q47510_ACO Q47510 MccE protein n/a
25 C4IR59_ACO C4IR59 deleted n/a
26 A0A3A1BNP8_ACO A0A3A1BNP8 deleted n/a
27 B1MJN9_ACO B1MJN9 Acetyltransferase, GNAT n/a
28 Q9HV14_ACO Q9HV14 N-acetyltransferase domain-containing protein n/a
29 Q97R46_ACO Q97R46 Bifunctional protein GlmU n/a
30 Q12341_ACO Q12341 Histone acetyltransferase type n/a
31 Q6PH17_ACO Q6PH17 Alpha-tubulin N-acetyltransferase 1 n/a
32 A0A334FGR6_ACO A0A334FGR6 VioB n/a
33 A0A3A5LTU8_ACO A0A3A5LTU8 Pyruvate carboxylase (EC n/a
34 Q92830_ACO Q92830 Histone acetyltransferase KAT2A n/a
35 Q8UD38_ACO Q8UD38 deleted n/a
36 P23007_ACO P23007 Citrate synthase, mitochondrial n/a
37 K0HK73_ACO K0HK73 deleted n/a
38 Q6NLS5_ACO Q6NLS5 N-alpha-acetyltransferase 60 (EC n/a
39 Q97ML2_ACO Q97ML2 Predicted acetyltransferase n/a
40 P50870_ACO P50870 Streptogramin A acetyltransferase n/a
41 P11498_ACO P11498 Pyruvate carboxylase, mitochondrial n/a
42 Q9W469_ACO Q9W469 Agmatine N-acetyltransferase (EC n/a
43 P07464_ACO P07464 Galactoside O-acetyltransferase (GAT) n/a
44 P13249_ACO P13249 Puromycin N-acetyltransferase (EC n/a
45 O69762_ACO O69762 Hydroxycinnamoyl-CoA hydratase-lyase (HCHL) n/a
46 A0A0J5HSJ5_ACO A0A0J5HSJ5 Acetyltransferase (N-acetyltransferase) (Putative n/a
47 O59596_ACO O59596 N-acetyltransferase domain-containing protein n/a
48 P28793_ACO P28793 Fatty acid oxidation n/a
49 D4GTL2_ACO D4GTL2 Malate synthase (MSH) n/a
50 Q5FAE1_ACO Q5FAE1 UDP-N-acetylgalactosaminyltransferase n/a
51 A5U161_ACO A5U161 Bifunctional protein GlmU n/a
52 Q65LG7_ACO Q65LG7 Probable acetyltransferase n/a
53 Q9LFM3_ACO Q9LFM3 Acyl-CoA N-acyltransferases (NAT) n/a
54 Q92794_ACO Q92794 Histone acetyltransferase KAT6A n/a
55 P26839_ACO P26839 Virginiamycin A acetyltransferase n/a
56 Q4WCU5_ACO Q4WCU5 Glucosamine 6-phosphate N-acetyltransferase n/a
57 A4YGX6_ACO A4YGX6 Citrate synthase (EC n/a
58 P96382_ACO P96382 Bifunctional protein GlmU n/a
59 A0A418LDP6_ACO A0A418LDP6 GNAT family N-acetyltransferase n/a
60 Q9DBL7_ACO Q9DBL7 Bifunctional coenzyme A n/a
61 Q9AJC4_ACO Q9AJC4 ATP-citrate lyase alpha-subunit n/a
62 P43577_ACO P43577 Glucosamine 6-phosphate N-acetyltransferase n/a
63 Q9KLB0_ACO Q9KLB0 Hexapeptide-repeat containing-acetyltransferase n/a
64 Q6DNF2_ACO Q6DNF2 CurA n/a
65 Q86UY6_ACO Q86UY6 N-alpha-acetyltransferase 40 (EC n/a
66 A0A0D6I609_ACO A0A0D6I609 GCN5 family acetyltransferase n/a
67 O74985_ACO O74985 N-terminal acetyltransferase A n/a
68 J7QA90_ACO J7QA90 DUF1778 domain-containing protein n/a
69 Q8VJU4_ACO Q8VJU4 Isocitrate lyase 2 n/a
70 Q97CT7_ACO Q97CT7 N-terminal acetyltransferase complex n/a
71 Q9KL03_ACO Q9KL03 Spermidine N(1)-acetyltransferase (SAT) n/a
72 Q5HD32_ACO Q5HD32 deleted n/a
73 A0A1V3CQ74_ACO A0A1V3CQ74 deleted n/a
74 A0A0D6HSU7_ACO A0A0D6HSU7 GNAT family N-acetyltransferase n/a
75 Q81N16_ACO Q81N16 Maltose O-acetyltransferase (EC n/a
76 Q08689_ACO Q08689 N-alpha-acetyltransferase NAT5 (NatA n/a
77 Q5SQI0_ACO Q5SQI0 Alpha-tubulin N-acetyltransferase 1 n/a
78 Q1EMV2_ACO Q1EMV2 Fluoroacetyl-CoA thioesterase (EC n/a
79 A3LHH1_ACO A3LHH1 deleted n/a
80 Q6MM14_ACO Q6MM14 NADP-dependent malate dehydrogenase n/a
81 Q6TFC6_ACO Q6TFC6 QdtC n/a
82 Q9H999_ACO Q9H999 Pantothenate kinase 3 n/a
83 Q52424_ACO Q52424 Aminoglycoside 2'-N-acetyltransferase (EC n/a
84 P76562_ACO P76562 tRNA(Met) cytidine acetyltransferase n/a
85 Q06592_ACO Q06592 Histone acetyltransferase HPA2 n/a
86 O33289_ACO O33289 Amino-acid acetyltransferase (EC n/a
87 Q3V1Y3_ACO Q3V1Y3 Carnitine O-acetyltransferase (Carnitine n/a
88 O05581_ACO O05581 Acetyltransferase Pat (EC n/a
89 A0A385EXR5_ACO A0A385EXR5 N-acetyltransferase domain-containing protein n/a
90 Q9H7X0_ACO Q9H7X0 N-alpha-acetyltransferase 60 (hNaa60) n/a
91 Q5SLW7_ACO Q5SLW7 Probable acetyltransferase n/a
92 O14929_ACO O14929 Histone acetyltransferase type n/a
93 Q5CPU3_ACO Q5CPU3 Diamine acetyltransferase (EC n/a
94 Q6MM15_ACO Q6MM15 Malate dehydrogenase (EC n/a
95 Q6SJ71_ACO Q6SJ71 AAC(6')-Ib (AAC(6')-Ib-cr aminoglycoside n/a
96 Q5C8M4_ACO Q5C8M4 GNAT family N-acetyltransferase n/a
97 O86785_ACO O86785 Holo-[acyl-carrier-protein] synthase (Holo-ACP n/a
98 P71727_ACO P71727 N-acetyltransferase Eis (EC n/a
99 B2HSY2_ACO B2HSY2 Malate synthase G n/a
100 Q9H7Z6_ACO Q9H7Z6 Histone acetyltransferase KAT8 n/a
101 Q8FBQ3_ACO Q8FBQ3 dTDP-fucosamine acetyltransferase (EC n/a
102 Q5FAK7_ACO Q5FAK7 Amino-acid acetyltransferase (EC n/a
103 Q9X024_ACO Q9X024 Bifunctional NAD(P)H-hydrate repair n/a
104 Q8ZJW4_ACO Q8ZJW4 [Ribosomal protein bS18]-alanine n/a
105 Q8NRC3_ACO Q8NRC3 2-oxoglutarate dehydrogenase E1/E2 n/a
106 Q1QD33_ACO Q1QD33 Acetyl transferase protein n/a
107 P0AFI0_ACO P0AFI0 Oxalyl-CoA decarboxylase (EC n/a
108 P16966_ACO P16966 Acetyltransferase (EC 2.3.1.-) n/a
109 A0A081LU80_ACO A0A081LU80 N-acetyltransferase (GNAT family n/a
110 Q47030_ACO Q47030 Aminoglycoside N(3)-acetyltransferase (EC n/a
111 A9IH93_ACO A9IH93 Lipopolysaccharides biosynthesis acetyltransferase n/a
112 Q8MKK2_ACO Q8MKK2 Arylalkylamine N-acetyltransferase 1 n/a
113 Q9GZZ1_ACO Q9GZZ1 N-alpha-acetyltransferase 50 (hNaa50p) n/a
114 Q5KQI6_ACO Q5KQI6 Serotonin N-acetyltransferase 1, n/a
115 Q8F3Q1_ACO Q8F3Q1 (R)-citramalate synthase CimA n/a
116 A0A0U2B867_ACO A0A0U2B867 deleted n/a
117 Q0P9D1_ACO Q0P9D1 UDP-N-acetylbacillosamine N-acetyltransferase (EC n/a
118 Q07794_ACO Q07794 Histone acetyltransferase RTT109 n/a
119 V9M3A9_ACO V9M3A9 N-acetyl-beta-D glucosaminidase (EC n/a
120 A0A2K1KKM6_ACO A0A2K1KKM6 N-acetyltransferase domain-containing protein n/a
121 Q9UTI3_ACO Q9UTI3 N-terminal acetyltransferase A n/a
122 Q2CEE2_ACO Q2CEE2 Putative acetyltransferase OgpAT n/a
123 A0A1T3E2H1_ACO A0A1T3E2H1 deleted n/a
124 P37330_ACO P37330 Malate synthase G n/a
125 Q47NQ8_ACO Q47NQ8 Enoyl-CoA hydratase (EC n/a
126 A0R2B1_ACO A0R2B1 Multifunctional 2-oxoglutarate metabolism n/a
127 Q9KMN1_ACO Q9KMN1 Chloramphenicol acetyltransferase (EC n/a
128 Q92993_ACO Q92993 Histone acetyltransferase KAT5 n/a
129 Q59DX8_ACO Q59DX8 N-alpha-acetyltransferase 80 (DmNAA80) n/a
130 Q9BXJ9_ACO Q9BXJ9 N-alpha-acetyltransferase 15, NatA n/a
131 P28790_ACO P28790 3-ketoacyl-CoA thiolase (EC n/a
132 P37613_ACO P37613 PanD regulatory factor n/a
133 O95251_ACO O95251 Histone acetyltransferase KAT7 n/a
134 A0A8M0FGV6_ACO A0A8M0FGV6 N-acetyltransferase n/a
135 Q92L60_ACO Q92L60 Acetyltransferase (EC 2.3.1.-) n/a
136 D2A2Z2_ACO D2A2Z2 Dopamine N-acetyltransferase-like Protein n/a
137 B2RK03_ACO B2RK03 Phosphate acetyltransferase (EC n/a
138 I6XHI4_ACO I6XHI4 Steroid 3-ketoacyl-CoA thiolase n/a
139 P21673_ACO P21673 Diamine acetyltransferase 1 n/a
140 Q9HX72_ACO Q9HX72 Acetyltransferase PA3944 (EC n/a
141 A0A059X981_ACO A0A059X981 Aminoglycoside N(3)-acetyltransferase (EC n/a
142 Q5FWF5_ACO Q5FWF5 N-acetyltransferase ESCO1 (EC n/a
143 O53831_ACO O53831 Mycothiol acetyltransferase (MSH n/a
144 A0A0D6HUM3_ACO A0A0D6HUM3 CopG family transcriptional n/a
145 B1L3C9_ACO B1L3C9 Acyl-CoA synthetase (NDP n/a
146 Q9XB60_ACO Q9XB60 Carboxymethylproline synthase (EC n/a
147 P76539_ACO P76539 Acetyltransferase YpeA (EC n/a
148 Q8TE04_ACO Q8TE04 Pantothenate kinase 1 n/a
149 P0A790_ACO P0A790 Aspartate 1-decarboxylase (EC n/a
150 Q81NK7_ACO Q81NK7 Streptothricin acetyltransferase n/a
151 A0A0A8UKD4_ACO A0A0A8UKD4 N-terminal acetyltransferase, GNAT n/a
152 Q2YRK4_ACO Q2YRK4 GCN5-related N-acetyltransferase (EC n/a
153 Q18A66_ACO Q18A66 Acetyltransferase (EC 2.3.1.-) n/a
154 Q00955_ACO Q00955 Acetyl-CoA carboxylase (ACC) n/a
155 P07097_ACO P07097 Acetyl-CoA acetyltransferase (EC n/a
156 Q8ZPD3_ACO Q8ZPD3 L-methionine sulfoximine/L-methionine sulfone n/a
157 E8XFW6_ACO E8XFW6 Acetyltransferase n/a
158 P16426_ACO P16426 Phosphinothricin N-acetyltransferase (PPT n/a
159 Q09472_ACO Q09472 Histone acetyltransferase p300 n/a
160 P69902_ACO P69902 Formyl-CoA:oxalate CoA-transferase (FCOCT) n/a
161 E9AW84_ACO E9AW84 propanoyl-CoA C-acyltransferase (EC n/a
162 P0ACC7_ACO P0ACC7 Bifunctional protein GlmU n/a
163 Q47764_ACO Q47764 Aac(6')-Ii protein n/a
164 Q08649_ACO Q08649 Histone acetyltransferase ESA1 n/a
165 Q9HVP3_ACO Q9HVP3 N-acetyltransferase domain-containing protein n/a
166 O25094_ACO O25094 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (EC n/a
167 Q6N8A5_ACO Q6N8A5 GCN5-related N-acetyltransferase:Aminotransferase, class-II n/a
168 A0A2A9IR05_ACO A0A2A9IR05 deleted n/a
169 P76077_ACO P76077 1,2-phenylacetyl-CoA epoxidase, subunit n/a
170 Q94521_ACO Q94521 Arylalkylamine N-acetyltransferase 1 n/a
171 P53396_ACO P53396 ATP-citrate synthase (EC n/a
172 Q980R9_ACO Q980R9 N-alpha-acetyltransferase (NAT) (EC n/a
173 Q04KU2_ACO Q04KU2 Bifunctional protein GlmU n/a