Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: ADENINE
PDB ligand accession: ADE
DrugBank: DB00173
PubChem: 190
ChEMBL: CHEMBL226345
InChI Key: GFFGJBXGBJISGV-UHFFFAOYSA-N
SMILES: c1[nH]c2c(n1)c(ncn2)N

ClassyFire chemical classification:

List of proteins that are targets for ADE

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q9UIF8_ADE Q9UIF8 Bromodomain adjacent to n/a
2 A0A0U3AGT1_ADE A0A0U3AGT1 Purine nucleoside phosphorylase n/a
3 Q6P0Y1_ADE Q6P0Y1 non-specific serine/threonine protein n/a
4 A6T4W3_ADE A6T4W3 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH n/a
5 Q27679_ADE Q27679 adenine phosphoribosyltransferase (EC n/a
6 B6THD4_ADE B6THD4 Pyrimidine-specific ribonucleoside hydrolase n/a
7 P24247_ADE P24247 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH n/a
8 Q00955_ADE Q00955 Acetyl-CoA carboxylase (ACC) n/a
9 P24476_ADE P24476 Ribosome-inactivating protein dianthin-30 n/a
10 P22244_ADE P22244 Protein synthesis inhibitor n/a
11 D2QIK7_ADE D2QIK7 Purine nucleoside phosphorylase n/a
12 A0A0E2ZLA9_ADE A0A0E2ZLA9 Adenine phosphoribosyltransferase (APRT) n/a
13 B3EWQ9_ADE B3EWQ9 Lectin alpha chain n/a
14 Q9BMI9_ADE Q9BMI9 Purine nucleoside phosphorylase n/a
15 P07900_ADE P07900 Heat shock protein n/a
16 P10297_ADE P10297 Antiviral protein I n/a
17 P09989_ADE P09989 Ribosome-inactivating protein alpha-trichosanthin n/a
18 Q9Y3B4_ADE Q9Y3B4 Splicing factor 3B n/a
19 P11142_ADE P11142 Heat shock cognate n/a
20 P53396_ADE P53396 ATP-citrate synthase (EC n/a
21 Q47UY5_ADE Q47UY5 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH n/a
22 P83847_ADE P83847 Adenine DNA glycosylase n/a
23 Q57V32_ADE Q57V32 adenine phosphoribosyltransferase (EC n/a
24 P81446_ADE P81446 Beta-galactoside-specific lectin 1 n/a
25 Q6P1N9_ADE Q6P1N9 Deoxyribonuclease TATDN1 (EC n/a
26 Q62074_ADE Q62074 Protein kinase C n/a
27 O24915_ADE O24915 Aminodeoxyfutalosine nucleosidase (AFL n/a
28 P84853_ADE P84853 Ribosome-inactivating protein PD-L1/PD-L2 n/a
29 Q837K0_ADE Q837K0 Deacetylase EF_0837 (EC n/a
30 P69503_ADE P69503 Adenine phosphoribosyltransferase (APRT) n/a
31 A0A197BYF0_ADE A0A197BYF0 deleted n/a
32 Q9YAQ8_ADE Q9YAQ8 S-methyl-5'-thioadenosine phosphorylase (EC n/a
33 P55915_ADE P55915 Concanavalin-Br (Con Br) n/a
34 P25891_ADE P25891 Ribosome-inactivating protein 3 n/a
35 P49435_ADE P49435 Adenine phosphoribosyltransferase 1 n/a
36 Q2YKI6_ADE Q2YKI6 Purine-binding protein BAB2_0673 n/a
37 P09385_ADE P09385 Shiga-like toxin 2 n/a
38 B0B7H9_ADE B0B7H9 deleted n/a
39 P23339_ADE P23339 Antiviral protein S n/a
40 Q8YBL1_ADE Q8YBL1 5'-methylthioadenosine nucleosidase / n/a
41 P16094_ADE P16094 Ribosome-inactivating protein momordin n/a
42 E8NLP5_ADE E8NLP5 deleted n/a
43 P25321_ADE P25321 cAMP-dependent protein kinase n/a
44 Q8RLY5_ADE Q8RLY5 Nucleoside 2-deoxyribosyltransferase (Nucleoside n/a
45 Q97W95_ADE Q97W95 Purine phosphoribosyltransferase (GpT-1) n/a
46 Q9WBP8_ADE Q9WBP8 Capsid protein n/a
47 P0ACP7_ADE P0ACP7 HTH-type transcriptional repressor n/a
48 P0DTD1_ADE P0DTD1 Replicase polyprotein 1ab n/a
49 Q99321_ADE Q99321 Diphosphoinositol polyphosphate phosphohydrolase n/a
50 P11217_ADE P11217 Glycogen phosphorylase, muscle n/a
51 P84854_ADE P84854 Ribosome-inactivating protein PD-L3/PD-L4 n/a
52 Q74ML9_ADE Q74ML9 NEQ131 n/a
53 Q9C9G4_ADE Q9C9G4 Endonuclease 2 (AtENDO2) n/a
54 P33186_ADE P33186 Ribosome-inactivating protein gelonin n/a
55 P02879_ADE P02879 Ricin [Cleaved into: n/a
56 A0KIZ1_ADE A0KIZ1 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH n/a
57 Q5CPH1_ADE Q5CPH1 Adenosylhomocysteinase (EC 3.13.2.1) n/a
58 O50162_ADE O50162 adenosylhomocysteine nucleosidase (EC n/a
59 D5SMY7_ADE D5SMY7 Purine nucleoside phosphorylase n/a
60 Q96EP1_ADE Q96EP1 E3 ubiquitin-protein ligase n/a
61 Q03656_ADE Q03656 Serine/threonine-protein kinase SKY1 n/a
62 A0KGU9_ADE A0KGU9 MTA/SAH nucleosidase (EC n/a
63 Q13126_ADE Q13126 S-methyl-5'-thioadenosine phosphorylase (EC n/a
64 Q8Y5E4_ADE Q8Y5E4 Diadenylate cyclase (DAC) n/a
65 Q81LL4_ADE Q81LL4 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH n/a
66 Q9I6Y4_ADE Q9I6Y4 Adenine deaminase (ADE) n/a
67 B0TZL4_ADE B0TZL4 adenosylhomocysteine nucleosidase (EC n/a
68 A0A087WNH6_ADE A0A087WNH6 Adenosylhomocysteinase (EC 3.13.2.1) n/a
69 Q9I685_ADE Q9I685 Adenosylhomocysteinase (EC 3.13.2.1) n/a
70 P11086_ADE P11086 Phenylethanolamine N-methyltransferase (PNMTase) n/a
71 Q9T0I8_ADE Q9T0I8 5'-methylthioadenosine nucleosidase (MTA n/a
72 P07741_ADE P07741 Adenine phosphoribosyltransferase (APRT) n/a
73 O15530_ADE O15530 3-phosphoinositide-dependent protein kinase n/a
74 B1MMZ4_ADE B1MMZ4 Probable nicotinate-nucleotide adenylyltransferase n/a
75 P24666_ADE P24666 Low molecular weight n/a
76 O14757_ADE O14757 Serine/threonine-protein kinase Chk1 n/a
77 A0A0N0C224_ADE A0A0N0C224 deleted n/a
78 O00763_ADE O00763 Acetyl-CoA carboxylase 2 n/a
79 O34925_ADE O34925 Purine nucleoside phosphorylase n/a
80 A0A133MWI0_ADE A0A133MWI0 Probable nicotinate-nucleotide adenylyltransferase n/a
81 Q13705_ADE Q13705 Activin receptor type-2B n/a
82 D9J2T9_ADE D9J2T9 rRNA N-glycosylase (EC n/a
83 P81460_ADE P81460 Concanavalin-A (Con A) n/a
84 J9VRT5_ADE J9VRT5 Diphosphomevalonate decarboxylase (EC n/a
85 P17802_ADE P17802 Adenine DNA glycosylase n/a
86 Q9V2B6_ADE Q9V2B6 Restriction endonuclease type n/a
87 P78362_ADE P78362 SRSF protein kinase n/a
88 Q05603_ADE Q05603 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (NN:DBI n/a
89 Q9BY49_ADE Q9BY49 Peroxisomal trans-2-enoyl-CoA reductase n/a
90 P23874_ADE P23874 Serine/threonine-protein kinase toxin n/a
91 Q30QR2_ADE Q30QR2 adenosylhomocysteine nucleosidase (EC n/a
92 Q9SP37_ADE Q9SP37 Adenosylhomocysteinase (AdoHcyase) (EC n/a
93 P40347_ADE P40347 Low molecular weight n/a
94 P07949_ADE P07949 Proto-oncogene tyrosine-protein kinase n/a
95 Q9HUM0_ADE Q9HUM0 RNA-binding protein Hfq n/a
96 A1R3U3_ADE A1R3U3 Adenine deaminase (ADE) n/a
97 B2RKN6_ADE B2RKN6 Purine nucleoside phosphorylase n/a
98 Q03629_ADE Q03629 Uncharacterized protein YML079W n/a
99 Q7XA67_ADE Q7XA67 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTA/SAH n/a
100 B9U139_ADE B9U139 Apyrase (EC 3.6.1.5) n/a
101 P66881_ADE P66881 5'/3'-nucleotidase SurE (EC n/a
102 P05045_ADE P05045 Seed lectin subunit n/a
103 Q7DM12_ADE Q7DM12 Abrin A-chain n/a
104 Q3JW91_ADE Q3JW91 Phosphopantetheine adenylyltransferase (EC n/a
105 Q5SL87_ADE Q5SL87 Holliday junction branch n/a
106 I0B503_ADE I0B503 S-methyl-5'-thioadenosine phosphorylase (EC n/a
107 Q66DQ2_ADE Q66DQ2 Adenine phosphoribosyltransferase (APRT) n/a
108 A0A0E1SMD9_ADE A0A0E1SMD9 deleted n/a
109 B1MDI3_ADE B1MDI3 tRNA (guanine-N(1)-)-methyltransferase (EC n/a
110 Q9ZMY2_ADE Q9ZMY2 Aminodeoxyfutalosine nucleosidase (AFL n/a