Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: ALANINE
PDB ligand accession: ALA
DrugBank: DB00160
PubChem: 5950;7311724;
ChEMBL: CHEMBL279597
InChI Key: QNAYBMKLOCPYGJ-REOHCLBHSA-N
SMILES: CC(C(=O)O)N

ClassyFire chemical classification:

List of proteins that are targets for ALA

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q9GK12_ALA Q9GK12 Peptidoglycan recognition protein n/a
2 H1XW48_ALA H1XW48 MutT/NUDIX family protein n/a
3 P04825_ALA P04825 Aminopeptidase N (EC n/a
4 P31153_ALA P31153 S-adenosylmethionine synthase isoform n/a
5 Q97SB9_ALA Q97SB9 deleted n/a
6 P00950_ALA P00950 Phosphoglycerate mutase 1 n/a
7 Q9BRJ2_ALA Q9BRJ2 Large ribosomal subunit n/a
8 Q8NK89_ALA Q8NK89 Alpha-L-arabinofuranosidase B (ABF n/a
9 Q9SX29_ALA Q9SX29 ATP-dependent Clp protease n/a
10 B6YT87_ALA B6YT87 cysteine desulfurase (EC n/a
11 P0AGC3_ALA P0AGC3 Soluble lytic murein n/a
12 Q5SI02_ALA Q5SI02 L-glutamate gamma-semialdehyde dehydrogenase n/a
13 Q9BZJ0_ALA Q9BZJ0 Crooked neck-like protein n/a
14 Q9HTW6_ALA Q9HTW6 Xaa-Pro aminopeptidase (EC n/a
15 P40926_ALA P40926 Malate dehydrogenase, mitochondrial n/a
16 P15145_ALA P15145 Aminopeptidase N (AP-N) n/a
17 Q1JGN6_ALA Q1JGN6 deleted n/a
18 Q9RQJ2_ALA Q9RQJ2 Peptidylarginine deiminase (EC n/a
19 O67323_ALA O67323 Alanine--tRNA ligase (EC n/a
20 P05092_ALA P05092 Peptidyl-prolyl cis-trans isomerase n/a
21 Q9KL26_ALA Q9KL26 Methyl-accepting chemotaxis protein n/a
22 D7DTD6_ALA D7DTD6 Jacalin-type lectin domain-containing n/a
23 Q92552_ALA Q92552 Small ribosomal subunit n/a
24 O13702_ALA O13702 Glycerol dehydrogenase 1 n/a
25 A0A318BC23_ALA A0A318BC23 Aspartate aminotransferase family n/a
26 O32164_ALA O32164 Cysteine desulfurase SufS n/a
27 M4GGR7_ALA M4GGR7 Catalase (EC 1.11.1.6) n/a
28 Q5ZRW2_ALA Q5ZRW2 Inorganic pyrophosphatase (EC n/a
29 A1E280_ALA A1E280 Tryptophan 6-halogenase ThaL n/a
30 O34508_ALA O34508 L-Ala-D/L-Glu epimerase (AE n/a
31 A0A173M0G2_ALA A0A173M0G2 Taste receptor, type n/a
32 A0A3X8N4T9_ALA A0A3X8N4T9 deleted n/a
33 Q5H3Z2_ALA Q5H3Z2 Peptide deformylase (PDF) n/a
34 P20433_ALA P20433 DNA-directed RNA polymerase n/a
35 B0TZW0_ALA B0TZW0 L-amino acid-D/L-Glu epimerase n/a
36 F0QP95_ALA F0QP95 deleted n/a
37 O67077_ALA O67077 ATP-dependent zinc metalloprotease n/a
38 P61589_ALA P61589 Transforming protein RhoA n/a
39 Q08278_ALA Q08278 Mediator of RNA n/a
40 Q5M4H8_ALA Q5M4H8 Di-or tripeptide:H+ symporter n/a
41 P39641_ALA P39641 Alanine--anticapsin ligase (EC n/a
42 Q8EHE6_ALA Q8EHE6 Proton:oligopeptide symporter POT n/a
43 Q9HCS7_ALA Q9HCS7 Pre-mRNA-splicing factor SYF1 n/a
44 Q6LX42_ALA Q6LX42 Sodium/alanine symporter AgcS n/a
45 A0A418LHZ8_ALA A0A418LHZ8 deleted n/a
46 P15057_ALA P15057 Lysozyme (EC 3.2.1.17) n/a
47 Q3LSM4_ALA Q3LSM4 Alanine--glyoxylate aminotransferase (EC n/a
48 O60231_ALA O60231 Pre-mRNA-splicing factor ATP-dependent n/a
49 O75533_ALA O75533 Splicing factor 3B n/a
50 P24627_ALA P24627 Lactotransferrin (Lactoferrin) (EC n/a
51 A7Y7W1_ALA A7Y7W1 Periplasmic dipeptide-binding protein n/a
52 A0A173M094_ALA A0A173M094 Taste receptor type n/a
53 Q96SB4_ALA Q96SB4 SRSF protein kinase n/a
54 A0MK70_ALA A0MK70 Fiber-1 n/a
55 B4RKE7_ALA B4RKE7 Pantothenate synthetase (PS) n/a
56 Q9HVZ7_ALA Q9HVZ7 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (EC n/a
57 P82914_ALA P82914 Small ribosomal subunit n/a
58 A3FQ68_ALA A3FQ68 Peptidyl-prolyl cis-trans isomerase n/a
59 P41896_ALA P41896 Transcription initiation factor n/a
60 B7CIR9_ALA B7CIR9 deleted n/a
61 P38633_ALA P38633 Mediator of RNA n/a
62 C1F2K5_ALA C1F2K5 Beta-glucuronidase C-terminal domain-containing n/a
63 A3RXB7_ALA A3RXB7 N-acetyl-D-hexosamine oxidase (HexNAcO) n/a
64 Q5L1G5_ALA Q5L1G5 Amino acid transporter n/a
65 P04050_ALA P04050 DNA-directed RNA polymerase n/a
66 Q7CX36_ALA Q7CX36 ABC transporter, substrate n/a
67 P9WFY1_ALA P9WFY1 Tryptophan synthase alpha n/a
68 P14618_ALA P14618 Pyruvate kinase PKM n/a
69 Q96GC5_ALA Q96GC5 Large ribosomal subunit n/a
70 O93970_ALA O93970 Peptidyl-prolyl cis-trans isomerase n/a
71 E1QJV5_ALA E1QJV5 Beta-lactamase (EC 3.5.2.6) n/a
72 Q8RAK6_ALA Q8RAK6 Alanine racemase 1 n/a
73 Q8GGP1_ALA Q8GGP1 Conserved hypthetical protein n/a
74 Q15459_ALA Q15459 Splicing factor 3A n/a
75 P08579_ALA P08579 U2 small nuclear n/a
76 A0A069QJX4_ALA A0A069QJX4 Transglycosylase SLT domain-containing n/a
77 P96084_ALA P96084 Proline iminopeptidase (PIP) n/a
78 Q9Z4J8_ALA Q9Z4J8 1,4-beta-N-acetylmuramidase (EC 3.2.1.17, n/a
79 Q9NP92_ALA Q9NP92 Large ribosomal subunit n/a
80 P41052_ALA P41052 Membrane-bound lytic murein n/a
81 P14902_ALA P14902 Indoleamine 2,3-dioxygenase 1 n/a
82 P62166_ALA P62166 Neuronal calcium sensor n/a
83 D3T7F1_ALA D3T7F1 Biotin and thiamin n/a
84 Q02880_ALA Q02880 DNA topoisomerase 2-beta n/a
85 Q8TAD8_ALA Q8TAD8 Smad nuclear-interacting protein n/a
86 P00772_ALA P00772 Chymotrypsin-like elastase family n/a
87 O60306_ALA O60306 RNA helicase aquarius n/a
88 A6YT91_ALA A6YT91 MHC class I n/a
89 P08518_ALA P08518 DNA-directed RNA polymerase n/a
90 Q11T61_ALA Q11T61 D-Ala-D/L-Ala epimerase (EC n/a
91 P11974_ALA P11974 Pyruvate kinase PKM n/a
92 Q736M3_ALA Q736M3 Gamma-D-glutamyl-L-lysine dipeptidyl-peptidase (EC n/a
93 O67854_ALA O67854 Na(+):neurotransmitter symporter (Snf n/a
94 O31562_ALA O31562 Putative metal-dependent hydrolase n/a
95 I6Y4D2_ALA I6Y4D2 N-acetylmuramoyl-L-alanine amidase Rv3717 n/a
96 P38782_ALA P38782 Mediator of RNA n/a
97 Q07955_ALA Q07955 Serine/arginine-rich splicing factor n/a
98 Q9EY50_ALA Q9EY50 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase (EC n/a
99 Q13526_ALA Q13526 Peptidyl-prolyl cis-trans isomerase n/a
100 P00800_ALA P00800 Thermolysin (EC 3.4.24.27) n/a
101 A0A0R1IQH8_ALA A0A0R1IQH8 deleted n/a
102 D9J2T9_ALA D9J2T9 rRNA N-glycosylase (EC n/a
103 Q8A921_ALA Q8A921 Beta-galactosidase n/a
104 B0FZ76_ALA B0FZ76 Alpha-amylase (EC 3.2.1.1) n/a
105 Q15046_ALA Q15046 Lysine--tRNA ligase (EC n/a
106 Q9H2W6_ALA Q9H2W6 Large ribosomal subunit n/a
107 Q6RYW5_ALA Q6RYW5 Outer membrane protein n/a
108 Q9WXM1_ALA Q9WXM1 L-Ala-D/L-Glu epimerase (AE n/a
109 Q6ZXC0_ALA Q6ZXC0 Metallocarboxypeptidase (EC 3.4.17.19) n/a
110 Q15428_ALA Q15428 Splicing factor 3A n/a
111 Q6P2Q9_ALA Q6P2Q9 Pre-mRNA-processing-splicing factor 8 n/a
112 Q8VPD4_ALA Q8VPD4 L-amino acid oxidase n/a
113 O00560_ALA O00560 Syntenin-1 (Melanoma differentiation-associated n/a
114 A0A4Y5PW23_ALA A0A4Y5PW23 Allophycocyanin beta n/a
115 A0A4Y5PW22_ALA A0A4Y5PW22 Allophycocyanin alpha n/a
116 A0A0H6VSA0_ALA A0A0H6VSA0 deleted n/a
117 N0DKS8_ALA N0DKS8 Sodium pumping rhodopsin n/a
118 Q3MFZ5_ALA Q3MFZ5 Amino acid/amide ABC n/a
119 P50440_ALA P50440 Glycine amidinotransferase, mitochondrial n/a
120 P00749_ALA P00749 Urokinase-type plasminogen activator n/a
121 Q8A861_ALA Q8A861 L-Ala-D/L-Glu epimerase (AE n/a
122 E9P5T5_ALA E9P5T5 Glutamate receptor 1 n/a
123 P20436_ALA P20436 DNA-directed RNA polymerases n/a
124 Q3K7T6_ALA Q3K7T6 Putative methyl-accepting chemotaxis n/a
125 A0A0R4I973_ALA A0A0R4I973 ML032222a iGluR n/a
126 A9CIT6_ALA A9CIT6 Dipeptide epimerase (EC n/a
127 Q28943_ALA Q28943 Dihydropyrimidine dehydrogenase [NADP(+)] n/a
128 Q988B8_ALA Q988B8 Pyridoxamine--pyruvate transaminase (EC n/a
129 Q9UNP9_ALA Q9UNP9 Peptidyl-prolyl cis-trans isomerase n/a
130 P52011_ALA P52011 Peptidyl-prolyl cis-trans isomerase n/a
131 Q15393_ALA Q15393 Splicing factor 3B n/a