Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL[HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
PDB ligand accession: AR6
DrugBank: DB02059
PubChem: 447048
ChEMBL: n/a
InChI Key: SRNWOUGRCWSEMX-ZQSHOCFMSA-N
SMILES: c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OCC4C(C(C(O4)O)O)O)O)O)N

ClassyFire chemical classification:

List of proteins that are targets for AR6

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P04977_AR6 P04977 Pertussis toxin subunit n/a
2 Q5ZSK8_AR6 Q5ZSK8 SdeD n/a
3 Q9NXA8_AR6 Q9NXA8 NAD-dependent protein deacylase n/a
4 P54922_AR6 P54922 ADP-ribosylhydrolase ARH1 (EC n/a
5 Q46220_AR6 Q46220 Iota toxin component n/a
6 Q10MW4_AR6 Q10MW4 Basic helix-loop-helix, putative, n/a
7 P14300_AR6 P14300 ADP-ribosyl-[dinitrogen reductase] glycohydrolase n/a
8 P0CG48_AR6 P0CG48 Polyubiquitin-C [Cleaved into: n/a
9 A1Z1Q3_AR6 A1Z1Q3 ADP-ribose glycohydrolase MACROD2 n/a
10 Q5GUA3_AR6 Q5GUA3 Inosine-uridine nucleoside N-ribohydrolase n/a
11 I6L8L7_AR6 I6L8L7 poly(ADP-ribose) glycohydrolase (EC n/a
12 P0DTD1_AR6 P0DTD1 Replicase polyprotein 1ab n/a
13 Q9BQ69_AR6 Q9BQ69 ADP-ribose glycohydrolase MACROD1 n/a
14 P0CH08_AR6 P0CH08 Ubiquitin-ribosomal protein eL40A n/a
15 Q8EP31_AR6 Q8EP31 Hypothetical conserved protein n/a
16 Q28CB4_AR6 Q28CB4 NAD-dependent protein deacylase n/a
17 Q460N5_AR6 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 n/a
18 P13639_AR6 P13639 Elongation factor 2 n/a
19 Q5SKW5_AR6 Q5SKW5 ADP-ribose pyrophosphatase n/a
20 A0A0R4IMY7_AR6 A0A0R4IMY7 Transient receptor potential n/a
21 Q9NTG7_AR6 Q9NTG7 NAD-dependent protein deacetylase n/a
22 D1AC29_AR6 D1AC29 Microbial-type PARG catalytic n/a
23 O88622_AR6 O88622 Poly(ADP-ribose) glycohydrolase (EC n/a
24 Q9NX46_AR6 Q9NX46 ADP-ribosylhydrolase ARH3 (ADP-ribose n/a
25 Q9RZM4_AR6 Q9RZM4 Microbial-type PARG catalytic n/a
26 A0A143SL92_AR6 A0A143SL92 Polyprotein P1234 (Non-structural n/a
27 F5B5W8_AR6 F5B5W8 CdtA n/a
28 C9ZP98_AR6 C9ZP98 Macro domain-containing protein n/a
29 Q8N6T7_AR6 Q8N6T7 NAD-dependent protein deacylase n/a
30 Q86W56_AR6 Q86W56 Poly(ADP-ribose) glycohydrolase (EC n/a
31 H3BCW1_AR6 H3BCW1 ADP-ribosylhydrolase ARH3 (ADP-ribose n/a
32 O28751_AR6 O28751 ADP-ribose glycohydrolase AF_1521 n/a
33 P68135_AR6 P68135 Actin, alpha skeletal n/a
34 Q460N3_AR6 Q460N3 Protein mono-ADP-ribosyltransferase PARP15 n/a
35 Q8IXJ6_AR6 Q8IXJ6 NAD-dependent protein deacetylase n/a
36 P04406_AR6 P04406 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) n/a