Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: ARGININE
PDB ligand accession: ARG
DrugBank: DB00125
PubChem: 1549073;5287702;52941769;59294017;59904234;88031296;
ChEMBL: n/a
InChI Key: ODKSFYDXXFIFQN-BYPYZUCNSA-O
SMILES: C(CC(C(=O)O)N)CNC(=[NH2+])N

ClassyFire chemical classification:

List of proteins that are targets for ARG

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P23793_ARG P23793 Arginine deiminase (ADI) n/a
2 A6YT91_ARG A6YT91 MHC class I n/a
3 Q8DCF5_ARG Q8DCF5 Ornithine carbamoyltransferase (OTCase) n/a
4 Q8RCC3_ARG Q8RCC3 ABC-type amino acid n/a
5 P94632_ARG P94632 Lysine export transcriptional n/a
6 Q05506_ARG Q05506 Arginine--tRNA ligase, cytoplasmic n/a
7 P29474_ARG P29474 Nitric oxide synthase n/a
8 Q113V7_ARG Q113V7 Cyanophycin synthetase (EC n/a
9 P60063_ARG P60063 Arginine/agmatine antiporter n/a
10 D9QA55_ARG D9QA55 Arginine repressor n/a
11 C6XGT2_ARG C6XGT2 Putative amino acid-binding n/a
12 P04825_ARG P04825 Aminopeptidase N (EC n/a
13 Q8YMD9_ARG Q8YMD9 Bifunctional arginine dihydrolase/ornithine n/a
14 A0A0F6UK01_ARG A0A0F6UK01 HAMP domain-containing protein n/a
15 P07824_ARG P07824 Arginase-1 (EC 3.5.3.1) n/a
16 P9WQ01_ARG P9WQ01 Acetylglutamate kinase (EC n/a
17 S3MDF0_ARG S3MDF0 Solute-binding protein family n/a
18 P9WPY7_ARG P9WPY7 Argininosuccinate lyase (ASAL) n/a
19 Q5KZC5_ARG Q5KZC5 Nitric oxide synthase n/a
20 W6JQJ6_ARG W6JQJ6 Tryptophan 2-monooxygenase (EC n/a
21 O81100_ARG O81100 Beta-galactosidase (EC 3.2.1.23) n/a
22 Q6PL18_ARG Q6PL18 ATPase family AAA n/a
23 G9MBV2_ARG G9MBV2 Hydroxylase (EC 1.14.11.41) n/a
24 P00698_ARG P00698 Lysozyme C (EC n/a
25 A8DG50_ARG A8DG50 Genome polyprotein n/a
26 Q07075_ARG Q07075 Glutamyl aminopeptidase (EAP) n/a
27 S4TL40_ARG S4TL40 Non-heme iron hydroxylase n/a
28 O33289_ARG O33289 Amino-acid acetyltransferase (EC n/a
29 O34453_ARG O34453 Nitric oxide synthase n/a
30 A0A173M0G2_ARG A0A173M0G2 Taste receptor, type n/a
31 Q8Y7B7_ARG Q8Y7B7 Lmo1369 protein n/a
32 A0A2X0R690_ARG A0A2X0R690 Glutamine transport system n/a
33 Q08BA4_ARG Q08BA4 Neutral amino acid n/a
34 P74535_ARG P74535 Bifunctional arginine dihydrolase/ornithine n/a
35 O78189_ARG O78189 MHC class I n/a
36 E8XCX6_ARG E8XCX6 Cytoplasmic protein n/a
37 Q0ASS9_ARG Q0ASS9 Acetylglutamate kinase (EC n/a
38 Q8TL28_ARG Q8TL28 Ulilysin (EC 3.4.24.-) n/a
39 Q9X2A4_ARG Q9X2A4 Acetylglutamate kinase (EC n/a
40 Q83E49_ARG Q83E49 Arginine-binding protein n/a
41 P29473_ARG P29473 Nitric oxide synthase n/a
42 A0A1D3F609_ARG A0A1D3F609 deleted n/a
43 C5WBZ6_ARG C5WBZ6 deleted n/a
44 A0A0A7CK57_ARG A0A0A7CK57 arginine kinase (EC n/a
45 A0A0F6B499_ARG A0A0F6B499 Lysine/arginine/ornithine transport protein n/a
46 G7CBN9_ARG G7CBN9 Argininosuccinate synthase (EC n/a
47 Q607C7_ARG Q607C7 L-Lys-D/L-Arg epimerase (EC n/a
48 Q8RCC4_ARG Q8RCC4 ABC-type amino acid n/a
49 Q5L1G5_ARG Q5L1G5 Amino acid transporter n/a
50 Q9Y566_ARG Q9Y566 SH3 and multiple n/a
51 P29476_ARG P29476 Nitric oxide synthase n/a
52 Q9XY07_ARG Q9XY07 Arginine kinase (AK) n/a
53 P53608_ARG P53608 Arginase (EC 3.5.3.1) n/a
54 Q834W6_ARG Q834W6 Hydrophobic dipeptide epimerase n/a
55 Q9SCL7_ARG Q9SCL7 Acetylglutamate kinase, chloroplastic n/a
56 A0A7Y0ZV07_ARG A0A7Y0ZV07 Ornithine cyclodeaminase family n/a
57 Q004B5_ARG Q004B5 Arginine kinase Lit n/a
58 P27348_ARG P27348 14-3-3 protein theta n/a
59 O59188_ARG O59188 HTH-type transcriptional regulator n/a
60 Q9JS59_ARG Q9JS59 Probable ABC transporter n/a
61 Q8WTX7_ARG Q8WTX7 Cytosolic arginine sensor n/a
62 P55892_ARG P55892 Motility protein B n/a
63 F8WQK8_ARG F8WQK8 Asp/Glu-specific dipeptidyl-peptidase (EC n/a
64 Q13501_ARG Q13501 Sequestosome-1 (EBI3-associated protein n/a
65 A0A1J1JHR9_ARG A0A1J1JHR9 Orange carotenoid-binding protein n/a
66 P61964_ARG P61964 WD repeat-containing protein n/a
67 P15145_ARG P15145 Aminopeptidase N (AP-N) n/a
68 P16641_ARG P16641 Taurocyamine kinase (EC n/a
69 Q01217_ARG Q01217 Protein ARG5,6, mitochondrial n/a
70 P0A4Y8_ARG P0A4Y8 Arginine repressor n/a
71 P40969_ARG P40969 Centromere DNA-binding protein n/a
72 P59846_ARG P59846 Argininosuccinate synthase (EC n/a
73 B2CZF9_ARG B2CZF9 Endo-1,4-beta-xylanase (EC 3.2.1.8) n/a
74 Q9RQJ2_ARG Q9RQJ2 Peptidylarginine deiminase (EC n/a
75 P11875_ARG P11875 Arginine--tRNA ligase (EC n/a
76 A0A173M094_ARG A0A173M094 Taste receptor type n/a
77 P35049_ARG P35049 Trypsin (EC 3.4.21.4) n/a
78 P35228_ARG P35228 Nitric oxide synthase, n/a
79 O74101_ARG O74101 DNA/RNA-binding protein Alba n/a
80 Q5SLL0_ARG Q5SLL0 Argininosuccinate lyase (ASAL) n/a
81 O31408_ARG O31408 Arginine repressor n/a
82 Q8ZKA9_ARG Q8ZKA9 Arginine-binding periplasmic protein n/a
83 Q9WZ62_ARG Q9WZ62 Amino acid ABC n/a
84 G9MBV4_ARG G9MBV4 Aminotransferase (Capreomycidine synthase n/a
85 Q04MW8_ARG Q04MW8 deleted n/a
86 P0ABQ5_ARG P0ABQ5 Dihydrofolate reductase (EC n/a
87 P0A6D0_ARG P0A6D0 Arginine repressor n/a
88 A0A2I2ZMM7_ARG A0A2I2ZMM7 CD274 molecule n/a
89 Q8DBF5_ARG Q8DBF5 1-deoxy-D-xylulose 5-phosphate reductoisomerase n/a
90 Q5SHN9_ARG Q5SHN9 Large ribosomal subunit n/a
91 Q8KRB4_ARG Q8KRB4 ABC-type dipeptide transport n/a
92 Q5SE95_ARG Q5SE95 L-ornithine N(5)-monooxygenase (OMO) n/a
93 D9J2T9_ARG D9J2T9 rRNA N-glycosylase (EC n/a
94 Q6WZB0_ARG Q6WZB0 Alpha-ketoglutarate-dependent L-arginine hydroxylase n/a
95 Q8SDC5_ARG Q8SDC5 PHIKZ037 n/a
96 Q72JG5_ARG Q72JG5 Amino acid ABC n/a
97 A6GWM2_ARG A6GWM2 Asp/Glu-specific dipeptidyl-peptidase (EC n/a
98 P40337_ARG P40337 von Hippel-Lindau disease n/a
99 P82251_ARG P82251 b(0,+)-type amino acid n/a
100 A0A0H6Q6V3_ARG A0A0H6Q6V3 deleted n/a
101 P32021_ARG P32021 2-oxoglutarate-dependent ethylene/succinate-forming enzyme n/a
102 P02911_ARG P02911 Lysine/arginine/ornithine-binding periplasmic protein n/a
103 A6YEH4_ARG A6YEH4 CmnC n/a
104 O15992_ARG O15992 Arginine kinase (AK) n/a
105 D6ZRZ2_ARG D6ZRZ2 deleted n/a
106 P29477_ARG P29477 Nitric oxide synthase, n/a
107 A0A085T373_ARG A0A085T373 deleted n/a
108 Q9Z869_ARG Q9Z869 Probable ABC transporter n/a
109 Q9BHM6_ARG Q9BHM6 Octopine dehydrogenase (OcDH) n/a
110 Q5ZY78_ARG Q5ZY78 Argininosuccinate synthase (EC n/a
111 Q9KNT2_ARG Q9KNT2 Serine acetyltransferase (EC n/a
112 Q96IY4_ARG Q96IY4 Carboxypeptidase B2 (EC n/a
113 B5TV91_ARG B5TV91 Proliferating cell nuclear n/a
114 P54136_ARG P54136 Arginine--tRNA ligase, cytoplasmic n/a
115 P52286_ARG P52286 Suppressor of kinetochore n/a
116 D0VWX8_ARG D0VWX8 ArtJ n/a
117 O96935_ARG O96935 Aminopeptidase N (EC n/a
118 P13981_ARG P13981 Arginine deiminase (ADI) n/a
119 A0A1R1S5L5_ARG A0A1R1S5L5 DNA/pantothenate metabolism flavoprotein n/a
120 P61769_ARG P61769 Beta-2-microglobulin [Cleaved into: n/a
121 P08819_ARG P08819 Serine carboxypeptidase 2 n/a
122 A0A286R7K5_ARG A0A286R7K5 Arginine kinase (AK) n/a
123 P51541_ARG P51541 Arginine kinase (AK) n/a
124 P29475_ARG P29475 Nitric oxide synthase n/a
125 B3PEE6_ARG B3PEE6 Oligosaccharide 4-alpha-D-glucosyltransferase (EC n/a
126 P01308_ARG P01308 Insulin [Cleaved into: n/a
127 G0WVH3_ARG G0WVH3 ApnAA1 n/a
128 Q8WSF8_ARG Q8WSF8 Soluble acetylcholine receptor n/a
129 A0A0H6VSA0_ARG A0A0H6VSA0 deleted n/a
130 Q5FAK7_ARG Q5FAK7 Amino-acid acetyltransferase (EC n/a
131 P50440_ARG P50440 Glycine amidinotransferase, mitochondrial n/a
132 Q9RVZ5_ARG Q9RVZ5 Aminopeptidase N (EC n/a
133 Q9R9J1_ARG Q9R9J1 Mycosubtilin synthase subunit n/a
134 P17893_ARG P17893 Arginine repressor (Arginine n/a