Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: ASCORBIC ACID
PDB ligand accession: ASC
DrugBank: DB00126
PubChem: 54670067
ChEMBL: CHEMBL196
InChI Key: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
SMILES: C(C(C1C(=C(C(=O)O1)O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for ASC

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 O00469_ASC O00469 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 cofactor
2 Q02809_ASC Q02809 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 cofactor
3 Q96KS0_ASC Q96KS0 Prolyl hydroxylase EGLN2 cofactor
4 Q652L6_ASC Q652L6 Monodehydroascorbate reductase 3, n/a
5 Q32P28_ASC Q32P28 Prolyl 3-hydroxylase 1 cofactor
6 Q8N543_ASC Q8N543 Prolyl 3-hydroxylase OGFOD1 cofactor
7 P00698_ASC P00698 Lysozyme C (EC n/a
8 Q54873_ASC Q54873 Hyaluronate lyase (EC inhibitor
9 Q43758_ASC Q43758 L-ascorbate peroxidase (EC n/a
10 P09172_ASC P09172 Dopamine beta-hydroxylase (EC cofactor
11 A0A1D7R1K6_ASC A0A1D7R1K6 deleted n/a
12 Q9GZT9_ASC Q9GZT9 Egl nine homolog cofactor
13 O14832_ASC O14832 Phytanoyl-CoA dioxygenase, peroxisomal cofactor
14 P39301_ASC P39301 Ascorbate-specific PTS system n/a
15 Q6NS38_ASC Q6NS38 DNA oxidative demethylase activator
16 P29736_ASC P29736 Myrosinase MA1 (EC n/a
17 P19021_ASC P19021 Peptidyl-glycine alpha-amidating monooxygenase cofactor
18 D9J2T9_ASC D9J2T9 rRNA N-glycosylase (EC n/a
19 P13674_ASC P13674 Prolyl 4-hydroxylase subunit cofactor
20 P02883_ASC P02883 Thaumatin I (Thaumatin-1) n/a
21 Q9BY66_ASC Q9BY66 Lysine-specific demethylase 5D cofactor
22 Q8IVL5_ASC Q8IVL5 Prolyl 3-hydroxylase 2 cofactor
23 Q53TN4_ASC Q53TN4 Plasma membrane ascorbate-dependent n/a
24 Q65XA0_ASC Q65XA0 Probable glutathione S-transferase n/a
25 C5WNL8_ASC C5WNL8 L-ascorbate peroxidase (EC n/a
26 Q8WZK8_ASC Q8WZK8 DyP n/a
27 Q02762_ASC Q02762 Ubiquinol-cytochrome c reductase n/a
28 A0A059ZFC5_ASC A0A059ZFC5 Phosphopantetheine adenylyltransferase (EC n/a
29 P00138_ASC P00138 Cytochrome c' n/a
30 Q9NVH6_ASC Q9NVH6 Trimethyllysine dioxygenase, mitochondrial cofactor
31 P24300_ASC P24300 Xylose isomerase (EC substrate
32 O75936_ASC O75936 Gamma-butyrobetaine dioxygenase (EC cofactor
33 Q9A0M7_ASC Q9A0M7 Hyaluronidase, phage associated n/a
34 Q9NXG6_ASC Q9NXG6 Transmembrane prolyl 4-hydroxylase cofactor
35 Q9H6Z9_ASC Q9H6Z9 Prolyl hydroxylase EGLN3 cofactor
36 Q02761_ASC Q02761 Cytochrome b n/a
37 Q54AI1_ASC Q54AI1 heme oxygenase (biliverdin-producing) n/a
38 Q9Z2J0_ASC Q9Z2J0 Solute carrier family n/a
39 Q6N063_ASC Q6N063 2-oxoglutarate and iron-dependent cofactor
40 P00431_ASC P00431 Cytochrome c peroxidase, n/a
41 Q96Q83_ASC Q96Q83 Alpha-ketoglutarate-dependent dioxygenase alkB activator
42 P0DTD1_ASC P0DTD1 Replicase polyprotein 1ab n/a
43 A7MAQ2_ASC A7MAQ2 Dioscorin dioA3 (EC n/a
44 P80025_ASC P80025 Lactoperoxidase (LPO) (EC n/a
45 Q9SWS1_ASC Q9SWS1 Transmembrane ascorbate ferrireductase n/a
46 P78417_ASC P78417 Glutathione S-transferase omega-1 n/a
47 O60568_ASC O60568 Multifunctional procollagen lysine cofactor
48 A0A8T0NWI5_ASC A0A8T0NWI5 L-ascorbate peroxidase (EC n/a