Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: ASPARTIC ACID
PDB ligand accession: ASP
DrugBank: DB00128
PubChem: 5960;44367445;139060126;
ChEMBL: CHEMBL274323
InChI Key: CKLJMWTZIZZHCS-REOHCLBHSA-N
SMILES: C(C(C(=O)O)N)C(=O)O

ClassyFire chemical classification:

List of proteins that are targets for ASP

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 G8UQY8_ASP G8UQY8 Serpin n/a
2 A0A094VUC2_ASP A0A094VUC2 Aldehyde reductase Ahr n/a
3 G3FFN6_ASP G3FFN6 N6-succino-2-amino-2'-deoxyadenylate synthase (EC n/a
4 Q5ZVE3_ASP Q5ZVE3 Aminopeptidase N (EC n/a
5 Q52428_ASP Q52428 Aspartate--tRNA(Asp) ligase (EC n/a
6 P63244_ASP P63244 Small ribosomal subunit n/a
7 Q07075_ASP Q07075 Glutamyl aminopeptidase (EAP) n/a
8 Q57991_ASP Q57991 Probable aspartokinase (EC n/a
9 P25398_ASP P25398 Small ribosomal subunit n/a
10 O66766_ASP O66766 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit n/a
11 P9WFW3_ASP P9WFW3 Aspartate--tRNA(Asp/Asn) ligase (EC n/a
12 P02941_ASP P02941 Methyl-accepting chemotaxis protein n/a
13 I1SBD9_ASP I1SBD9 L-asparaginase (EC 3.5.1.1) n/a
14 P06608_ASP P06608 L-asparaginase (L-ASNase) (EC n/a
15 P32570_ASP P32570 Mediator of RNA n/a
16 Q9RNB4_ASP Q9RNB4 McyF n/a
17 Q7L266_ASP Q7L266 Isoaspartyl peptidase/L-asparaginase (EC n/a
18 P08243_ASP P08243 Asparagine synthetase [glutamine-hydrolyzing] substrate
19 P03418_ASP P03418 Nucleoprotein (Protein N) n/a
20 H0W0T5_ASP H0W0T5 asparaginase (EC 3.5.1.1) n/a
21 Q9V0T9_ASP Q9V0T9 Glutamyl-tRNA(Gln) amidotransferase subunit n/a
22 Q9X6W1_ASP Q9X6W1 Beta-lactamase (EC 3.5.2.6) n/a
23 P39377_ASP P39377 Isoaspartyl dipeptidase (EC n/a
24 Q5M4H8_ASP Q5M4H8 Di-or tripeptide:H+ symporter n/a
25 Q5JID0_ASP Q5JID0 Proton/glutamate symporter, SDF n/a
26 P00805_ASP P00805 L-asparaginase 2 (EC n/a
27 P62269_ASP P62269 Small ribosomal subunit n/a
28 P24171_ASP P24171 Dipeptidyl carboxypeptidase (EC n/a
29 P27616_ASP P27616 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC n/a
30 Q12797_ASP Q12797 Aspartyl/asparaginyl beta-hydroxylase (EC n/a
31 P20433_ASP P20433 DNA-directed RNA polymerase n/a
32 P60866_ASP P60866 Small ribosomal subunit n/a
33 P46781_ASP P46781 Small ribosomal subunit n/a
34 P0A786_ASP P0A786 Aspartate carbamoyltransferase catalytic n/a
35 A0A1Q8GMZ7_ASP A0A1Q8GMZ7 deleted n/a
36 P0A6E4_ASP P0A6E4 Argininosuccinate synthase (EC n/a
37 E9P5T5_ASP E9P5T5 Glutamate receptor 1 n/a
38 P62273_ASP P62273 Small ribosomal subunit n/a
39 Q01647_ASP Q01647 Phosphoenolpyruvate carboxylase (PEPC) n/a
40 P00966_ASP P00966 Argininosuccinate synthase (EC n/a
41 P08660_ASP P08660 Lysine-sensitive aspartokinase 3 n/a
42 Q4D3W3_ASP Q4D3W3 aspartate carbamoyltransferase (EC n/a
43 A3F718_ASP A3F718 MHC class I n/a
44 O59010_ASP O59010 Glutamate transporter homolog n/a Kd(nM) = 1.0
45 P62841_ASP P62841 Small ribosomal subunit n/a
46 P0A962_ASP P0A962 L-asparaginase 1 (EC n/a
47 P07998_ASP P07998 Ribonuclease pancreatic (EC n/a
48 A0A6A5PRY4_ASP A0A6A5PRY4 deleted n/a
49 A0A6L1BLL7_ASP A0A6L1BLL7 deleted n/a
50 P30520_ASP P30520 Adenylosuccinate synthetase isozyme n/a substrate
51 P61769_ASP P61769 Beta-2-microglobulin [Cleaved into: n/a
52 P08518_ASP P08518 DNA-directed RNA polymerase n/a
53 O15636_ASP O15636 aspartate carbamoyltransferase (EC n/a
54 O30298_ASP O30298 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase (FBPase/IMPase) (EC n/a
55 A0A6A5PWT7_ASP A0A6A5PWT7 deleted n/a
56 P37595_ASP P37595 Isoaspartyl peptidase (EC n/a
57 P22234_ASP P22234 Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole substrate
58 A6GWM2_ASP A6GWM2 Asp/Glu-specific dipeptidyl-peptidase (EC n/a
59 H0VQC8_ASP H0VQC8 deleted n/a
60 P19491_ASP P19491 Glutamate receptor 2 n/a
61 Q04609_ASP Q04609 Glutamate carboxypeptidase 2 n/a
62 Q76KY2_ASP Q76KY2 Non-ribosomal peptide synthetase n/a
63 Q9UJS0_ASP Q9UJS0 Electrogenic aspartate/glutamate antiporter n/a
64 P45381_ASP P45381 Aspartoacylase (EC 3.5.1.15) n/a
65 Q9RQJ2_ASP Q9RQJ2 Peptidylarginine deiminase (EC n/a
66 A0A376KNM9_ASP A0A376KNM9 L-asparaginase 2 (EC n/a
67 V7CU13_ASP V7CU13 Isoaspartyl peptidase/L-asparaginase 2 n/a
68 A0A377K0N3_ASP A0A377K0N3 L-asparaginase 2 (EC n/a
69 Q113V7_ASP Q113V7 Cyanophycin synthetase (EC n/a
70 P61626_ASP P61626 Lysozyme C (EC n/a
71 O57978_ASP O57978 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC n/a
72 P38633_ASP P38633 Mediator of RNA n/a
73 P04825_ASP P04825 Aminopeptidase N (EC n/a
74 P07017_ASP P07017 Methyl-accepting chemotaxis protein n/a
75 P20933_ASP P20933 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.26) n/a Ki(nM) = 600000.0
76 Q6Q4F4_ASP Q6Q4F4 L-asparaginase (EC 3.5.1.1) n/a
77 Q8ZMX9_ASP Q8ZMX9 L-aspartate oxidase (LASPO) n/a
78 A7JW62_ASP A7JW62 deleted n/a
79 A0QWN3_ASP A0QWN3 Aspartate--tRNA(Asp/Asn) ligase (EC n/a
80 Q51422_ASP Q51422 Aspartate--tRNA(Asp/Asn) ligase (EC n/a
81 P12821_ASP P12821 Angiotensin-converting enzyme (ACE) n/a
82 P14868_ASP P14868 Aspartate--tRNA ligase, cytoplasmic n/a
83 Q07296_ASP Q07296 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC n/a
84 P96257_ASP P96257 Probable glutamine-binding lipoprotein n/a
85 A0A6L0ZRP4_ASP A0A6L0ZRP4 deleted n/a
86 Q91642_ASP Q91642 Alpha-aspartyl dipeptidase (EC n/a
87 Q62645_ASP Q62645 Glutamate receptor ionotropic, n/a
88 P14618_ASP P14618 Pyruvate kinase PKM n/a
89 Q9ZLB9_ASP Q9ZLB9 Probable L-asparaginase (L-ASNase) n/a
90 Q6PI48_ASP Q6PI48 Aspartate--tRNA ligase, mitochondrial n/a
91 P43003_ASP P43003 Excitatory amino acid n/a IC50(nM) = 9300.0
92 P30694_ASP P30694 C4 phosphoenolpyruvate carboxylase n/a
93 P00800_ASP P00800 Thermolysin (EC 3.4.24.27) n/a
94 Q56232_ASP Q56232 Aspartate/prephenate aminotransferase (AspAT n/a
95 Q84VW9_ASP Q84VW9 Phosphoenolpyruvate carboxylase 3 n/a
96 Q03154_ASP Q03154 Aminoacylase-1 (ACY-1) (EC n/a
97 Q97MC0_ASP Q97MC0 Aspartokinase (EC 2.7.2.4) n/a
98 P20436_ASP P20436 DNA-directed RNA polymerases n/a
99 P15145_ASP P15145 Aminopeptidase N (AP-N) n/a
100 A0A6A5Q867_ASP A0A6A5Q867 deleted n/a
101 O75746_ASP O75746 Electrogenic aspartate/glutamate antiporter n/a
102 P43005_ASP P43005 Excitatory amino acid n/a IC50(nM) = 19498.0
103 A0A0F6FBL7_ASP A0A0F6FBL7 deleted n/a
104 P00505_ASP P00505 Aspartate aminotransferase, mitochondrial n/a
105 Q8N9N8_ASP Q8N9N8 Probable RNA-binding protein n/a
106 P17174_ASP P17174 Aspartate aminotransferase, cytoplasmic n/a
107 P38782_ASP P38782 Mediator of RNA n/a
108 P38304_ASP P38304 Mediator of RNA n/a
109 Q9V228_ASP Q9V228 AsnS-like asparaginyl-tRNA synthetase n/a
110 P50286_ASP P50286 L-asparaginase (L-ASNase) (EC n/a
111 A4TVL0_ASP A4TVL0 Cereblon isoform 4 n/a
112 Q9LCC6_ASP Q9LCC6 Aspartate ammonia-lyase (Aspartase) n/a
113 P47822_ASP P47822 Mediator of RNA n/a
114 P36936_ASP P36936 Peptidase E (EC n/a
115 Q7VTS1_ASP Q7VTS1 Exported protein n/a
116 Q88K39_ASP Q88K39 Glutaminase-asparaginase (EC 3.5.1.38) n/a
117 Q0P9X8_ASP Q0P9X8 Major cell-binding factor n/a
118 Q8TZE8_ASP Q8TZE8 L-asparaginase (EC 3.5.1.1) n/a
119 F8WQK8_ASP F8WQK8 Asp/Glu-specific dipeptidyl-peptidase (EC n/a
120 P59846_ASP P59846 Argininosuccinate synthase (EC n/a