Ligand name: (1R,5S)-1,2,3,4,5,6-HEXAHYDRO-8H-1,5-METHANOPYRIDO[1,2-A][1,5]DIAZOCIN-8-ONE
PDB ligand accession: C5E
DrugBank: DB09028
PubChem: 10235
ChEMBL: CHEMBL497939
InChI Key: ANJTVLIZGCUXLD-DTWKUNHWSA-N
SMILES: C1C2CNCC1C3=CC=CC(=O)N3C2

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Alkaloids and derivatives
    • Class: Lupin alkaloids
      • Subclass: Cytisine and derivatives

List of proteins that are targets for C5E

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P32297_C5E	P32297	Neuronal acetylcholine receptor	agonist	EC50(nM) = 26000.0
2	Q15825_C5E	Q15825	Neuronal acetylcholine receptor	agonist
3	Q8WSF8_C5E	Q8WSF8	Soluble acetylcholine receptor	n/a
4	P17787_C5E	P17787	Neuronal acetylcholine receptor	partial agonist	EC50(nM) = 67000.0
5	P43681_C5E	P43681	Neuronal acetylcholine receptor	agonist	Ki(nM) = 0.23 EC50(nM) = 0.42
6	P36544_C5E	P36544	Neuronal acetylcholine receptor	agonist	Ki(nM) = 1420.0 EC50(nM) = 71000.0