Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: CYTIDINE-5'-MONOPHOSPHATE
PDB ligand accession: C5P
DrugBank: DB03403
PubChem: 6131
ChEMBL: CHEMBL307679
InChI Key: IERHLVCPSMICTF-XVFCMESISA-N
SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for C5P

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P30085_C5P P30085 UMP-CMP kinase (EC n/a
2 B4EC22_C5P B4EC22 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
3 Q61420_C5P Q61420 CMP-sialic acid transporter n/a
4 O67099_C5P O67099 Thymidylate kinase (EC n/a
5 P57708_C5P P57708 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
6 Q9D020_C5P Q9D020 Cytosolic 5'-nucleotidase 3A n/a
7 Q6SA23_C5P Q6SA23 Nucleocapsid protein n/a
8 P0A6I0_C5P P0A6I0 Cytidylate kinase (CK) n/a
9 B4Y380_C5P B4Y380 CMP 5-hydroxymethylase n/a
10 Q38DE2_C5P Q38DE2 CCHC-type domain-containing protein n/a
11 Q92484_C5P Q92484 Cyclic GMP-AMP phosphodiesterase n/a
12 Q8RQP5_C5P Q8RQP5 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
13 Q9R1E6_C5P Q9R1E6 Autotaxin (EC 3.1.4.39) n/a
14 B4FZ94_C5P B4FZ94 CMP-sialic acid transporter n/a
15 Q63T71_C5P Q63T71 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
16 O43414_C5P O43414 ERI1 exoribonuclease 3 n/a
17 Q9H9S5_C5P Q9H9S5 Ribitol 5-phosphate transferase n/a
18 Q5SL35_C5P Q5SL35 Cytidylate kinase (CK) n/a
19 Q8TZE0_C5P Q8TZE0 Single-stranded-DNA-specific exonuclease RecJ n/a
20 P61823_C5P P61823 Ribonuclease pancreatic (EC n/a
21 Q9UKV8_C5P Q9UKV8 Protein argonaute-2 (Argonaute2) n/a
22 B1MKD5_C5P B1MKD5 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (CMK) n/a
23 Q96LI5_C5P Q96LI5 CCR4-NOT transcription complex n/a
24 Q5L0U0_C5P Q5L0U0 Orotidine 5'-phosphate decarboxylase n/a
25 I7FJF7_C5P I7FJF7 8-oxo-dGTP diphosphatase (EC n/a
26 Q99447_C5P Q99447 Ethanolamine-phosphate cytidylyltransferase (EC n/a
27 O64726_C5P O64726 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, n/a
28 P0C794_C5P P0C794 Matrix protein (gp18) n/a
29 P42216_C5P P42216 3-deoxy-manno-octulosonate cytidylyltransferase (EC n/a
30 A8QYL1_C5P A8QYL1 Beta-galactoside alpha-2,6-sialyltransferase n/a
31 P0ABQ0_C5P P0ABQ0 Coenzyme A biosynthesis n/a
32 A0A179D1D1_C5P A0A179D1D1 Capsular polysaccharide export n/a
33 Q5ZXN6_C5P Q5ZXN6 Phosphocholine transferase AnkX n/a
34 O26232_C5P O26232 Orotidine 5'-phosphate decarboxylase n/a
35 Q91XB0_C5P Q91XB0 Three-prime repair exonuclease n/a
36 Q96662_C5P Q96662 Genome polyprotein [Cleaved n/a
37 P62617_C5P P62617 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
38 O06961_C5P O06961 Propionate kinase (EC n/a
39 P30850_C5P P30850 Exoribonuclease 2 (EC n/a
40 Q9PM68_C5P Q9PM68 Bifunctional enzyme IspD/IspF n/a
41 Q8RQE8_C5P Q8RQE8 DNA-directed RNA polymerase n/a
42 Q06756_C5P Q06756 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
43 A5LHX0_C5P A5LHX0 Alpha-/beta-galactoside alpha-2,3-sialyltransferase n/a
44 Q9HUM0_C5P Q9HUM0 RNA-binding protein Hfq n/a
45 P20425_C5P P20425 UMP-CMP kinase (EC n/a
46 O27985_C5P O27985 CDP-alcohol phosphatidyltransferase AF-2299-like n/a
47 O67082_C5P O67082 Ribonuclease 3 (EC n/a
48 A0A0H2Z2W8_C5P A0A0H2Z2W8 Capsule polysaccharide export n/a
49 O57978_C5P O57978 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC n/a
50 Q9LAK3_C5P Q9LAK3 Alpha-2,3-/2,8-sialyltransferase (Alpha-2,3/8-sialyltransferase) n/a
51 A0R560_C5P A0R560 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase n/a
52 O66663_C5P O66663 3-deoxy-D-manno-octulosonic acid transferase n/a
53 P11954_C5P P11954 L-threonine dehydratase catabolic n/a
54 A0A101DFK9_C5P A0A101DFK9 CDP-alcohol phosphatidyltransferase AF-2299-like n/a
55 B4Y381_C5P B4Y381 CMP/hydroxymethyl CMP hydrolase n/a
56 O04379_C5P O04379 Protein argonaute 1 n/a
57 Q9BZX2_C5P Q9BZX2 Uridine-cytidine kinase 2 n/a
58 Q5SKR5_C5P Q5SKR5 Uridine kinase (EC n/a
59 B1MB31_C5P B1MB31 Cytidylate kinase (CK) n/a
60 Q02745_C5P Q02745 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (Alpha n/a
61 Q8RQE9_C5P Q8RQE9 DNA-directed RNA polymerase n/a
62 Q1YBX2_C5P Q1YBX2 deleted n/a
63 D9J2T9_C5P D9J2T9 rRNA N-glycosylase (EC n/a
64 P15907_C5P P15907 Beta-galactoside alpha-2,6-sialyltransferase 1 n/a
65 P00669_C5P P00669 Seminal ribonuclease (S-RNase) n/a
66 Q6U8B0_C5P Q6U8B0 Putative N-acetyl glucosaminyl n/a
67 Q8IEE9_C5P Q8IEE9 choline-phosphate cytidylyltransferase (EC n/a
68 P49773_C5P P49773 Adenosine 5'-monophosphoramidase HINT1 n/a
69 P24021_C5P P24021 Nuclease S1 (EC n/a
70 Q9UJ37_C5P Q9UJ37 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 n/a
71 Q9CAK8_C5P Q9CAK8 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, n/a
72 P52637_C5P P52637 Matrix protein (gp18) n/a
73 P0A0Z8_C5P P0A0Z8 N-acylneuraminate cytidylyltransferase (EC n/a
74 P36663_C5P P36663 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
75 Q15KI8_C5P Q15KI8 Alpha-2,3/2,6-sialyltransferase/sialidase n/a
76 O86842_C5P O86842 Ribonuclease J (RNase n/a