Ligand name: 4-(dibenzo[1,2-a:2',1'-d][7]annulen-11-ylidene)-1-methyl-piperidine
PDB ligand accession: C7H
DrugBank: DB00434
PubChem: 2913
ChEMBL: CHEMBL516
InChI Key: JJCFRYNCJDLXIK-UHFFFAOYSA-N
SMILES: CN1CCC(=C2c3ccccc3C=Cc4c2cccc4)CC1

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Dibenzocycloheptenes
      • Subclass: None

List of proteins that are targets for C7H

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P25021_C7H	P25021	Histamine H2 receptor	antagonist
2	P28223_C7H	P28223	5-hydroxytryptamine receptor 2A	antagonist	Ki(nM) = 0.46
3	Q8WTS6_C7H	Q8WTS6	Histone-lysine N-methyltransferase SETD7	n/a	Ki(nM) = 15000.0 IC50(nM) = 1000.0
4	P34969_C7H	P34969	5-hydroxytryptamine receptor 7	antagonist	Ki(nM) = 50.0
5	P08172_C7H	P08172	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 7.0
6	P35367_C7H	P35367	Histamine H1 receptor	antagonist	Ki(nM) = 0.06 Kd(nM) = 5400.0
7	P41595_C7H	P41595	5-hydroxytryptamine receptor 2B	antagonist	Ki(nM) = 1.5
8	P28335_C7H	P28335	5-hydroxytryptamine receptor 2C	antagonist	Ki(nM) = 2.23
9	P20309_C7H	P20309	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 12.0
10	P11229_C7H	P11229	Muscarinic acetylcholine receptor	antagonist	Ki(nM) = 12.0