Ligand name: CHOLIC ACID
PDB ligand accession: CHD
DrugBank: DB02659
PubChem: 221493
ChEMBL: CHEMBL205596
InChI Key: BHQCQFFYRZLCQQ-OELDTZBJSA-N
SMILES: CC(CCC(=O)O)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Lipids and lipid-like molecules
    • Class: Steroids and steroid derivatives
      • Subclass: Bile acids, alcohols and derivatives

List of proteins that are targets for CHD

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	Q02221_CHD	Q02221	Cytochrome c oxidase	n/a
2	P03887_CHD	P03887	NADH-ubiquinone oxidoreductase chain	n/a
3	Q7KZA3_CHD	Q7KZA3	Ferrochelatase (EC 4.98.1.1)	n/a
4	Q6IMW5_CHD	Q6IMW5	Gastrotropin	n/a
5	P07470_CHD	P07470	Cytochrome c oxidase	n/a
6	P62509_CHD	P62509	Estrogen-related receptor gamma	n/a
7	P00414_CHD	P00414	Cytochrome c oxidase	n/a
8	P51161_CHD	P51161	Gastrotropin (GT) (Fatty	n/a
9	Q8BGL3_CHD	Q8BGL3	Sulfotransferase 2A8 (SULT2A8)	n/a
10	P00328_CHD	P00328	Alcohol dehydrogenase S	n/a
11	A0A0F6AY66_CHD	A0A0F6AY66	Putative regulatory protein	n/a
12	Q9I8L5_CHD	Q9I8L5	Fatty acid-binding protein	n/a
13	Q7B8P6_CHD	Q7B8P6	CmeR (Transcriptional repressor)	n/a
14	P00592_CHD	P00592	Phospholipase A2, major	n/a
15	P00423_CHD	P00423	Cytochrome c oxidase	n/a
16	P04054_CHD	P04054	Phospholipase A2 (EC	inhibitor	Kd(nM) = 150000.0
17	P20674_CHD	P20674	Cytochrome c oxidase	n/a
18	P51449_CHD	P51449	Nuclear receptor ROR-gamma	n/a
19	P42026_CHD	P42026	NADH dehydrogenase [ubiquinone]	n/a
20	P68530_CHD	P68530	Cytochrome c oxidase	n/a
21	P00395_CHD	P00395	Cytochrome c oxidase	n/a
22	O00255_CHD	O00255	Menin	n/a
23	P03920_CHD	P03920	NADH-ubiquinone oxidoreductase chain	n/a
24	P10606_CHD	P10606	Cytochrome c oxidase	n/a
25	P00428_CHD	P00428	Cytochrome c oxidase	n/a
26	P00430_CHD	P00430	Cytochrome c oxidase	n/a
27	P00403_CHD	P00403	Cytochrome c oxidase	n/a
28	P13073_CHD	P13073	Cytochrome c oxidase	n/a
29	P15538_CHD	P15538	Cytochrome P450 11B1,	n/a
30	P81400_CHD	P81400	Fatty acid-binding protein	n/a
31	P00415_CHD	P00415	Cytochrome c oxidase	n/a
32	P00918_CHD	P00918	Carbonic anhydrase 2	n/a
33	P16622_CHD	P16622	Ferrochelatase, mitochondrial (EC	n/a
34	P22830_CHD	P22830	Ferrochelatase, mitochondrial (EC	inhibitor
35	P13183_CHD	P13183	Cytochrome c oxidase	n/a
36	P80226_CHD	P80226	Fatty acid-binding protein,	n/a
37	P54965_CHD	P54965	Bile salt hydrolase/transferase	n/a
38	P10175_CHD	P10175	Cytochrome c oxidase	n/a
39	J7H3P9_CHD	J7H3P9	choloylglycine hydrolase (EC	n/a
40	Q96RI1_CHD	Q96RI1	Bile acid receptor	n/a	EC50(nM) = 45000.0
41	P62508_CHD	P62508	Estrogen-related receptor gamma	n/a
42	P07471_CHD	P07471	Cytochrome c oxidase	n/a
43	P23141_CHD	P23141	Liver carboxylesterase 1	inhibitor
44	P00396_CHD	P00396	Cytochrome c oxidase	n/a
45	P00326_CHD	P00326	Alcohol dehydrogenase 1C	n/a