Ligand name: COENZYME A
PDB ligand accession: COA
DrugBank: DB01992
PubChem: 87642
ChEMBL: CHEMBL1213327
InChI Key: RGJOEKWQDUBAIZ-IBOSZNHHSA-N
SMILES: CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)n2cnc3c2ncnc3N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCS)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Nucleosides, nucleotides, and analogues
    • Class: Purine nucleotides
      • Subclass: Purine ribonucleotides

List of proteins that are targets for COA

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	Q75VW8_COA	Q75VW8	n/a
2	P50870_COA	P50870	n/a
3	Q08649_COA	Q08649	n/a
4	O64470_COA	O64470	n/a
5	A1B5Y0_COA	A1B5Y0	n/a
6	Q9KLJ3_COA	Q9KLJ3	n/a
7	P0AGE9_COA	P0AGE9	n/a
8	Q9KPB6_COA	Q9KPB6	n/a
9	Q47764_COA	Q47764	n/a
10	P07097_COA	P07097	n/a
11	O58308_COA	O58308	n/a
12	A0A8M0FGV0_COA	A0A8M0FGV0	n/a
13	Q98D42_COA	Q98D42	n/a
14	P11498_COA	P11498	n/a
15	Q980R9_COA	Q980R9	n/a
16	Q2K340_COA	Q2K340	n/a
17	Q9HUS3_COA	Q9HUS3	n/a
18	Q9HV14_COA	Q9HV14	n/a
19	P24752_COA	P24752	n/a
20	P07896_COA	P07896	n/a
21	Q2RMD6_COA	Q2RMD6	n/a
22	Q6SJ71_COA	Q6SJ71	n/a
23	Q09472_COA	Q09472	n/a
24	Q75VX1_COA	Q75VX1	n/a
25	A0A0S4VB05_COA	A0A0S4VB05	n/a
26	A0A0G9FES3_COA	A0A0G9FES3	n/a
27	A0A0B3C4T8_COA	A0A0B3C4T8	n/a
28	P19097_COA	P19097	n/a
29	P0A4W8_COA	P0A4W8	n/a
30	P77399_COA	P77399	n/a
31	O06587_COA	O06587	n/a
32	O34002_COA	O34002	n/a
33	Q9KL03_COA	Q9KL03	n/a
34	A0QUH3_COA	A0QUH3	n/a
35	Q93S40_COA	Q93S40	n/a
36	A0A0C6EV56_COA	A0A0C6EV56	n/a
37	C5AP75_COA	C5AP75	n/a
38	Q9L2C2_COA	Q9L2C2	n/a
39	A0A2X1DZS9_COA	A0A2X1DZS9	n/a
40	Q9P0Q3_COA	Q9P0Q3	n/a
41	Q92830_COA	Q92830	n/a
42	P24224_COA	P24224	n/a
43	Q8GLI5_COA	Q8GLI5	n/a
44	A0A0H3JRH2_COA	A0A0H3JRH2	n/a
45	A0A3A5LTU8_COA	A0A3A5LTU8	n/a
46	P0ABE7_COA	P0ABE7	n/a
47	Q1D5Y4_COA	Q1D5Y4	n/a
48	A0A059X981_COA	A0A059X981	n/a
49	Q1EMV2_COA	Q1EMV2	n/a
50	O31302_COA	O31302	n/a
51	P96202_COA	P96202	n/a
52	P53396_COA	P53396	n/a
53	P11653_COA	P11653	n/a
54	Q9LCX9_COA	Q9LCX9	n/a
55	Q53796_COA	Q53796	n/a
56	P43886_COA	P43886	n/a
57	P07108_COA	P07108	n/a
58	Q8DUV0_COA	Q8DUV0	n/a
59	B1MJN9_COA	B1MJN9	n/a
60	P56220_COA	P56220	n/a
61	E9AW84_COA	E9AW84	n/a
62	Q8AAN6_COA	Q8AAN6	n/a
63	Q97CT7_COA	Q97CT7	n/a
64	P40149_COA	P40149	n/a
65	U3KRF0_COA	U3KRF0	n/a
66	Q51405_COA	Q51405	n/a
67	A0A6A5Q445_COA	A0A6A5Q445	n/a
68	P07107_COA	P07107	n/a
69	Q8NNJ2_COA	Q8NNJ2	n/a
70	Q5HCZ5_COA	Q5HCZ5	n/a
71	O67224_COA	O67224	n/a
72	Q75VW6_COA	Q75VW6	n/a
73	P00889_COA	P00889	n/a
74	P07597_COA	P07597	n/a
75	O28735_COA	O28735	n/a
76	Q8NC06_COA	Q8NC06	n/a
77	P0A5J4_COA	P0A5J4	n/a
78	Q9W469_COA	Q9W469	n/a
79	Q21A54_COA	Q21A54	n/a
80	A0A0T9N0I0_COA	A0A0T9N0I0	n/a
81	K4L7X3_COA	K4L7X3	n/a
82	Q9HX72_COA	Q9HX72	n/a
83	O06581_COA	O06581	n/a
84	A0A2P1BT02_COA	A0A2P1BT02	n/a
85	P02309_COA	P02309	n/a
86	P04035_COA	P04035	inhibitor
87	O86785_COA	O86785	n/a
88	A4YDT1_COA	A4YDT1	n/a
89	Q9NRN7_COA	Q9NRN7	n/a
90	Q81R98_COA	Q81R98	n/a
91	Q53VX2_COA	Q53VX2	n/a
92	Q9HDE2_COA	Q9HDE2	n/a
93	Q53U84_COA	Q53U84	n/a
94	Q9BWD1_COA	Q9BWD1	n/a
95	Q53554_COA	Q53554	n/a
96	P64016_COA	P64016	n/a
97	D7WGJ0_COA	D7WGJ0	n/a
98	O41136_COA	O41136	n/a
99	P19096_COA	P19096	n/a
100	Q8WYK0_COA	Q8WYK0	n/a
101	P96618_COA	P96618	n/a
102	Q6TFC6_COA	Q6TFC6	n/a
103	B1L3C9_COA	B1L3C9	n/a
104	P9WFK6_COA	P9WFK6	n/a
105	A0A0A8UKD4_COA	A0A0A8UKD4	n/a
106	O68216_COA	O68216	n/a
107	A9KN57_COA	A9KN57	n/a
108	Q97WD2_COA	Q97WD2	n/a
109	Q27198_COA	Q27198	n/a
110	A0A0F7DJC6_COA	A0A0F7DJC6	n/a
111	P0A6R0_COA	P0A6R0	n/a
112	Q58VP7_COA	Q58VP7	n/a
113	C5XXB7_COA	C5XXB7	n/a
114	P10245_COA	P10245	n/a
115	M1HE54_COA	M1HE54	n/a
116	Q9I297_COA	Q9I297	n/a
117	P53597_COA	P53597	n/a
118	Q96EK6_COA	Q96EK6	n/a
119	Q8N0X4_COA	Q8N0X4	n/a
120	P0A8Z5_COA	P0A8Z5	n/a
121	Q94521_COA	Q94521	n/a
122	A0A2K1KKM6_COA	A0A2K1KKM6	n/a
123	Q97NZ8_COA	Q97NZ8	n/a
124	P29808_COA	P29808	n/a
125	A0A0H3K033_COA	A0A0H3K033	n/a
126	A0A2I7WB16_COA	A0A2I7WB16	n/a
127	O53872_COA	O53872	n/a
128	O32003_COA	O32003	n/a
129	Q96562_COA	Q96562	n/a
130	Q2FIA5_COA	Q2FIA5	n/a
131	Q4WCL5_COA	Q4WCL5	n/a
132	I6X469_COA	I6X469	n/a
133	O26010_COA	O26010	n/a
134	Q9RM86_COA	Q9RM86	n/a
135	Q00955_COA	Q00955	n/a
136	A3QAV3_COA	A3QAV3	n/a
137	P43155_COA	P43155	inhibitor
138	Q89VT8_COA	Q89VT8	n/a
139	Q9K9P3_COA	Q9K9P3	n/a
140	C5J4P1_COA	C5J4P1	n/a
141	P9WPE1_COA	P9WPE1	n/a
142	P08997_COA	P08997	n/a
143	O06644_COA	O06644	n/a
144	Q81EE4_COA	Q81EE4	n/a
145	P49327_COA	P49327	n/a
146	P30074_COA	P30074	n/a
147	Q86UY6_COA	Q86UY6	n/a
148	Q9AQH6_COA	Q9AQH6	n/a
149	A9WC36_COA	A9WC36	n/a
150	Q9RCZ5_COA	Q9RCZ5	n/a
151	Q8D151_COA	Q8D151	n/a
152	A0A0Y5D4F5_COA	A0A0Y5D4F5	n/a
153	Q9R381_COA	Q9R381	n/a
154	P39058_COA	P39058	n/a
155	I6XHI4_COA	I6XHI4	n/a
156	A0A1V4VDZ9_COA	A0A1V4VDZ9	n/a
157	C4YFL7_COA	C4YFL7	n/a
158	A0A8M0FGV6_COA	A0A8M0FGV6	n/a
159	O70348_COA	O70348	n/a
160	Q8IK57_COA	Q8IK57	n/a
161	P23875_COA	P23875	n/a
162	P96382_COA	P96382	n/a
163	Q9ZC36_COA	Q9ZC36	n/a
164	Q8X5X6_COA	Q8X5X6	n/a
165	A0A059WZ16_COA	A0A059WZ16	n/a
166	Q9HL57_COA	Q9HL57	n/a
167	Q9KQH5_COA	Q9KQH5	n/a
168	P0A6I3_COA	P0A6I3	n/a
169	A0A384E138_COA	A0A384E138	n/a
170	Q50I20_COA	Q50I20	n/a
171	P17622_COA	P17622	n/a
172	A9IH93_COA	A9IH93	n/a
173	Q97V23_COA	Q97V23	n/a
174	Q814S6_COA	Q814S6	n/a
175	Q03503_COA	Q03503	n/a
176	B2HUN5_COA	B2HUN5	n/a
177	P61830_COA	P61830	n/a
178	Q9HLN2_COA	Q9HLN2	n/a
179	P11245_COA	P11245	n/a
180	Q81UT5_COA	Q81UT5	n/a
181	Q5T8D3_COA	Q5T8D3	n/a
182	Q9RTS8_COA	Q9RTS8	n/a
183	Q9NPJ3_COA	Q9NPJ3	n/a
184	A0A384E139_COA	A0A384E139	n/a
185	Q9GZZ1_COA	Q9GZZ1	n/a
186	Q9CAQ2_COA	Q9CAQ2	n/a
187	Q814K4_COA	Q814K4	n/a
188	E1APK1_COA	E1APK1	n/a
189	Q3V1Y3_COA	Q3V1Y3	n/a
190	H0QE96_COA	H0QE96	n/a
191	P38503_COA	P38503	n/a
192	R9RYW2_COA	R9RYW2	n/a
193	A0A7H5N2N8_COA	A0A7H5N2N8	n/a
194	A0A0D6I3Y9_COA	A0A0D6I3Y9	n/a
195	Q8VK10_COA	Q8VK10	n/a
196	A0A0G2RQ73_COA	A0A0G2RQ73	n/a
197	P18886_COA	P18886	n/a
198	P07460_COA	P07460	n/a
199	P15532_COA	P15532	n/a
200	Q47030_COA	Q47030	n/a
201	Q9AJC4_COA	Q9AJC4	n/a
202	Q8ZKF6_COA	Q8ZKF6	n/a
203	A3LHH1_COA	A3LHH1	n/a
204	C4YDZ9_COA	C4YDZ9	n/a
205	A3DJX6_COA	A3DJX6	n/a
206	Q8U2V3_COA	Q8U2V3	n/a
207	P0A574_COA	P0A574	n/a
208	Q81TK8_COA	Q81TK8	n/a
209	P53590_COA	P53590	n/a
210	Q21A49_COA	Q21A49	n/a
211	Q92831_COA	Q92831	n/a
212	Q5ZRL4_COA	Q5ZRL4	n/a
213	O34468_COA	O34468	n/a
214	A0A385EXR5_COA	A0A385EXR5	n/a
215	O52582_COA	O52582	n/a
216	B1Q2B6_COA	B1Q2B6	n/a
217	Q6NCZ6_COA	Q6NCZ6	n/a
218	Q9X024_COA	Q9X024	n/a
219	Q0ASS9_COA	Q0ASS9	n/a
220	A0A1W7GKH6_COA	A0A1W7GKH6	n/a
221	Q8ZJN9_COA	Q8ZJN9	n/a
222	P11181_COA	P11181	n/a
223	O58836_COA	O58836	n/a
224	Q9HW71_COA	Q9HW71	n/a
225	Q0P9D1_COA	Q0P9D1	n/a
226	O33289_COA	O33289	n/a
227	Q9USH6_COA	Q9USH6	n/a
228	P44886_COA	P44886	n/a
229	Q52424_COA	Q52424	n/a
230	A0A059WV44_COA	A0A059WV44	n/a
231	A0A1H5ILA2_COA	A0A1H5ILA2	n/a
232	A0A063X8M7_COA	A0A063X8M7	n/a
233	Q9KEQ1_COA	Q9KEQ1	n/a
234	A0A0G3H170_COA	A0A0G3H170	n/a
235	J9VFT1_COA	J9VFT1	n/a
236	Q3J5L6_COA	Q3J5L6	n/a
237	B1YEL6_COA	B1YEL6	n/a
238	Q1QD33_COA	Q1QD33	n/a
239	P30419_COA	P30419	n/a
240	P39135_COA	P39135	n/a
241	A0A3E2E808_COA	A0A3E2E808	n/a
242	Q5SH84_COA	Q5SH84	n/a
243	Q12KT8_COA	Q12KT8	n/a
244	B2S6A2_COA	B2S6A2	n/a
245	O14965_COA	O14965	n/a
246	D3EKC1_COA	D3EKC1	n/a
247	Q08AH3_COA	Q08AH3	n/a
248	P14611_COA	P14611	n/a
249	Q92993_COA	Q92993	n/a
250	P0A530_COA	P0A530	n/a
251	P94968_COA	P94968	n/a
252	Q8Y7B7_COA	Q8Y7B7	n/a
253	Q29551_COA	Q29551	n/a
254	P21340_COA	P21340	n/a
255	O32248_COA	O32248	n/a
256	Q9I0Q8_COA	Q9I0Q8	n/a
257	B0B9A0_COA	B0B9A0	n/a
258	P9WFK7_COA	P9WFK7	n/a
259	Q5SIE3_COA	Q5SIE3	n/a
260	A0L8G4_COA	A0L8G4	n/a
261	Q4WCU5_COA	Q4WCU5	n/a
262	P0A5N0_COA	P0A5N0	n/a
263	A0A071KS24_COA	A0A071KS24	n/a
264	P63810_COA	P63810	n/a
265	Q91V12_COA	Q91V12	n/a
266	P31572_COA	P31572	n/a
267	Q5SQI0_COA	Q5SQI0	n/a
268	Q3M362_COA	Q3M362	n/a
269	Q12341_COA	Q12341	n/a
270	P11652_COA	P11652	n/a
271	P0A836_COA	P0A836	n/a
272	P94368_COA	P94368	n/a
273	P13702_COA	P13702	n/a
274	A0A454XSD0_COA	A0A454XSD0	n/a
275	A9X6P7_COA	A9X6P7	n/a
276	Q8GGP1_COA	Q8GGP1	n/a
277	B0YD89_COA	B0YD89	n/a
278	Q88N39_COA	Q88N39	n/a
279	B1MD73_COA	B1MD73	n/a
280	G9MBU1_COA	G9MBU1	n/a
281	P37613_COA	P37613	n/a
282	I1KHY6_COA	I1KHY6	n/a
283	B0XMC1_COA	B0XMC1	n/a
284	Q9Z9H2_COA	Q9Z9H2	n/a
285	O57768_COA	O57768	n/a
286	Q8A1H2_COA	Q8A1H2	n/a
287	P09373_COA	P09373	n/a
288	A0A2S1PH20_COA	A0A2S1PH20	n/a
289	A0A6N0ZM94_COA	A0A6N0ZM94	n/a
290	A0A1X8XLG2_COA	A0A1X8XLG2	n/a
291	A0A0D6G5A8_COA	A0A0D6G5A8	n/a
292	Q9F6D4_COA	Q9F6D4	n/a
293	A3E7Z7_COA	A3E7Z7	n/a
294	P53559_COA	P53559	n/a
295	O67575_COA	O67575	n/a
296	P07464_COA	P07464	n/a
297	Q5HH30_COA	Q5HH30	n/a
298	Q6VE93_COA	Q6VE93	n/a
299	Q5FAK7_COA	Q5FAK7	n/a
300	A0A0D6HE46_COA	A0A0D6HE46	n/a
301	O24146_COA	O24146	n/a
302	A1KUS8_COA	A1KUS8	n/a
303	O53871_COA	O53871	n/a
304	Q99UY8_COA	Q99UY8	n/a
305	A8QZK6_COA	A8QZK6	n/a
306	P28329_COA	P28329	n/a
307	A0A1X8XLG1_COA	A0A1X8XLG1	n/a
308	A0A384E143_COA	A0A384E143	n/a
309	P21673_COA	P21673	n/a
310	A0A1H0A919_COA	A0A1H0A919	n/a
311	Q70AY4_COA	Q70AY4	n/a
312	Q4WUS9_COA	Q4WUS9	n/a
313	Q9H7Z6_COA	Q9H7Z6	n/a
314	A0L8G5_COA	A0L8G5	n/a
315	Q72HK3_COA	Q72HK3	n/a
316	O19069_COA	O19069	n/a
317	P07459_COA	P07459	n/a
318	O06414_COA	O06414	n/a
319	Q9HYX1_COA	Q9HYX1	n/a
320	Q63R74_COA	Q63R74	n/a
321	P68135_COA	P68135	n/a
322	A0A0W8FB26_COA	A0A0W8FB26	n/a
323	A0A8T9DN77_COA	A0A8T9DN77	n/a
324	Q8RR28_COA	Q8RR28	n/a
325	D1A3K7_COA	D1A3K7	n/a
326	F0K5D8_COA	F0K5D8	n/a
327	V5RDR9_COA	V5RDR9	n/a
328	O30409_COA	O30409	n/a
329	P0ACC7_COA	P0ACC7	n/a
330	Q8NRC3_COA	Q8NRC3	n/a
331	A8LRC0_COA	A8LRC0	n/a
332	T2FY33_COA	T2FY33	n/a
333	Q8DUI5_COA	Q8DUI5	n/a
334	Q8N6N7_COA	Q8N6N7	n/a
335	Q1QD55_COA	Q1QD55	n/a
336	Q1D4I1_COA	Q1D4I1	n/a
337	O33336_COA	O33336	n/a
338	A0A059ZFC5_COA	A0A059ZFC5	n/a
339	Q01581_COA	Q01581	n/a
340	Q99VD7_COA	Q99VD7	n/a
341	H2L2M1_COA	H2L2M1	n/a
342	O53831_COA	O53831	n/a
343	Q4QED0_COA	Q4QED0	n/a
344	B2HIZ6_COA	B2HIZ6	n/a
345	E8XKZ3_COA	E8XKZ3	n/a
346	P16426_COA	P16426	n/a
347	Q39VG2_COA	Q39VG2	n/a
348	Q04416_COA	Q04416	n/a
349	P0AEX9_COA	P0AEX9	n/a
350	Q9NUI1_COA	Q9NUI1	n/a
351	Q97ML2_COA	Q97ML2	n/a
352	P09371_COA	P09371	n/a
353	Q5C8M4_COA	Q5C8M4	n/a
354	P9WJY9_COA	P9WJY9	n/a
355	Q88HJ8_COA	Q88HJ8	n/a
356	F1L3N8_COA	F1L3N8	n/a
357	P76077_COA	P76077	n/a
358	Q9H7X0_COA	Q9H7X0	n/a
359	I3VE75_COA	I3VE75	n/a
360	P23141_COA	P23141	n/a
361	Q81Q99_COA	Q81Q99	n/a
362	A0A0D5YK08_COA	A0A0D5YK08	n/a
363	Q8EG98_COA	Q8EG98	n/a
364	Q96I99_COA	Q96I99	n/a
365	A0PQD8_COA	A0PQD8	n/a
366	Q4Q5S8_COA	Q4Q5S8	n/a
367	O29847_COA	O29847	n/a
368	P43577_COA	P43577	n/a
369	A4YI89_COA	A4YI89	n/a
370	O75390_COA	O75390	n/a
371	O25488_COA	O25488	n/a
372	P13249_COA	P13249	n/a
373	O94197_COA	O94197	n/a
374	Q8DRZ8_COA	Q8DRZ8	n/a
375	V5VBK4_COA	V5VBK4	n/a
376	A1KVH5_COA	A1KVH5	n/a
377	P61599_COA	P61599	n/a
378	B1MDL6_COA	B1MDL6	n/a
379	Q47510_COA	Q47510	n/a
380	V5VGF8_COA	V5VGF8	n/a
381	A0AAI9EXQ5_COA	A0AAI9EXQ5	n/a
382	Q96YK1_COA	Q96YK1	n/a
383	Q8ZPC0_COA	Q8ZPC0	n/a
384	B3EY95_COA	B3EY95	n/a
385	P07149_COA	P07149	n/a
386	P69902_COA	P69902	n/a
387	Q4J989_COA	Q4J989	n/a
388	Q8CIB9_COA	Q8CIB9	n/a
389	Q8ZJW4_COA	Q8ZJW4	n/a
390	P42765_COA	P42765	n/a
391	Q39VG1_COA	Q39VG1	n/a
392	Q53396_COA	Q53396	n/a
393	Q5SJP3_COA	Q5SJP3	n/a
394	P48026_COA	P48026	n/a
395	A0QY29_COA	A0QY29	n/a
396	Q5NHF3_COA	Q5NHF3	n/a
397	O85353_COA	O85353	n/a
398	P71727_COA	P71727	n/a
399	Q17427_COA	Q17427	n/a
400	Q6P4V5_COA	Q6P4V5	n/a
401	P47934_COA	P47934	n/a
402	Q5JGC2_COA	Q5JGC2	n/a
403	Q9FD71_COA	Q9FD71	n/a