Ligand name: CO-METHYLCOBALAMIN
PDB ligand accession: COB
DrugBank: DB03614
PubChem: n/a
ChEMBL: n/a
InChI Key: BMOGZGJBQIUQJG-BYLSPCLQSA-N
SMILES: Cc1cc2c(cc1C)n(cn2)C3C(C(C(O3)CO)OP(=O)(O)OC(C)CNC(=O)CCC4(C(C5=[N-]6C4=C(C7=[N]8[Co+2]69([N]1=C(C=C8C(C7CCC(=O)N)(C)C)C(C(C1=C(C1=[N]9C5(C(C1CCC(=O)N)(C)CC(=O)N)C)C)(C)CC(=O)N)CCC(=O)N)C)C)CC(=O)N)C)O

List of proteins that are targets for COB

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q07341_COB Q07341 Corrinoid/iron-sulfur protein small n/a
2 Q9Y4U1_COB Q9Y4U1 Cyanocobalamin reductase / n/a
3 Q07340_COB Q07340 Corrinoid/iron-sulfur protein large n/a
4 Q8GJ31_COB Q8GJ31 Tetrachloroethene reductive dehalogenase n/a
5 Q7Z144_COB Q7Z144 MMACHC-like protein (EC n/a
6 P13009_COB P13009 Methionine synthase (EC n/a
7 Q8RPG0_COB Q8RPG0 Cobalamin-binding protein n/a
8 P80077_COB P80077 Glutamate mutase epsilon n/a
9 Q46389_COB Q46389 5-methyltetrahydrofolate:corrinoid/iron-sulfur protein co-methyltransferase n/a
10 P80078_COB P80078 Glutamate mutase sigma n/a