Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: CYSTEINE
PDB ligand accession: CYS
DrugBank: DB00151
PubChem: 5862;6419722;
ChEMBL: CHEMBL863
InChI Key: XUJNEKJLAYXESH-REOHCLBHSA-N
SMILES: C(C(C(=O)O)N)S

ClassyFire chemical classification:

List of proteins that are targets for CYS

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P07013_CYS P07013 Primosome protein PriB n/a
2 Q16878_CYS Q16878 Cysteine dioxygenase type n/a
3 P40702_CYS P40702 Surface presentation of n/a
4 P08887_CYS P08887 Interleukin-6 receptor subunit n/a
5 P44801_CYS P44801 Aspartate-semialdehyde dehydrogenase (ASA n/a
6 Q6XJV4_CYS Q6XJV4 Cell surface glycoprotein n/a
7 O30347_CYS O30347 Glutathione S-transferase n/a
8 P77444_CYS P77444 Cysteine desulfurase (EC n/a
9 P01887_CYS P01887 Beta-2-microglobulin n/a
10 P08185_CYS P08185 Corticosteroid-binding globulin (CBG) n/a
11 P01901_CYS P01901 H-2 class I n/a
12 Q94734_CYS Q94734 Nitrophorin-4 (NP4) (EC n/a
13 Q9UNN8_CYS Q9UNN8 Endothelial protein C n/a
14 P21888_CYS P21888 Cysteine--tRNA ligase (EC n/a
15 O15570_CYS O15570 Cysteine synthase n/a
16 P60864_CYS P60864 Metallothiol transferase FosB n/a
17 P43616_CYS P43616 Cys-Gly metallodipeptidase DUG1 n/a
18 Q6MZV7_CYS Q6MZV7 Uncharacterized protein DKFZp686C11235 n/a
19 P02768_CYS P02768 Albumin n/a
20 Q9RQJ2_CYS Q9RQJ2 Peptidylarginine deiminase (EC n/a
21 Q0ZB96_CYS Q0ZB96 Serine acetyltransferase (EC n/a
22 P01009_CYS P01009 Alpha-1-antitrypsin (Alpha-1 protease n/a
23 P05326_CYS P05326 Isopenicillin N synthase n/a
24 P38484_CYS P38484 Interferon gamma receptor n/a
25 P80025_CYS P80025 Lactoperoxidase (LPO) (EC n/a
26 P43886_CYS P43886 Serine acetyltransferase (SAT) n/a
27 P00889_CYS P00889 Citrate synthase, mitochondrial n/a
28 P07598_CYS P07598 Periplasmic [Fe] hydrogenase n/a
29 A8YBP8_CYS A8YBP8 Cysteine synthase (EC n/a
30 Q2LKZ0_CYS Q2LKZ0 Genome polyprotein [Cleaved n/a
31 P21816_CYS P21816 Cysteine dioxygenase type n/a
32 P0A542_CYS P0A542 Aspartate-semialdehyde dehydrogenase (ASA n/a
33 Q9KQG2_CYS Q9KQG2 Aspartate-semialdehyde dehydrogenase 1 n/a
34 Q9Y286_CYS Q9Y286 Sialic acid-binding Ig-like n/a
35 P0AES0_CYS P0AES0 Bifunctional glutathionylspermidine synthetase/amidase n/a
36 Q9ES57_CYS Q9ES57 Cell surface glycoprotein n/a
37 P0A9D4_CYS P0A9D4 Serine acetyltransferase (SAT) n/a
38 Q9UGB7_CYS Q9UGB7 Inositol oxygenase (EC n/a
39 P03372_CYS P03372 Estrogen receptor (ER) n/a
40 P61769_CYS P61769 Beta-2-microglobulin [Cleaved into: n/a
41 M7WGH7_CYS M7WGH7 serine O-acetyltransferase (EC n/a
42 Q68FT9_CYS Q68FT9 Selenocysteine lyase (EC n/a
43 A0A0D6I3Y9_CYS A0A0D6I3Y9 Serine acetyltransferase (EC n/a
44 Q9HXN1_CYS Q9HXN1 Membrane-bound lytic murein n/a
45 Q739M9_CYS Q739M9 Metallothiol transferase FosB n/a
46 P0A6W9_CYS P0A6W9 Glutamate--cysteine ligase (EC n/a
47 B6YT87_CYS B6YT87 cysteine desulfurase (EC n/a
48 P00353_CYS P00353 Aspartate-semialdehyde dehydrogenase (ASA n/a
49 P07603_CYS P07603 Periplasmic [Fe] hydrogenase n/a
50 Q9U8X2_CYS Q9U8X2 serine O-acetyltransferase (EC n/a
51 P13599_CYS P13599 IgG receptor FcRn n/a
52 Q9KNT2_CYS Q9KNT2 Serine acetyltransferase (EC n/a
53 Q9X0Z6_CYS Q9X0Z6 [FeFe] hydrogenase maturase n/a
54 P01031_CYS P01031 Complement C5 (C3 n/a
55 P32929_CYS P32929 Cystathionine gamma-lyase (CGL) n/a
56 Q15063_CYS Q15063 Periostin (PN) (Osteoblast-specific n/a
57 P62204_CYS P62204 Calmodulin-2 n/a
58 P00441_CYS P00441 Superoxide dismutase [Cu-Zn] n/a
59 Q9C8E7_CYS Q9C8E7 Glutamate receptor 3.3 n/a
60 P00695_CYS P00695 Lysozyme C (EC n/a
61 Q9X218_CYS Q9X218 Aminotransferase, class V n/a
62 Q5H1U9_CYS Q5H1U9 Cystathionine gamma-synthase n/a
63 Q5F5B5_CYS Q5F5B5 ABC transporter substrate-binding n/a
64 O59010_CYS O59010 Glutamate transporter homolog n/a
65 P00749_CYS P00749 Urokinase-type plasminogen activator n/a
66 P55899_CYS P55899 IgG receptor FcRn n/a
67 Q06A71_CYS Q06A71 glutathione transferase (EC n/a
68 C6XGT2_CYS C6XGT2 Putative amino acid-binding n/a
69 Q0P9S0_CYS Q0P9S0 Amino-acid transporter periplasmic n/a
70 Q5F9M1_CYS Q5F9M1 Amino acid ABC n/a
71 Q00511_CYS Q00511 Uricase (EC 1.7.3.3) n/a
72 Q9ZHG9_CYS Q9ZHG9 L-cysteine/cystine lyase C-DES n/a
73 P14618_CYS P14618 Pyruvate kinase PKM n/a
74 P48357_CYS P48357 Leptin receptor (LEP-R) n/a
75 Q3MFZ5_CYS Q3MFZ5 Amino acid/amide ABC n/a
76 A0A6P3CW71_CYS A0A6P3CW71 cysteine desulfurase (EC n/a
77 Q9YBL2_CYS Q9YBL2 Protein CysO (Cystathionine n/a
78 Q0WKM4_CYS Q0WKM4 Serine acetyltransferase (EC n/a
79 P15260_CYS P15260 Interferon gamma receptor n/a
80 O67141_CYS O67141 Selenocysteine-specific elongation factor n/a
81 P0AFX9_CYS P0AFX9 Sigma-E factor regulatory n/a
82 P00748_CYS P00748 Coagulation factor XII n/a
83 P14784_CYS P14784 Interleukin-2 receptor subunit n/a
84 B6K8Y1_CYS B6K8Y1 Cystathionine beta-lyase, putative n/a
85 O32085_CYS O32085 Cysteine dioxygenase (CDO) n/a