Ligand name: 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE
PDB ligand accession: DZP
DrugBank: DB00829
PubChem: 3016
ChEMBL: CHEMBL12
InChI Key: AAOVKJBEBIDNHE-UHFFFAOYSA-N
SMILES: CN1c2ccc(cc2C(=NCC1=O)c3ccccc3)Cl

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Benzodiazepines
      • Subclass: 1,4-benzodiazepines

List of proteins that are targets for DZP

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	P47870_DZP	P47870	positive allosteric modulator
2	P14867_DZP	P14867	ligand	positive allosteric modulator	Ki(nM) = 12.0 Kd(nM) = 36.0 EC50(nM) = 85.0
3	P02768_DZP	P02768	n/a	Kd(nM) = 24547.0
4	P28472_DZP	P28472	positive allosteric modulator
5	P31644_DZP	P31644	ligand	positive allosteric modulator	Ki(nM) = 11.0 IC50(nM) = 17.0 Kd(nM) = 23.0 EC50(nM) = 45.0
6	P08219_DZP	P08219	n/a
7	P18507_DZP	P18507	ligand	positive allosteric modulator