Ligand name: 5,8,11,14,17-EICOSAPENTAENOIC ACID
PDB ligand accession: EPA
DrugBank: DB00159
PubChem: 446284
ChEMBL: CHEMBL460026
InChI Key: JAZBEHYOTPTENJ-JLNKQSITSA-N
SMILES: CCC=CCC=CCC=CCC=CCC=CCCCC(=O)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Lipids and lipid-like molecules
    • Class: Fatty Acyls
      • Subclass: Fatty acids and conjugates

List of proteins that are targets for EPA

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P05979_EPA	P05979	Prostaglandin G/H synthase	n/a
2	E9NSU2_EPA	E9NSU2	Cytochrome P450 (Terminal	n/a
3	Q8NER1_EPA	Q8NER1	Transient receptor potential	inducer
4	P23219_EPA	P23219	Prostaglandin G/H synthase	inhibitor
5	O60427_EPA	O60427	Acyl-CoA (8-3)-desaturase (EC	agonist
6	P09917_EPA	P09917	Polyunsaturated fatty acid	substrate
7	P37231_EPA	P37231	Peroxisome proliferator-activated receptor	agonist	IC50(nM) = 1600.0 Kd(nM) = 2000.0
8	Q5NUL3_EPA	Q5NUL3	Free fatty acid	n/a
9	O15540_EPA	O15540	Fatty acid-binding protein,	agonist
10	Q05769_EPA	Q05769	Prostaglandin G/H synthase	n/a
11	P35354_EPA	P35354	Prostaglandin G/H synthase	inhibitor
12	Q07869_EPA	Q07869	Peroxisome proliferator-activated receptor	n/a	IC50(nM) = 1100.0
13	Q03181_EPA	Q03181	Peroxisome proliferator-activated receptor	agonist	IC50(nM) = 4000.0
14	O60488_EPA	O60488	Long-chain-fatty-acid--CoA ligase 4	inducer
15	P05413_EPA	P05413	Fatty acid-binding protein,	n/a
16	O14842_EPA	O14842	Free fatty acid	agonist
17	P32418_EPA	P32418	Sodium/calcium exchanger 1	inhibitor