Ligand name: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
PDB ligand accession: EVP
DrugBank: DB00773
PubChem: 36462
ChEMBL: CHEMBL44657
InChI Key: VJJPUSNTGOMMGY-MRVIYFEKSA-N
SMILES: CC1OCC2C(O1)C(C(C(O2)OC3c4cc5c(cc4C(C6C3COC6=O)c7cc(c(c(c7)OC)O)OC)OCO5)O)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Lignans, neolignans and related compounds
    • Class: Lignan lactones
      • Subclass: Podophyllotoxins

List of proteins that are targets for EVP

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	Q99XG5_EVP	Q99XG5	n/a
2	P02768_EVP	P02768	n/a
3	P66937_EVP	P66937	n/a
4	Q02880_EVP	Q02880	inhibitor	IC50(nM) = 70.0 EC50(nM) = 70000.0
5	P11388_EVP	P11388	inhibitor	IC50(nM) = 4700.0 EC50(nM) = 810.0