PDB ligand accession: EZL
DrugBank: DB00311
PubChem:
ChEMBL:
InChI Key: OUZWUKMCLIBBOG-UHFFFAOYSA-N
SMILES: CCOc1ccc2c(c1)sc(n2)S(=O)(=O)N
ClassyFire chemical classification:
- Kingdom: Organic compounds
- Superclass: Organoheterocyclic compounds
- Class: Benzothiazoles
- Subclass: None
- Class: Benzothiazoles
- Superclass: Organoheterocyclic compounds
# | DrugDomain Data | UniProt Accession | Protein name | Drug Action | Affinity data |
---|---|---|---|---|---|
1 | A0A0M3KL20_EZL | A0A0M3KL20 | carbonic anhydrase (EC | n/a | |
2 | Q3JRA0_EZL | Q3JRA0 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | n/a | |
3 | P43166_EZL | P43166 | Carbonic anhydrase 7 | inhibitor | Ki(nM) = 0.78 Kd(nM) = 0.71 |
4 | P22748_EZL | P22748 | Carbonic anhydrase 4 | inhibitor | Ki(nM) = 93.0 |
5 | P00915_EZL | P00915 | Carbonic anhydrase 1 | inhibitor | Ki(nM) = 25.0 IC50(nM) = 8.0 Kd(nM) = 14.0 |
6 | P07451_EZL | P07451 | Carbonic anhydrase 3 | inhibitor | Ki(nM) = 5000.0 |
7 | P00918_EZL | P00918 | Carbonic anhydrase 2 | inhibitor | Ki(nM) = 0.49 IC50(nM) = 0.3 Kd(nM) = 0.71 |