Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: FE3-S4 CLUSTER
PDB ligand accession: F3S
DrugBank: n/a
PubChem: n/a
ChEMBL: n/a
InChI Key: FCXHZBQOKRZXKS-UHFFFAOYSA-N
SMILES: S1[Fe]2S[Fe]3[S]2[Fe]1S3

ClassyFire chemical classification:

List of proteins that are targets for F3S

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P10245_F3S P10245 Ferredoxin n/a
2 P21852_F3S P21852 Periplasmic [NiFe] hydrogenase n/a
3 Q7SIF4_F3S Q7SIF4 Arsenite oxidase subunit n/a
4 P03942_F3S P03942 Ferredoxin n/a
5 A0A164XVV7_F3S A0A164XVV7 deleted n/a
6 P07014_F3S P07014 Succinate dehydrogenase iron-sulfur n/a
7 P0ACD8_F3S P0ACD8 Hydrogenase-1 large chain n/a
8 F2Z6J5_F3S F2Z6J5 hydrogenase (acceptor) (EC n/a
9 P0AC49_F3S P0AC49 Fumarate reductase iron-sulfur n/a
10 P12943_F3S P12943 Periplasmic [NiFe] hydrogenase n/a
11 E1K248_F3S E1K248 cytochrome-c3 hydrogenase (EC n/a
12 D3RV29_F3S D3RV29 hydrogenase (acceptor) (EC n/a
13 P29603_F3S P29603 Ferredoxin n/a
14 P31892_F3S P31892 Uptake hydrogenase small n/a
15 Q1PZD5_F3S Q1PZD5 Nitrite oxidoreductase subunit n/a
16 A0A037Y3E8_F3S A0A037Y3E8 Succinate dehydrogenase iron-sulfur n/a
17 I7M403_F3S I7M403 succinate dehydrogenase (EC n/a
18 G8QM54_F3S G8QM54 DMSO reductase family n/a
19 P39471_F3S P39471 DNA-directed RNA polymerase n/a
20 Q5P5I1_F3S Q5P5I1 Beta-subunit of ethylbenzene n/a
21 V0V766_F3S V0V766 deleted n/a
22 P00214_F3S P00214 Ferredoxin-1 (Ferredoxin I) n/a
23 P69741_F3S P69741 Hydrogenase-2 small chain n/a
24 C9QSC3_F3S C9QSC3 deleted n/a
25 Q6VAL8_F3S Q6VAL8 AroA (Arsenite oxidase n/a
26 P69740_F3S P69740 Hydrogenase-1 small chain n/a
27 Q007T0_F3S Q007T0 Succinate dehydrogenase [ubiquinone] n/a
28 P18188_F3S P18188 Periplasmic [NiFe] hydrogenase n/a
29 P16276_F3S P16276 Aconitate hydratase, mitochondrial n/a
30 Q9X1X7_F3S Q9X1X7 Quinolinate synthase (EC n/a
31 P55038_F3S P55038 Ferredoxin-dependent glutamate synthase n/a
32 A0A3B6UEQ0_F3S A0A3B6UEQ0 hydrogenase (acceptor) (EC n/a
33 Q05755_F3S Q05755 Glutamate synthase [NADPH] n/a
34 P55907_F3S P55907 Zinc-containing ferredoxin-1 n/a
35 P36683_F3S P36683 Aconitate hydratase B n/a
36 Q8ZPH0_F3S Q8ZPH0 Uptake hydrogenase large n/a
37 P49949_F3S P49949 Zinc-containing ferredoxin (Seven-iron n/a
38 Q9BJX6_F3S Q9BJX6 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, n/a
39 A0A0D6G6K3_F3S A0A0D6G6K3 deleted n/a
40 M1VMF7_F3S M1VMF7 Fructose dehydrogenase large n/a
41 P00209_F3S P00209 Ferredoxin-2 (Ferredoxin II) n/a
42 P00364_F3S P00364 Fumarate reductase iron-sulfur n/a
43 O67625_F3S O67625 4-hydroxy-3-methylbut-2-enyl diphosphate reductase n/a
44 E1K247_F3S E1K247 Nickel-dependent hydrogenase large n/a
45 Q8GQE7_F3S Q8GQE7 Glucose dehydrogenase n/a
46 B8YB56_F3S B8YB56 DNA-directed RNA polymerase n/a
47 A0A3B6UEQ1_F3S A0A3B6UEQ1 hydrogenase (acceptor) (EC n/a
48 P21853_F3S P21853 Periplasmic [NiFe] hydrogenase n/a
49 A0A0J1PJ79_F3S A0A0J1PJ79 hydrogenase (acceptor) (EC n/a
50 Q9YHT2_F3S Q9YHT2 Succinate dehydrogenase [ubiquinone] n/a
51 Q2ITY5_F3S Q2ITY5 Putative ferredoxin n/a
52 Q9L869_F3S Q9L869 cytochrome-c3 hydrogenase (EC n/a
53 P0ACE0_F3S P0ACE0 Hydrogenase-2 large chain n/a
54 F2Z6J6_F3S F2Z6J6 Uptake hydrogenase large n/a
55 P00215_F3S P00215 Ferredoxin n/a
56 P69739_F3S P69739 Hydrogenase-1 small chain n/a
57 P17596_F3S P17596 Fumarate reductase iron-sulfur n/a
58 Q0T9N6_F3S Q0T9N6 deleted n/a
59 P71820_F3S P71820 Ferredoxin Fdx n/a
60 P12944_F3S P12944 Periplasmic [NiFe] hydrogenase n/a
61 Q45560_F3S Q45560 Ferredoxin 7Fe (Seven-iron n/a
62 P9WK91_F3S P9WK91 Lipoyl synthase (EC n/a
63 O44074_F3S O44074 Succinate dehydrogenase [ubiquinone] n/a
64 A0QT07_F3S A0QT07 succinate dehydrogenase (EC n/a
65 D3GV55_F3S D3GV55 Succinate dehydrogenase iron-sulfur n/a
66 A0QUM7_F3S A0QUM7 Hydrogenase-2, large subunit n/a
67 A0A076YHN1_F3S A0A076YHN1 Succinate dehydrogenase iron-sulfur n/a
68 Q9X0Z6_F3S Q9X0Z6 [FeFe] hydrogenase maturase n/a
69 P11349_F3S P11349 Respiratory nitrate reductase n/a
70 A0A3B6UEP7_F3S A0A3B6UEP7 hydrogenase (acceptor) (EC n/a
71 T2G9X8_F3S T2G9X8 Fumarate reductase iron-sulfur n/a
72 D3RV26_F3S D3RV26 Uptake hydrogenase large n/a
73 Q9L868_F3S Q9L868 [NiFe] hydrogenase large n/a
74 P31891_F3S P31891 Uptake hydrogenase large n/a
75 P0AC47_F3S P0AC47 Fumarate reductase iron-sulfur n/a
76 P18187_F3S P18187 Periplasmic [NiFe] hydrogenase n/a
77 P62623_F3S P62623 4-hydroxy-3-methylbut-2-enyl diphosphate reductase n/a
78 P21912_F3S P21912 Succinate dehydrogenase [ubiquinone] n/a
79 P95989_F3S P95989 DNA-directed RNA polymerase n/a
80 Q8ZPG9_F3S Q8ZPG9 hydrogenase (acceptor) (EC n/a
81 C5A1E7_F3S C5A1E7 deleted n/a
82 E9AE57_F3S E9AE57 Fumarate hydratase 2 n/a
83 Q5SLI8_F3S Q5SLI8 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase n/a
84 A0A174NUT3_F3S A0A174NUT3 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (EC n/a
85 Q05756_F3S Q05756 Glutamate synthase [NADPH] n/a