Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 6-O-phosphono-beta-D-fructofuranose
PDB ligand accession: F6P
DrugBank: n/a
PubChem: 440641
ChEMBL: CHEMBL604196
InChI Key: BGWGXPAPYGQALX-ARQDHWQXSA-N
SMILES: C(C1C(C(C(O1)(CO)O)O)O)OP(=O)(O)O

ClassyFire chemical classification:

List of proteins that are targets for F6P

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 O60825_F6P O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase n/a
2 P0A993_F6P P0A993 Fructose-1,6-bisphosphatase class 1 n/a
3 P9WN20_F6P P9WN20 Fructose-1,6-bisphosphatase class 2 n/a
4 O32253_F6P O32253 Central glycolytic genes n/a
5 P07953_F6P P07953 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (6PF-2-K/Fru-2,6-P2ase n/a
6 O97193_F6P O97193 fructose-bisphosphatase (EC 3.1.3.11) n/a
7 O32445_F6P O32445 N-acetylglucosamine-6-phosphate deacetylase (GlcNAc n/a
8 Q9N1E2_F6P Q9N1E2 Glucose-6-phosphate isomerase (GPI) n/a
9 O30298_F6P O30298 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase (FBPase/IMPase) (EC n/a
10 P16862_F6P P16862 ATP-dependent 6-phosphofructokinase subunit n/a
11 Q01813_F6P Q01813 ATP-dependent 6-phosphofructokinase, platelet n/a
12 Q07071_F6P Q07071 Glucokinase regulatory protein n/a
13 A0A0E2ZJY0_F6P A0A0E2ZJY0 Fructose-1,6-bisphosphatase n/a
14 Q16875_F6P Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase n/a
15 Q5NFC4_F6P Q5NFC4 Glucose-6-phosphate isomerase (GPI) n/a
16 P00512_F6P P00512 ATP-dependent 6-phosphofructokinase (ATP-PFK) n/a
17 P42861_F6P P42861 Glucose-6-phosphate isomerase (GPI) n/a
18 Q2ADF5_F6P Q2ADF5 deleted n/a
19 P26285_F6P P26285 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase n/a
20 O00757_F6P O00757 Fructose-1,6-bisphosphatase isozyme 2 n/a
21 P16861_F6P P16861 ATP-dependent 6-phosphofructokinase subunit n/a
22 P06999_F6P P06999 ATP-dependent 6-phosphofructokinase isozyme n/a
23 O57693_F6P O57693 NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase n/a
24 A0A117IMA6_F6P A0A117IMA6 alpha,alpha-trehalose-phosphate synthase (ADP-forming) n/a
25 A5U1E6_F6P A5U1E6 Fructose-1,6-bisphosphatase class 2 n/a
26 P17858_F6P P17858 ATP-dependent 6-phosphofructokinase, liver n/a
27 P25081_F6P P25081 Mannose-6-phosphate isomerase (EC n/a
28 P25114_F6P P25114 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (6PF-2-K/Fru-2,6-P2ase n/a
29 Q8ILA4_F6P Q8ILA4 Glucose-6-phosphate isomerase (EC n/a
30 A3N294_F6P A3N294 ABC-type Fe3+ transport n/a
31 Q2FXM8_F6P Q2FXM8 ATP-dependent 6-phosphofructokinase (ATP-PFK) n/a
32 Q04371_F6P Q04371 Damage-control phosphatase YMR027W n/a
33 P00636_F6P P00636 Fructose-1,6-bisphosphatase 1 (FBPase n/a
34 P06745_F6P P06745 Glucose-6-phosphate isomerase (GPI) n/a
35 Q14232_F6P Q14232 Translation initiation factor n/a