Ligand name: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
PDB ligand accession: FK5
DrugBank: DB00864
PubChem: 445643
ChEMBL: CHEMBL269732
InChI Key: QJJXYPPXXYFBGM-LFZNUXCKSA-N
SMILES: CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Phenylpropanoids and polyketides
    • Class: Macrolide lactams
      • Subclass: None

List of proteins that are targets for FK5

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	U3N5X4_FK5	U3N5X4	n/a
2	A5K8X6_FK5	A5K8X6	n/a
3	Q13451_FK5	Q13451	n/a	Ki(nM) = 79.0 Kd(nM) = 104.0
4	J3K9C5_FK5	J3K9C5	n/a
5	P26885_FK5	P26885	n/a
6	A0A0D8JSK0_FK5	A0A0D8JSK0	n/a
7	J3K5Z5_FK5	J3K5Z5	n/a
8	P62942_FK5	P62942	inhibitor	Ki(nM) = 0.4 IC50(nM) = 2.3 Kd(nM) = 0.2
9	Q93ZG9_FK5	Q93ZG9	n/a
10	P48452_FK5	P48452	n/a
11	P45523_FK5	P45523	n/a
12	O94746_FK5	O94746	n/a
13	Q4WUR1_FK5	Q4WUR1	n/a
14	O42773_FK5	O42773	n/a
15	P20081_FK5	P20081	n/a
16	A0A2H4A315_FK5	A0A2H4A315	n/a
17	Q4WDF2_FK5	Q4WDF2	n/a
18	Q6FMA3_FK5	Q6FMA3	n/a
19	Q5SLE7_FK5	Q5SLE7	n/a
20	Q02790_FK5	Q02790	n/a	Kd(nM) = 23.0
21	A0A229WIB4_FK5	A0A229WIB4	n/a
22	P28870_FK5	P28870	n/a
23	J9VL81_FK5	J9VL81	n/a
24	Q4WLV6_FK5	Q4WLV6	n/a
25	Q12306_FK5	Q12306	n/a
26	Q8I4V8_FK5	Q8I4V8	n/a
27	Q00688_FK5	Q00688	n/a
28	P63099_FK5	P63099	n/a
29	C4YS24_FK5	C4YS24	n/a
30	C4YFI3_FK5	C4YFI3	n/a
31	Q3JK38_FK5	Q3JK38	n/a