Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: FARNESYL DIPHOSPHATE
PDB ligand accession: FPP
DrugBank: DB07780
PubChem: 445713
ChEMBL: CHEMBL69330
InChI Key: VWFJDQUYCIWHTN-YFVJMOTDSA-N
SMILES: CC(=CCCC(=CCCC(=CCOP(=O)(O)OP(=O)(O)O)C)C)C

ClassyFire chemical classification:

List of proteins that are targets for FPP

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P14324_FPP P14324 Farnesyl pyrophosphate synthase n/a
2 P49356_FPP P49356 Protein farnesyltransferase subunit n/a
3 T2BPA1_FPP T2BPA1 Protein farnesyltransferase subunit n/a
4 O95749_FPP O95749 Geranylgeranyl pyrophosphate synthase n/a
5 Q8EBR3_FPP Q8EBR3 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
6 Q02293_FPP Q02293 Protein farnesyltransferase subunit n/a
7 Q4WP27_FPP Q4WP27 Protein farnesyltransferase/geranylgeranyltransferase type-1 n/a
8 P60472_FPP P60472 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate n/a
9 Q5RKJ4_FPP Q5RKJ4 Protein farnesyltransferase/geranylgeranyltransferase type-1 n/a
10 Q08602_FPP Q08602 Geranylgeranyl transferase type-2 n/a
11 A0A2Y0TBT9_FPP A0A2Y0TBT9 deleted n/a
12 P53611_FPP P53611 Geranylgeranyl transferase type-2 n/a
13 Q12051_FPP Q12051 Geranylgeranyl pyrophosphate synthase n/a
14 Q40577_FPP Q40577 5-epi-aristolochene synthase (TEAS) n/a
15 Q97SR4_FPP Q97SR4 Isoprenyl transferase (EC n/a
16 Q8DRB3_FPP Q8DRB3 Isoprenyl transferase (EC n/a
17 Q92696_FPP Q92696 Geranylgeranyl transferase type-2 n/a
18 P49354_FPP P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 n/a
19 P08836_FPP P08836 Farnesyl pyrophosphate synthase n/a
20 A0A2P2GK84_FPP A0A2P2GK84 Drimenyl diphosphate synthase n/a
21 J9VSJ6_FPP J9VSJ6 Protein farnesyltransferase/geranylgeranyltransferase type-1 n/a
22 Q04631_FPP Q04631 Protein farnesyltransferase/geranylgeranyltransferase type-1 n/a
23 Q08603_FPP Q08603 Geranylgeranyl transferase type-2 n/a
24 P0A924_FPP P0A924 Phosphatidylglycerophosphatase B (EC n/a
25 A0A5S9I252_FPP A0A5S9I252 Terpene cyclase 6 n/a
26 P60477_FPP P60477 Isoprenyl transferase (EC n/a
27 O53434_FPP O53434 (2Z,6E)-farnesyl diphosphate synthase n/a
28 Q8TPS4_FPP Q8TPS4 Di-trans-poly-cis-decaprenylcistransferase n/a
29 Q9UR08_FPP Q9UR08 Aristolochene synthase (AS) n/a
30 A0A0A0RCB5_FPP A0A0A0RCB5 Sesquisabinene B synthase n/a
31 P01116_FPP P01116 GTPase KRas (EC n/a
32 Q9FT89_FPP Q9FT89 Solanesyl diphosphate synthase n/a
33 Q4WPS9_FPP Q4WPS9 Protein farnesyltransferase subunit n/a