Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: alpha-D-glucopyranose
PDB ligand accession: GLC
DrugBank: n/a
PubChem: 79025
ChEMBL: CHEMBL423707
InChI Key: WQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES: C(C1C(C(C(C(O1)O)O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for GLC

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P37700_GLC P37700 Endoglucanase G (EC n/a
2 P24627_GLC P24627 Lactotransferrin (Lactoferrin) (EC n/a
3 P35247_GLC P35247 Pulmonary surfactant-associated protein n/a
4 P29132_GLC P29132 Enoyl-[acyl-carrier-protein] reductase [NADH] n/a
5 Q92AS9_GLC Q92AS9 beta-glucosidase (EC 3.2.1.21) n/a
6 P02871_GLC P02871 Favin (Lectin) [Cleaved n/a
7 F2L613_GLC F2L613 Trehalose phosphorylase/synthase n/a
8 D6D1V7_GLC D6D1V7 Glycosyl hydrolase family n/a
9 P35557_GLC P35557 Hexokinase-4 (HK4) (EC n/a
10 P01868_GLC P01868 Ig gamma-1 chain n/a
11 P00918_GLC P00918 Carbonic anhydrase 2 n/a
12 Q7X8Q2_GLC Q7X8Q2 Isoamylase n/a
13 A4D2J2_GLC A4D2J2 Hexokinase-4 (HK4) (EC n/a
14 P13807_GLC P13807 Glycogen [starch] synthase, n/a
15 A5ZY13_GLC A5ZY13 Glycosyl hydrolase, family n/a
16 P46976_GLC P46976 Glycogenin-1 (GN-1) (GN1) n/a
17 O08452_GLC O08452 Alpha-amylase (EC 3.2.1.1) n/a
18 A7LXT7_GLC A7LXT7 Xyloglucan-specific endo-beta-1,4-glucanase BoGH5A n/a
19 O33838_GLC O33838 Maltodextrin glycosyltransferase n/a
20 Q9ZFF9_GLC Q9ZFF9 Fap1 adhesin (Adhesin n/a
21 Q07982_GLC Q07982 Glucose--fructose oxidoreductase (GFOR) n/a
22 Q2PS28_GLC Q2PS28 Sucrose isomerase (Trehalulose n/a
23 B6F0T7_GLC B6F0T7 Jacalin-related lectin n/a
24 P00690_GLC P00690 Pancreatic alpha-amylase (PA) n/a
25 Q53Y25_GLC Q53Y25 Phosphotransferase (EC 2.7.1.-) n/a
26 P19367_GLC P19367 Hexokinase-1 (EC 2.7.1.1) n/a
27 P01116-2_GLC P01116-2 n/a
28 Q9KFR4_GLC Q9KFR4 Alpha-amylase G-6 n/a
29 Q7ZA32_GLC Q7ZA32 Pyranose 2-oxidase (EC n/a
30 P0AB91_GLC P0AB91 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive n/a
31 Q8BHN3_GLC Q8BHN3 Neutral alpha-glucosidase AB n/a
32 P13482_GLC P13482 Periplasmic trehalase (EC n/a
33 Q60053_GLC Q60053 Neopullulanase 1 (EC n/a
34 P00490_GLC P00490 Maltodextrin phosphorylase (EC n/a
35 F2E0G2_GLC F2E0G2 Alpha-1,4 glucan phosphorylase n/a
36 Q58999_GLC Q58999 Bifunctional ADP-specific glucokinase/phosphofructokinase n/a
37 A0A077JI83_GLC A0A077JI83 alpha-glucosidase (EC 3.2.1.20) n/a
38 M4SXH7_GLC M4SXH7 Variant surface glycoprotein n/a
39 E7NKU1_GLC E7NKU1 deleted n/a
40 O77811_GLC O77811 Lactotransferrin (Lactoferrin) (EC n/a
41 Q8YWS9_GLC Q8YWS9 beta-fructofuranosidase (EC 3.2.1.26) n/a
42 A0A060SC37_GLC A0A060SC37 Glucose oxidase n/a
43 P11169_GLC P11169 Solute carrier family n/a
44 P10147_GLC P10147 C-C motif chemokine n/a
45 A0A0B5H9B3_GLC A0A0B5H9B3 GH16 family protein n/a
46 Q81G35_GLC Q81G35 Flavodoxin n/a
47 Q7WTR6_GLC Q7WTR6 Cellobiose phosphorylase (EC n/a
48 P00489_GLC P00489 Glycogen phosphorylase, muscle n/a
49 P15056_GLC P15056 Serine/threonine-protein kinase B-raf n/a
50 Q5LC36_GLC Q5LC36 PadR-family transcriptional regulatory n/a
51 U6M598_GLC U6M598 L-lactate dehydrogenase n/a
52 P40943_GLC P40943 Endo-1,4-beta-xylanase (Xylanase) (EC n/a
53 Q9ZEU2_GLC Q9ZEU2 Amylosucrase (EC 2.4.1.4) n/a
54 A9CEY6_GLC A9CEY6 6-dehydroglucose reductase (EC n/a
55 P9WQN9_GLC P9WQN9 Diacylglycerol acyltransferase/mycolyltransferase Ag85C n/a
56 Q2ADF2_GLC Q2ADF2 deleted n/a
57 W7JZC2_GLC W7JZC2 Phosphotransferase (EC 2.7.1.-) n/a
58 Q24368_GLC Q24368 Chromatin-remodeling complex ATPase n/a
59 P36924_GLC P36924 Beta-amylase (EC 3.2.1.2) n/a
60 O15455_GLC O15455 Toll-like receptor 3 n/a
61 E2QP16_GLC E2QP16 D-galactose/methyl-galactoside binding periplasmic n/a
62 D4PEB3_GLC D4PEB3 Endoglucanase FnCel5A (EC n/a
63 Q9LV91_GLC Q9LV91 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic n/a
64 Q9V2Z6_GLC Q9V2Z6 ADP-dependent glucose/glucosamine kinase n/a
65 Q9RE05_GLC Q9RE05 dextransucrase (EC 2.4.1.5) n/a
66 P03472_GLC P03472 Neuraminidase (EC 3.2.1.18) n/a
67 P0AEX9_GLC P0AEX9 Maltose/maltodextrin-binding periplasmic protein n/a
68 Q72KX2_GLC Q72KX2 Probable sugar-binding periplasmic n/a
69 Q00001_GLC Q00001 Rhamnogalacturonase A (RGase n/a
70 O33897_GLC O33897 Cellulase (EC 3.2.1.4) n/a
71 P10538_GLC P10538 Beta-amylase (EC 3.2.1.2) n/a
72 Q9SD76_GLC Q9SD76 Alpha-glucan phosphorylase 2, n/a
73 A0A1E1FFN6_GLC A0A1E1FFN6 beta-glucosidase (EC 3.2.1.21) n/a
74 A9KJS6_GLC A9KJS6 Uncharacterized protein n/a
75 P29563_GLC P29563 Archaerhodopsin-2 (AR 2) n/a
76 F6BL85_GLC F6BL85 Glucosylceramidase (EC 3.2.1.45) n/a
77 Q5SLD7_GLC Q5SLD7 ABC transporter, periplasmic n/a
78 P53051_GLC P53051 Oligo-1,6-glucosidase IMA1 (EC n/a
79 P16218_GLC P16218 Endoglucanase H (EC n/a
80 Q6UVM5_GLC Q6UVM5 Amylosucrase (Sucrose hydrolase) n/a
81 P68871_GLC P68871 Hemoglobin subunit beta n/a
82 P37231_GLC P37231 Peroxisome proliferator-activated receptor n/a
83 O95278_GLC O95278 Laforin (EC 3.1.3.-) n/a
84 P18965_GLC P18965 Factor V activator n/a
85 Q9I3B4_GLC Q9I3B4 HTH hxlR-type domain-containing n/a
86 O58328_GLC O58328 ADP-dependent glucose/glucosamine kinase n/a
87 A6X5L9_GLC A6X5L9 Probable sugar-binding periplasmic n/a
88 P22748_GLC P22748 Carbonic anhydrase 4 n/a
89 P17709_GLC P17709 Glucokinase-1 (EC 2.7.1.2) n/a
90 Q6V8M0_GLC Q6V8M0 Xylanase n/a
91 B3GVK1_GLC B3GVK1 Variant surface glycoprotein n/a
92 Q9V2J8_GLC Q9V2J8 Glycogen synthase n/a
93 A0A1S9DH83_GLC A0A1S9DH83 Alpha-amylase (EC 3.2.1.1) n/a
94 P10253_GLC P10253 Lysosomal alpha-glucosidase (EC n/a
95 A0A6M5K904_GLC A0A6M5K904 Beta-galactosidase n/a
96 Q036L9_GLC Q036L9 Transcriptional regulator, LacI n/a
97 C5RBT0_GLC C5RBT0 Glucose-resistance amylase regulator n/a
98 P02867_GLC P02867 Lectin [Cleaved into: n/a
99 Q9NZD2_GLC Q9NZD2 Glycolipid transfer protein n/a
100 Q9DL16_GLC Q9DL16 Neuraminidase (EC 3.2.1.18) n/a
101 P52790_GLC P52790 Hexokinase-3 (EC 2.7.1.1) n/a
102 Q08129_GLC Q08129 Catalase-peroxidase (CP) (EC n/a
103 P95868_GLC P95868 Glycogen debranching enzyme n/a
104 A0A1U7REJ8_GLC A0A1U7REJ8 Ras-related protein Rab-8A n/a
105 P11217_GLC P11217 Glycogen phosphorylase, muscle n/a
106 P52789_GLC P52789 Hexokinase-2 (EC 2.7.1.1) n/a
107 Q9UJ70_GLC Q9UJ70 N-acetyl-D-glucosamine kinase (N-acetylglucosamine n/a
108 Q5SJN0_GLC Q5SJN0 Mannosylglycerate hydrolase MGH1-like n/a
109 J7HDY4_GLC J7HDY4 Beta-fructofuranosidase n/a
110 Q8ZP84_GLC Q8ZP84 Universal stress protein n/a
111 A0A2I4PGZ0_GLC A0A2I4PGZ0 Beta-glucosidase (EC 3.2.1.21) n/a
112 Q9XEI3_GLC Q9XEI3 Beta-D-glucan exohydrolase isoenzyme n/a
113 P02870_GLC P02870 Lectin [Cleaved into: n/a
114 Q8A1U1_GLC Q8A1U1 beta-glucosidase (EC 3.2.1.21) n/a
115 Q57366_GLC Q57366 Dimethyl sulfoxide/trimethylamine N-oxide n/a
116 B0L7B0_GLC B0L7B0 MalE1 n/a
117 P04745_GLC P04745 Alpha-amylase 1A (EC n/a
118 P10301_GLC P10301 Ras-related protein R-Ras n/a
119 O50271_GLC O50271 ABC transporter substrate-binding n/a
120 P30920_GLC P30920 Cyclomaltodextrin glucanotransferase (EC n/a
121 P24300_GLC P24300 Xylose isomerase (EC n/a
122 B3GVS7_GLC B3GVS7 Variant surface glycoprotein n/a
123 A8CFR3_GLC A8CFR3 Beta-amylase (EC 3.2.1.2) n/a
124 V5SNJ5_GLC V5SNJ5 Glycogen synthase (EC n/a
125 Q7M537_GLC Q7M537 ADP-dependent glucose/glucosamine kinase n/a
126 P23827_GLC P23827 Ecotin n/a
127 W9BQ28_GLC W9BQ28 deleted n/a
128 P0A6U8_GLC P0A6U8 Glycogen synthase (EC n/a
129 Q9ZB17_GLC Q9ZB17 Aldose 1-epimerase (EC n/a
130 Q26609_GLC Q26609 Hexokinase (EC 2.7.1.1) n/a
131 D9MPF2_GLC D9MPF2 Sucrose isomerase n/a
132 P15587_GLC P15587 Xylose isomerase (EC n/a
133 P69905_GLC P69905 Hemoglobin subunit alpha n/a
134 Q9KG76_GLC Q9KG76 Glucan endo-1,3-beta-D-glucosidase (Endo-1,3-beta-glucanase) n/a
135 P42592_GLC P42592 Glucosidase YgjK (EC n/a
136 A0A287SCR5_GLC A0A287SCR5 deleted n/a
137 P04746_GLC P04746 Pancreatic alpha-amylase (PA) n/a
138 Q9ALM8_GLC Q9ALM8 Probable NDP-rhamnosyltransferase n/a
139 S8EY38_GLC S8EY38 Ornithine aminotransferase (EC n/a
140 P0CS93_GLC P0CS93 Galactose oxidase (GAO) n/a
141 P19571_GLC P19571 Glucan 1,4-alpha-maltohexaosidase (EC n/a
142 Q5SRI9_GLC Q5SRI9 Glycoprotein endo-alpha-1,2-mannosidase (Endo-alpha n/a
143 Q8Y4J2_GLC Q8Y4J2 Lmo2446 protein n/a
144 R8KEI7_GLC R8KEI7 deleted n/a
145 P05155_GLC P05155 Plasma protease C1 n/a
146 D4IGH9_GLC D4IGH9 deleted n/a
147 A5FBI2_GLC A5FBI2 Candidate dextranase Glycoside n/a
148 Q9RX51_GLC Q9RX51 Malto-oligosyltrehalose trehalohydrolase (MTHase) n/a
149 P05618_GLC P05618 Cyclomaltodextrin glucanotransferase (EC n/a
150 A0A2D0TC52_GLC A0A2D0TC52 Frutapin n/a
151 P03366_GLC P03366 Gag-Pol polyprotein (Pr160Gag-Pol) n/a
152 P0DTD1_GLC P0DTD1 Replicase polyprotein 1ab n/a
153 E3PQQ9_GLC E3PQQ9 Alpha-L-fucosidase (EC 3.2.1.51) n/a
154 P14769_GLC P14769 N-acetyllactosaminide alpha-1,3-galactosyltransferase (EC n/a
155 Q815J1_GLC Q815J1 Thioredoxin reductase (EC n/a
156 Q9H227_GLC Q9H227 Cytosolic beta-glucosidase (EC n/a
157 P18177_GLC P18177 Toxin B (EC n/a
158 P0AEY0_GLC P0AEY0 Maltose/maltodextrin-binding periplasmic protein n/a
159 P07762_GLC P07762 1,4-alpha-glucan branching enzyme n/a
160 A0A385Z7H9_GLC A0A385Z7H9 Glycosyltransferase (EC 2.4.1.-) n/a
161 K9L8F3_GLC K9L8F3 alpha-amylase (EC 3.2.1.1) n/a
162 P18212_GLC P18212 Oxygen-evolving enhancer protein n/a
163 P17050_GLC P17050 Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) n/a
164 Q8G9Q2_GLC Q8G9Q2 dextransucrase (EC 2.4.1.5) n/a
165 A0A193PKW5_GLC A0A193PKW5 Glycoside hydrolase family n/a
166 O34974_GLC O34974 N-acetyl-S-alkylcysteine sulfoxide monooxygenase n/a
167 P02768_GLC P02768 Albumin n/a
168 P01116_GLC P01116 GTPase KRas (EC n/a
169 P84998_GLC P84998 Glyceraldehyde-3-phosphate dehydrogenase 1 n/a
170 P74325_GLC P74325 sucrose-phosphate phosphatase (EC n/a
171 A7M087_GLC A7M087 deleted n/a
172 A0A024H8G7_GLC A0A024H8G7 GMC oxidoreductase family n/a
173 P07987_GLC P07987 Exoglucanase 2 (EC n/a
174 Q6MIH8_GLC Q6MIH8 ADP-ribose pyrophosphatase (EC n/a
175 Q9QM22_GLC Q9QM22 Protease n/a
176 A0A2Z5V8U8_GLC A0A2Z5V8U8 Jacalin-related lectin n/a
177 Q8VBX4_GLC Q8VBX4 C-type lectin domain n/a
178 A1YIY3_GLC A1YIY3 Antifreeze protein n/a
179 P43379_GLC P43379 Cyclomaltodextrin glucanotransferase (EC n/a
180 P06737_GLC P06737 Glycogen phosphorylase, liver n/a
181 Q0GC07_GLC Q0GC07 Beta-glucosidase (EC 3.2.1.21) n/a
182 P08709_GLC P08709 Coagulation factor VII n/a
183 Q9BPX1_GLC Q9BPX1 L-fucose dehydrogenase (EC n/a
184 Q8L7J2_GLC Q8L7J2 Beta-glucosidase 6 (Os3bglu6) n/a
185 P33284_GLC P33284 Hexokinase (EC 2.7.1.1) n/a
186 M4NKV9_GLC M4NKV9 Glycosylating toxin TcdB n/a
187 P11657_GLC P11657 Major cell-surface adhesin n/a
188 Q48436_GLC Q48436 Diacetyl reductase [(S)-acetoin n/a
189 Q74FS9_GLC Q74FS9 TrkA domain protein n/a
190 D1LZK0_GLC D1LZK0 Beta-D-galactosidase n/a
191 G9NTY1_GLC G9NTY1 Glucanase (EC 3.2.1.-) n/a
192 O32462_GLC O32462 4-alpha-glucanotransferase (EC 2.4.1.25) n/a
193 Q8YQW3_GLC Q8YQW3 Alr3699 protein n/a
194 P08799_GLC P08799 Myosin-2 heavy chain n/a
195 A0A3P8MUS3_GLC A0A3P8MUS3 A-amylase n/a
196 P01556_GLC P01556 Cholera enterotoxin subunit n/a
197 P00725_GLC P00725 Exoglucanase 1 (EC n/a
198 E6UTM3_GLC E6UTM3 deleted n/a