Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: GLUTAMINE
PDB ligand accession: GLN
DrugBank: DB00130
PubChem: 5961;6992086;
ChEMBL: CHEMBL930
InChI Key: ZDXPYRJPNDTMRX-VKHMYHEASA-N
SMILES: C(CC(=O)N)C(C(=O)O)N

ClassyFire chemical classification:

List of proteins that are targets for GLN

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 A0A5D5GA79_GLN A0A5D5GA79 Glutamine synthetase (EC n/a
2 P02911_GLN P02911 Lysine/arginine/ornithine-binding periplasmic protein n/a
3 Q5SIA8_GLN Q5SIA8 CTP synthase (EC n/a
4 P70698_GLN P70698 CTP synthase 1 n/a
5 P53260_GLN P53260 Glutamyl-tRNA(Gln) amidotransferase subunit n/a
6 A0A0F6UK01_GLN A0A0F6UK01 HAMP domain-containing protein n/a
7 Q837U7_GLN Q837U7 Putrescine carbamoyltransferase (PTC) n/a
8 P22262_GLN P22262 Listeriolysin regulatory protein n/a
9 A0A0H2WZ38_GLN A0A0H2WZ38 Lipid II isoglutaminyl n/a
10 Q9CES5_GLN Q9CES5 Glutamine ABC transporter n/a
11 A0A085CCI2_GLN A0A085CCI2 Glutamine synthetase (EC n/a
12 A8JI83_GLN A8JI83 deleted n/a
13 O22822_GLN O22822 UDP-glycosyltransferase 74F2 (EC n/a
14 P00962_GLN P00962 Glutamine--tRNA ligase (EC n/a
15 D9J2T9_GLN D9J2T9 rRNA N-glycosylase (EC n/a
16 Q9VUL1_GLN Q9VUL1 CTP synthase (EC n/a
17 A0A2X0R690_GLN A0A2X0R690 Glutamine transport system n/a
18 N1P8Q8_GLN N1P8Q8 Nta1p n/a
19 A0A173M094_GLN A0A173M094 Taste receptor type n/a
20 P02994_GLN P02994 Elongation factor 1-alpha n/a
21 P12425_GLN P12425 Glutamine synthetase (GS) n/a
22 Q16769_GLN Q16769 Glutaminyl-peptide cyclotransferase (EC n/a
23 P04062_GLN P04062 Lysosomal acid glucosylceramidase n/a
24 A0A0B7LND9_GLN A0A0B7LND9 Lipid II isoglutaminyl n/a
25 Q03164_GLN Q03164 Histone-lysine N-methyltransferase 2A n/a
26 P33893_GLN P33893 Glutamyl-tRNA(Gln) amidotransferase subunit n/a
27 Q9WYV8_GLN Q9WYV8 Release factor glutamine n/a
28 A0A0D6F9Y3_GLN A0A0D6F9Y3 Phosphoribosylformylglycinamidine synthase (FGAM n/a
29 Q03557_GLN Q03557 Glutamyl-tRNA(Gln) amidotransferase subunit n/a
30 P22106_GLN P22106 Asparagine synthetase B n/a
31 Q9RQJ2_GLN Q9RQJ2 Peptidylarginine deiminase (EC n/a
32 Q71RI9_GLN Q71RI9 Kynurenine--oxoglutarate transaminase 3 n/a
33 Q5M4H8_GLN Q5M4H8 Di-or tripeptide:H+ symporter n/a
34 P9WJJ2_GLN P9WJJ2 Glutamine-dependent NAD(+) synthetase n/a
35 V0VBD8_GLN V0VBD8 deleted n/a
36 P09889_GLN P09889 Tartrate-resistant acid phosphatase n/a
37 P37527_GLN P37527 Pyridoxal 5'-phosphate synthase n/a
38 O66610_GLN O66610 Glutamyl-tRNA(Gln) amidotransferase subunit n/a
39 P17812_GLN P17812 CTP synthase 1 antagonist
40 Q15758_GLN Q15758 Neutral amino acid n/a
41 S4TZM6_GLN S4TZM6 Fiber protein n/a
42 C3THM2_GLN C3THM2 Amino acid ABC n/a
43 P27348_GLN P27348 14-3-3 protein theta n/a
44 O59188_GLN O59188 HTH-type transcriptional regulator n/a
45 Q9Z4J8_GLN Q9Z4J8 1,4-beta-N-acetylmuramidase (EC 3.2.1.17, n/a
46 P0A7E5_GLN P0A7E5 CTP synthase (EC n/a
47 Q695T7_GLN Q695T7 Sodium-dependent neutral amino n/a
48 Q9NRF8_GLN Q9NRF8 CTP synthase 2 n/a
49 Q837S0_GLN Q837S0 Amino acid ABC n/a
50 P12296_GLN P12296 Genome polyprotein [Cleaved n/a
51 A0R5M9_GLN A0R5M9 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase n/a
52 A0A173M0G2_GLN A0A173M0G2 Taste receptor, type n/a
53 O94925_GLN O94925 Glutaminase kidney isoform, n/a
54 Q9X0C6_GLN Q9X0C6 Imidazole glycerol phosphate n/a
55 Q972W6_GLN Q972W6 deleted n/a
56 A0A0H2YM47_GLN A0A0H2YM47 Periplasmic dipeptide transport n/a
57 P82610_GLN P82610 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC n/a
58 Q8IJR9_GLN Q8IJR9 GMP synthase [glutamine-hydrolyzing] n/a
59 A0A0F0G8G2_GLN A0A0F0G8G2 Glutamine synthetase (EC n/a
60 P00968_GLN P00968 Carbamoyl phosphate synthase n/a
61 Q9X0C8_GLN Q9X0C8 Imidazole glycerol phosphate n/a
62 P70303_GLN P70303 CTP synthase 2 n/a
63 A0A062WUX3_GLN A0A062WUX3 Lipid II isoglutaminyl n/a
64 P74881_GLN P74881 Phosphoribosylformylglycinamidine synthase (FGAM n/a
65 A0R003_GLN A0R003 Glutamine amidotransferase n/a
66 H8Y6N2_GLN H8Y6N2 CrmG n/a
67 P37528_GLN P37528 Pyridoxal 5'-phosphate synthase n/a
68 P00907_GLN P00907 Carbamoyl phosphate synthase n/a
69 P63488_GLN P63488 Glutamyl-tRNA(Gln) amidotransferase subunit n/a
70 P12821_GLN P12821 Angiotensin-converting enzyme (ACE) n/a
71 E3VXC2_GLN E3VXC2 Glutamine synthetase (EC n/a
72 P08684_GLN P08684 Cytochrome P450 3A4 n/a IC50(nM) = 10000.0