Ligand name: GLUTATHIONE
PDB ligand accession: GSH
DrugBank: DB00143
PubChem: 124886;25246407;171390563;
ChEMBL: CHEMBL1543
InChI Key: RWSXRVCMGQZWBV-WDSKDSINSA-N
SMILES: C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organic acids and derivatives
    • Class: Carboxylic acids and derivatives
      • Subclass: Amino acids, peptides, and analogues

List of proteins that are targets for GSH

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	P30711_GSH	P30711	n/a
2	A0A1S4FIB3_GSH	A0A1S4FIB3	n/a
3	P0CG29_GSH	P0CG29	n/a
4	Q962Y6_GSH	Q962Y6	n/a
5	P81065_GSH	P81065	n/a
6	P28338_GSH	P28338	n/a
7	P08684_GSH	P08684	n/a
8	O35543_GSH	O35543	n/a
9	Q12390_GSH	Q12390	n/a
10	P35754_GSH	P35754	n/a
11	P25373_GSH	P25373	n/a
12	M4MQ92_GSH	M4MQ92	n/a
13	Q9H4Y5_GSH	Q9H4Y5	n/a
14	P41043_GSH	P41043	n/a
15	Q7YT09_GSH	Q7YT09	n/a
16	B8ZLL4_GSH	B8ZLL4	n/a
17	Q9FRL8_GSH	Q9FRL8	n/a
18	Q4WB03_GSH	Q4WB03	n/a
19	Q7JZM3_GSH	Q7JZM3	n/a
20	O60760_GSH	O60760	n/a
21	P10768_GSH	P10768	n/a
22	Q7PVS6_GSH	Q7PVS6	n/a
23	O65032_GSH	O65032	n/a
24	P23202_GSH	P23202	n/a
25	Q28640_GSH	Q28640	n/a
26	P30347_GSH	P30347	n/a
27	V9GZ94_GSH	V9GZ94	n/a
28	A0A0R4I981_GSH	A0A0R4I981	n/a
29	G9B5E4_GSH	G9B5E4	n/a
30	E3Y3H4_GSH	E3Y3H4	n/a
31	P15214_GSH	P15214	n/a
32	Q7JYX0_GSH	Q7JYX0	n/a
33	Q09596_GSH	Q09596	n/a
34	O43813_GSH	O43813	n/a
35	Q16873_GSH	Q16873	n/a
36	A7ILT8_GSH	A7ILT8	n/a
37	Q9N0A4_GSH	Q9N0A4	n/a
38	P68688_GSH	P68688	n/a
39	O14684_GSH	O14684	n/a
40	A0A1W6I4R7_GSH	A0A1W6I4R7	n/a
41	Q25595_GSH	Q25595	n/a
42	Q2G542_GSH	Q2G542	n/a
43	Q84895_GSH	Q84895	n/a
44	A0A1M2V359_GSH	A0A1M2V359	n/a
45	Q3J568_GSH	Q3J568	n/a
46	A6TBY7_GSH	A6TBY7	n/a
47	I6ZUH3_GSH	I6ZUH3	n/a
48	B6TPH0_GSH	B6TPH0	n/a
49	Q4TVQ0_GSH	Q4TVQ0	n/a
50	P19157_GSH	P19157	n/a
51	R7S6N2_GSH	R7S6N2	n/a
52	P77526_GSH	P77526	n/a
53	J9Q529_GSH	J9Q529	n/a
54	A0A3F2YM27_GSH	A0A3F2YM27	n/a
55	Q5CCJ4_GSH	Q5CCJ4	n/a
56	U5GTL0_GSH	U5GTL0	n/a
57	O76003_GSH	O76003	n/a
58	Q9Y5Y6_GSH	Q9Y5Y6	n/a
59	A0A4Y5R087_GSH	A0A4Y5R087	n/a
60	B9HM14_GSH	B9HM14	n/a
61	B4KM86_GSH	B4KM86	n/a
62	A6L2G9_GSH	A6L2G9	n/a
63	Q8F2Y8_GSH	Q8F2Y8	n/a
64	Q5NHD0_GSH	Q5NHD0	n/a
65	P09792_GSH	P09792	n/a
66	Q16772_GSH	Q16772	n/a
67	Q8D0L3_GSH	Q8D0L3	n/a
68	P0AC69_GSH	P0AC69	n/a
69	P0AC59_GSH	P0AC59	n/a
70	Q9WVL0_GSH	Q9WVL0	n/a
71	O30347_GSH	O30347	n/a
72	Q0B681_GSH	Q0B681	n/a
73	A0A384E158_GSH	A0A384E158	n/a
74	P78417_GSH	P78417	n/a
75	Q99828_GSH	Q99828	n/a
76	Q57UN0_GSH	Q57UN0	n/a
77	A8MJH2_GSH	A8MJH2	n/a
78	O14746_GSH	O14746	n/a
79	Q9Y2Q3_GSH	Q9Y2Q3	n/a	IC50(nM) = 20.0
80	P24472_GSH	P24472	n/a
81	Q2YLQ3_GSH	Q2YLQ3	n/a
82	Q4K8I0_GSH	Q4K8I0	n/a
83	Q1GZF4_GSH	Q1GZF4	n/a
84	A5VWI3_GSH	A5VWI3	n/a
85	Q8DRG2_GSH	Q8DRG2	n/a
86	D2X9R3_GSH	D2X9R3	n/a
87	Q5SID2_GSH	Q5SID2	n/a
88	B2TEQ2_GSH	B2TEQ2	n/a
89	Q99735_GSH	Q99735	n/a
90	B9VX79_GSH	B9VX79	n/a
91	P46434_GSH	P46434	n/a
92	C5A7Z5_GSH	C5A7Z5	n/a
93	G0XSZ1_GSH	G0XSZ1	n/a
94	E2PZ87_GSH	E2PZ87	n/a
95	M2R618_GSH	M2R618	n/a
96	Q9I774_GSH	Q9I774	n/a
97	Q5PSJ1_GSH	Q5PSJ1	n/a
98	Q8XVV6_GSH	Q8XVV6	n/a
99	B4E6Q3_GSH	B4E6Q3	n/a
100	P08515_GSH	P08515	n/a
101	P19440_GSH	P19440	n/a
102	Q46845_GSH	Q46845	n/a
103	O18598_GSH	O18598	n/a
104	Q7CQR3_GSH	Q7CQR3	n/a
105	P10620_GSH	P10620	n/a
106	Q86LL8_GSH	Q86LL8	n/a
107	A8R5V3_GSH	A8R5V3	n/a
108	P46439_GSH	P46439	n/a
109	P01899_GSH	P01899	n/a
110	Q9GPL8_GSH	Q9GPL8	n/a
111	A4I8P2_GSH	A4I8P2	n/a
112	O14880_GSH	O14880	n/a
113	Q9FWR4_GSH	Q9FWR4	n/a
114	Q2LKZ0_GSH	Q2LKZ0	n/a
115	Q9NS18_GSH	Q9NS18	n/a
116	A0A8F1AEX2_GSH	A0A8F1AEX2	n/a
117	Q9Y4U1_GSH	Q9Y4U1	n/a
118	B9ICN7_GSH	B9ICN7	n/a
119	M9ZT87_GSH	M9ZT87	n/a
120	Q16775_GSH	Q16775	n/a
121	Q8L7C9_GSH	Q8L7C9	n/a
122	P03950_GSH	P03950	n/a
123	P0AES0_GSH	P0AES0	n/a
124	P13745_GSH	P13745	n/a
125	P03819_GSH	P03819	n/a
126	Q02KA8_GSH	Q02KA8	n/a
127	P20432_GSH	P20432	n/a
128	P09211_GSH	P09211	n/a
129	Q9WXJ9_GSH	Q9WXJ9	n/a
130	P30113_GSH	P30113	n/a
131	Q96SL4_GSH	Q96SL4	n/a	cofactor
132	P17695_GSH	P17695	n/a
133	B9I0G5_GSH	B9I0G5	n/a
134	Q4KDJ6_GSH	Q4KDJ6	n/a
135	O75715_GSH	O75715	n/a	cofactor
136	Q8WVC1_GSH	Q8WVC1	n/a
137	P61626_GSH	P61626	n/a
138	A9PHH6_GSH	A9PHH6	n/a
139	Q51669_GSH	Q51669	n/a
140	B9MWW0_GSH	B9MWW0	n/a
141	B1FXZ2_GSH	B1FXZ2	n/a
142	P46419_GSH	P46419	n/a
143	Q8Z859_GSH	Q8Z859	n/a
144	O49235_GSH	O49235	n/a
145	P09488_GSH	P09488	n/a
146	C8CGT7_GSH	C8CGT7	n/a
147	A0A9E8RZN7_GSH	A0A9E8RZN7	n/a
148	P46427_GSH	P46427	n/a
149	Q04760_GSH	Q04760	n/a	Ki(nM) = 955000.0
150	A1ZB71_GSH	A1ZB71	n/a
151	A5VPS6_GSH	A5VPS6	n/a
152	P36156_GSH	P36156	n/a
153	B0Y813_GSH	B0Y813	n/a
154	C3TEC2_GSH	C3TEC2	n/a
155	P42620_GSH	P42620	n/a
156	Q49SB0_GSH	Q49SB0	n/a
157	P31670_GSH	P31670	n/a
158	D3U1A6_GSH	D3U1A6	n/a
159	Q9GNE9_GSH	Q9GNE9	n/a
160	Q9NP58_GSH	Q9NP58	n/a
161	P08011_GSH	P08011	n/a
162	P00390_GSH	P00390	n/a
163	O80852_GSH	O80852	n/a
164	P14780_GSH	P14780	n/a
165	A3STM0_GSH	A3STM0	n/a
166	O00299_GSH	O00299	n/a
167	Q51948_GSH	Q51948	n/a
168	Q86SX6_GSH	Q86SX6	n/a
169	Q9M9F1_GSH	Q9M9F1	n/a
170	P22217_GSH	P22217	n/a
171	D0LNW1_GSH	D0LNW1	n/a
172	A0A4Y5R032_GSH	A0A4Y5R032	n/a
173	D2WL63_GSH	D2WL63	n/a
174	M2QJS8_GSH	M2QJS8	n/a
175	B1FZ96_GSH	B1FZ96	n/a
176	Q39034_GSH	Q39034	n/a
177	R7S7J5_GSH	R7S7J5	n/a
178	O86043_GSH	O86043	n/a
179	Q99PF4_GSH	Q99PF4	n/a
180	P08263_GSH	P08263	n/a
181	P40416_GSH	P40416	n/a
182	O15247_GSH	O15247	n/a
183	P46436_GSH	P46436	n/a
184	Q8PG02_GSH	Q8PG02	n/a
185	D3U1A5_GSH	D3U1A5	n/a
186	P03952_GSH	P03952	n/a
187	Q9SHH7_GSH	Q9SHH7	n/a
188	Q8YY76_GSH	Q8YY76	n/a
189	Q60CN1_GSH	Q60CN1	n/a
190	B8J605_GSH	B8J605	n/a
191	B9HM36_GSH	B9HM36	n/a
192	H2D5F4_GSH	H2D5F4	n/a
193	B3VQJ7_GSH	B3VQJ7	n/a
194	O50725_GSH	O50725	n/a
195	P30712_GSH	P30712	n/a
196	C5ATQ9_GSH	C5ATQ9	n/a
197	O15217_GSH	O15217	n/a
198	O33374_GSH	O33374	n/a
199	Q9U795_GSH	Q9U795	n/a
200	U5G7B9_GSH	U5G7B9	n/a
201	P0AC62_GSH	P0AC62	n/a
202	A0A1C7D1H4_GSH	A0A1C7D1H4	n/a
203	D3VKV1_GSH	D3VKV1	n/a
204	P30114_GSH	P30114	n/a
205	P0ACA1_GSH	P0ACA1	n/a
206	Q9GN60_GSH	Q9GN60	n/a
207	Q8MU52_GSH	Q8MU52	n/a
208	P78352_GSH	P78352	n/a
209	O33705_GSH	O33705	n/a
210	Q8GWS0_GSH	Q8GWS0	n/a
211	Q81F54_GSH	Q81F54	n/a
212	P15121_GSH	P15121	n/a
213	P21333_GSH	P21333	n/a
214	A0A1P8NWC2_GSH	A0A1P8NWC2	n/a
215	Q7RTV2_GSH	Q7RTV2	n/a
216	P25858_GSH	P25858	n/a
217	P04905_GSH	P04905	n/a
218	Q8N0B3_GSH	Q8N0B3	n/a
219	Q65XA0_GSH	Q65XA0	n/a
220	O88273_GSH	O88273	n/a
221	P41921_GSH	P41921	n/a
222	I0BZV0_GSH	I0BZV0	n/a
223	Q9PE18_GSH	Q9PE18	n/a
224	P16152_GSH	P16152	n/a
225	O43708_GSH	O43708	n/a
226	Q9VGA1_GSH	Q9VGA1	n/a
227	Q03013_GSH	Q03013	n/a
228	P03951_GSH	P03951	n/a
229	Q60860_GSH	Q60860	n/a
230	P28161_GSH	P28161	n/a
231	Q3IZT6_GSH	Q3IZT6	n/a
232	A0A1P8PEY0_GSH	A0A1P8PEY0	n/a
233	O61996_GSH	O61996	n/a
234	D3U1A7_GSH	D3U1A7	n/a
235	A5E437_GSH	A5E437	n/a
236	P04425_GSH	P04425	n/a
237	Q6DH06_GSH	Q6DH06	n/a
238	Q59721_GSH	Q59721	n/a
239	A7JQU5_GSH	A7JQU5	n/a
240	P26697_GSH	P26697	n/a
241	Q7M8V9_GSH	Q7M8V9	n/a
242	P48637_GSH	P48637	n/a
243	Q7P0B4_GSH	Q7P0B4	n/a
244	P24473_GSH	P24473	n/a
245	A0A7M7GUY7_GSH	A0A7M7GUY7	n/a
246	Q12438_GSH	Q12438	n/a
247	Q06A71_GSH	Q06A71	n/a
248	P14141_GSH	P14141	n/a
249	Q88RE7_GSH	Q88RE7	n/a
250	Q9Y316_GSH	Q9Y316	n/a
251	A5EI34_GSH	A5EI34	n/a
252	D0FXZ0_GSH	D0FXZ0	n/a
253	P23907_GSH	P23907	n/a
254	P09210_GSH	P09210	n/a
255	D2YW48_GSH	D2YW48	n/a
256	Q10740_GSH	Q10740	n/a
257	Q9NP99_GSH	Q9NP99	n/a
258	R4S8C5_GSH	R4S8C5	n/a
259	Q9RAF0_GSH	Q9RAF0	n/a
260	Q2G506_GSH	Q2G506	n/a
261	G0SBE6_GSH	G0SBE6	n/a
262	P56598_GSH	P56598	n/a
263	P04818_GSH	P04818	n/a
264	G2IN93_GSH	G2IN93	n/a
265	Q5PY77_GSH	Q5PY77	n/a
266	Q4KED9_GSH	Q4KED9	n/a
267	M5BPX4_GSH	M5BPX4	n/a
268	A0A6I8WFT8_GSH	A0A6I8WFT8	n/a
269	P37231_GSH	P37231	n/a
270	P21266_GSH	P21266	n/a
271	Q4K4R5_GSH	Q4K4R5	n/a
272	A0A384E145_GSH	A0A384E145	n/a
273	P15530_GSH	P15530	n/a
274	P39040_GSH	P39040	n/a
275	Q16875_GSH	Q16875	n/a
276	P32477_GSH	P32477	n/a