Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE
PDB ligand accession: GSP
DrugBank: DB01864
PubChem: 37792;444121;5280465;135398675;135450576;
ChEMBL: CHEMBL1204628
InChI Key: XOFLBQFBSOEHOG-UUOKFMHZSA-N
SMILES: c1nc2c(n1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=S)(O)O)O)O)N=C(NC2=O)N

ClassyFire chemical classification:

List of proteins that are targets for GSP

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P24410_GSP P24410 Ras-related protein Rab-11A n/a
2 P02554_GSP P02554 Tubulin beta chain n/a
3 A0A068C8U8_GSP A0A068C8U8 Rho GTPase Rho1 n/a
4 P01116_GSP P01116 GTPase KRas (EC n/a
5 Q08188_GSP Q08188 Protein-glutamine gamma-glutamyltransferase E n/a
6 P18064_GSP P18064 Guanine nucleotide-binding protein n/a
7 P01112_GSP P01112 GTPase HRas (EC n/a
8 P9WN94_GSP P9WN94 Cell division protein n/a
9 Q24560_GSP Q24560 Tubulin beta-1 chain n/a
10 P61589_GSP P61589 Transforming protein RhoA n/a
11 Q95TD4_GSP Q95TD4 Rho-like small GTPase n/a
12 P15153_GSP P15153 Ras-related C3 botulinum n/a
13 A8IYS5_GSP A8IYS5 Uncharacterized protein n/a
14 P10824_GSP P10824 Guanine nucleotide-binding protein n/a
15 P61586_GSP P61586 Transforming protein RhoA n/a
16 P0A029_GSP P0A029 Cell division protein n/a
17 P64170_GSP P64170 Cell division protein n/a
18 Q9NRW1_GSP Q9NRW1 Ras-related protein Rab-6B n/a
19 P04896_GSP P04896 Guanine nucleotide-binding protein n/a
20 P23258_GSP P23258 Tubulin gamma-1 chain n/a
21 Q9UHD8_GSP Q9UHD8 Septin-9 (MLL septin-like n/a
22 P68105_GSP P68105 Elongation factor 1-alpha n/a
23 P08134_GSP P08134 Rho-related GTP-binding protein n/a
24 Q9UYR9_GSP Q9UYR9 GPN-loop GTPase PAB0955 n/a
25 P04695_GSP P04695 Guanine nucleotide-binding protein n/a
26 P61224_GSP P61224 Ras-related protein Rap-1b n/a
27 A0A146CJG7_GSP A0A146CJG7 Genome polyprotein n/a
28 P27601_GSP P27601 Guanine nucleotide-binding protein n/a
29 Q9D4V7_GSP Q9D4V7 Rab-like protein 3 n/a
30 D4GTC1_GSP D4GTC1 Tubulin-like protein CetZ2 n/a
31 P63000_GSP P63000 Ras-related C3 botulinum n/a
32 Q9UBF8_GSP Q9UBF8 Phosphatidylinositol 4-kinase beta n/a
33 P02550_GSP P02550 Tubulin alpha-1A chain n/a
34 Q1DB04_GSP Q1DB04 Mutual gliding-motility protein n/a
35 G0S8G9_GSP G0S8G9 Eukaryotic translation initiation n/a
36 P01116-2_GSP P01116-2 n/a
37 A0A135VL07_GSP A0A135VL07 GTP-binding protein n/a
38 B5ZA44_GSP B5ZA44 Guanosine pentaphosphate phosphohydrolase n/a
39 P46199_GSP P46199 Translation initiation factor n/a
40 P62491_GSP P62491 Ras-related protein Rab-11A n/a
41 Q57884_GSP Q57884 Probable hydrogenase maturation n/a
42 P68104_GSP P68104 Elongation factor 1-alpha n/a
43 Q2XVP4_GSP Q2XVP4 Tubulin alpha-1B chain n/a
44 Q8KNP3_GSP Q8KNP3 Tubulin-like protein TubZ n/a
45 Q74P24_GSP Q74P24 Tubulin-like protein TubZ n/a
46 P17865_GSP P17865 Cell division protein n/a
47 P62330_GSP P62330 ADP-ribosylation factor 6 n/a