Ligand name: 7,8-DIHYDROBIOPTERIN
PDB ligand accession: HBI
DrugBank: DB04400
PubChem: 119055;5288515;135398687;
ChEMBL: n/a
InChI Key: FEMXZDUTFRTWPE-DZSWIPIPSA-N
SMILES: CC(C(C1=NC2=C(NC1)N=C(NC2=O)N)O)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pteridines and derivatives
      • Subclass: Pterins and derivatives

List of proteins that are targets for HBI

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P22288_HBI	P22288	GTP cyclohydrolase 1	n/a
2	P30047_HBI	P30047	GTP cyclohydrolase 1	n/a
3	Q01782_HBI	Q01782	Pteridine reductase 1	n/a
4	P29476_HBI	P29476	Nitric oxide synthase	n/a
5	P00439_HBI	P00439	Phenylalanine-4-hydroxylase (PAH) (EC	n/a
6	P61457_HBI	P61457	Pterin-4-alpha-carbinolamine dehydratase (PHS)	n/a
7	P61459_HBI	P61459	Pterin-4-alpha-carbinolamine dehydratase (PHS)	n/a
8	P07101_HBI	P07101	Tyrosine 3-monooxygenase (EC	inhibitor
9	P29477_HBI	P29477	Nitric oxide synthase,	n/a
10	O34453_HBI	O34453	Nitric oxide synthase	n/a
11	P30793_HBI	P30793	GTP cyclohydrolase 1	n/a
12	Q93EY3_HBI	Q93EY3	UDP-glucose:tetrahydrobiopterin glucosyltransferase	n/a
13	P30967_HBI	P30967	Phenylalanine-4-hydroxylase (PAH) (EC	n/a
14	Q9U1F8_HBI	Q9U1F8	Pteridine reductase 1	n/a
15	P04177_HBI	P04177	Tyrosine 3-monooxygenase (EC	n/a
16	P70552_HBI	P70552	GTP cyclohydrolase 1	n/a
17	P17752_HBI	P17752	Tryptophan 5-hydroxylase 1	n/a
18	P00378_HBI	P00378	Dihydrofolate reductase (EC	n/a
19	P35228_HBI	P35228	Nitric oxide synthase,	inhibitor
20	Q54XS1_HBI	Q54XS1	Phenylalanine-4-hydroxylase (PAH) (EC	n/a