Ligand name: 4'-HYDROXYCINNAMIC ACID
PDB ligand accession: HC4
DrugBank: DB04066
PubChem: 637542
ChEMBL: CHEMBL66879
InChI Key: NGSWKAQJJWESNS-ZZXKWVIFSA-N
SMILES: c1cc(ccc1C=CC(=O)O)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Phenylpropanoids and polyketides
    • Class: Cinnamic acids and derivatives
      • Subclass: Hydroxycinnamic acids and derivatives

List of proteins that are targets for HC4

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	Q3IWB0_HC4	Q3IWB0	Tyrosine ammonia-lyase (EC	n/a
2	Q39172_HC4	Q39172	NADPH-dependent oxidoreductase 2-alkenal	n/a
3	P80025_HC4	P80025	Lactoperoxidase (LPO) (EC	n/a
4	P68400_HC4	P68400	Casein kinase II	n/a
5	A3K0X1_HC4	A3K0X1	TRAP dicarboxylate transporter,	n/a
6	Q14914_HC4	Q14914	Prostaglandin reductase 1	n/a
7	Q9UQM7_HC4	Q9UQM7	Calcium/calmodulin-dependent protein kinase	n/a	Ki(nM) = 100000.0
8	P16113_HC4	P16113	Photoactive yellow protein	n/a
9	Q9IAT9_HC4	Q9IAT9	Basic phospholipase A2	n/a
10	Q96KB5_HC4	Q96KB5	Lymphokine-activated killer T-cell-originated	n/a
11	Q2IU40_HC4	Q2IU40	Extracellular ligand-binding receptor	n/a
12	O07006_HC4	O07006	Phenolic acid decarboxylase	n/a
13	D0VX11_HC4	D0VX11	Basic phospholipase A2	n/a
14	P01308_HC4	P01308	Insulin [Cleaved into:	n/a
15	Q7X0D9_HC4	Q7X0D9	Repressor protein	n/a
16	Q94FV7_HC4	Q94FV7	Polyketide synthase BAS	n/a
17	A0A1D3S5H0_HC4	A0A1D3S5H0	Carboxylic ester hydrolase	n/a
18	E0TW95_HC4	E0TW95	Transcriptional regulator	n/a
19	Q1R0W5_HC4	Q1R0W5	TRAP dicarboxylate transporter-DctP	n/a
20	Q9X2W8_HC4	Q9X2W8	Photoactive yellow protein	n/a
21	Q6N8W4_HC4	Q6N8W4	ABC transporter substrate-binding	n/a