Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: MERCURY (II) ION
PDB ligand accession: HG
DrugBank: n/a
PubChem: 26623
ChEMBL: n/a
InChI Key: BQPIGGFYSBELGY-UHFFFAOYSA-N
SMILES: [Hg+2]

ClassyFire chemical classification:

List of proteins that are targets for HG

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q29551_HG Q29551 Succinyl-CoA:3-ketoacid coenzyme A n/a
2 P43591_HG P43591 ATP-dependent kinase YFH7 n/a
3 O00213_HG O00213 Amyloid beta precursor n/a
4 Q9WVG6_HG Q9WVG6 Histone-arginine methyltransferase CARM1 n/a
5 H0QD82_HG H0QD82 deleted n/a
6 P00282_HG P00282 Azurin n/a
7 P08575_HG P08575 Receptor-type tyrosine-protein phosphatase n/a
8 Q5ZSD5_HG Q5ZSD5 SidF, inhibitor of n/a
9 P44096_HG P44096 UPF0234 protein HI_1034 n/a
10 Q9X180_HG Q9X180 histidine kinase (EC n/a
11 P40919_HG P40919 Imidazoleglycerol-phosphate dehydratase (IGPD) n/a
12 P14925_HG P14925 Peptidylglycine alpha-amidating monooxygenase n/a
13 Q9Y6E0_HG Q9Y6E0 Serine/threonine-protein kinase 24 n/a
14 O43583_HG O43583 Density-regulated protein (DRP) n/a
15 P11387_HG P11387 DNA topoisomerase 1 n/a
16 P07584_HG P07584 Astacin (EC 3.4.24.21) n/a
17 P03315_HG P03315 Structural polyprotein (p130) n/a
18 P10845_HG P10845 Botulinum neurotoxin type n/a
19 Q5P5G4_HG Q5P5G4 Acetophenone carboxylase gamma n/a
20 Q8XMB9_HG Q8XMB9 Probable transcriptional regulator n/a
21 A1E8I9_HG A1E8I9 Alkene reductase (N-ethylmaleimide n/a
22 Q72HW2_HG Q72HW2 Laccase (EC 1.10.3.2) n/a
23 C3SU37_HG C3SU37 Undecaprenyl-diphosphatase (EC 3.6.1.27) n/a
24 Q56185_HG Q56185 (S)-2-hydroxypropylphosphonic acid epoxidase n/a
25 Q799U3_HG Q799U3 Mercuric resistance operon n/a
26 P54841_HG P54841 Transcription factor MafB n/a
27 Q8TZJ1_HG Q8TZJ1 Serine aminopeptidase S33 n/a
28 P03772_HG P03772 Serine/threonine-protein phosphatase (EC n/a
29 O28163_HG O28163 3-methyladenine DNA glycosylase n/a
30 P77522_HG P77522 Iron-sulfur cluster assembly n/a
31 P33895_HG P33895 Kinetochore protein NUF2 n/a
32 E2GHW2_HG E2GHW2 GH26 endo-beta-1,4-mannanase (EC n/a
33 Q9KS51_HG Q9KS51 Multidrug resistance protein, n/a
34 P0A9G6_HG P0A9G6 Isocitrate lyase (ICL) n/a
35 Q56310_HG Q56310 Chemotaxis protein CheA n/a
36 P9WME7_HG P9WME7 Uncharacterized HTH-type transcriptional n/a
37 P0A1I3_HG P0A1I3 Invasion protein InvA n/a
38 P34232_HG P34232 mRNA transport regulator n/a
39 P09803_HG P09803 Cadherin-1 (ARC-1) (Epithelial n/a
40 P04955_HG P04955 Endoglucanase A (EGA) n/a
41 Q8GF99_HG Q8GF99 TcdB2 n/a
42 Q9NLB2_HG Q9NLB2 Glutaredoxin-1 n/a
43 Q5ZJ86_HG Q5ZJ86 Uncharacterized protein n/a
44 P38636_HG P38636 Copper chaperone ATX1 n/a
45 Q1I8U1_HG Q1I8U1 Monalysin (beta-barrel pore-forming n/a
46 P45314_HG P45314 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase n/a
47 P49917_HG P49917 DNA ligase 4 n/a
48 Q72GS0_HG Q72GS0 NAD(P) transhydrogenase subunit n/a
49 B3Y018_HG B3Y018 Tannase n/a
50 A0A380PV03_HG A0A380PV03 Transporter, sodium/bile acid n/a
51 P40014_HG P40014 Kinetochore protein SPC25 n/a
52 Q9S3V1_HG Q9S3V1 Flavin-dependent L-tryptophan oxidase n/a
53 P06873_HG P06873 Proteinase K (EC n/a
54 Q7SIF4_HG Q7SIF4 Arsenite oxidase subunit n/a
55 Q07794_HG Q07794 Histone acetyltransferase RTT109 n/a
56 P17778_HG P17778 Outer membrane protein n/a
57 Q7SIF3_HG Q7SIF3 Arsenite oxidase subunit n/a
58 Q9Y6N7_HG Q9Y6N7 Roundabout homolog 1 n/a
59 P00299_HG P00299 Plastocyanin A, chloroplastic n/a
60 Q8C570_HG Q8C570 mRNA export factor n/a
61 P25910_HG P25910 Metallo-beta-lactamase type 2 n/a
62 O94556_HG O94556 Anaphase-promoting complex subunit n/a
63 P54288_HG P54288 Voltage-dependent L-type calcium n/a
64 P00378_HG P00378 Dihydrofolate reductase (EC n/a
65 Q12125_HG Q12125 Golgi to ER n/a
66 Q9HYQ4_HG Q9HYQ4 Probable transcriptional regulator n/a
67 A6X980_HG A6X980 Transcription factor tau n/a
68 A0A143ZZR8_HG A0A143ZZR8 Plasmodium RESA N-terminal n/a
69 Q9DU47_HG Q9DU47 Genome polyprotein n/a
70 O67077_HG O67077 ATP-dependent zinc metalloprotease n/a
71 A8JF99_HG A8JF99 Uncharacterized protein n/a
72 Q72GR9_HG Q72GR9 proton-translocating NAD(P)(+) transhydrogenase n/a
73 P29082_HG P29082 Sulfur oxygenase/reductase (EC n/a
74 Q195N6_HG Q195N6 Pyruvate, phosphate dikinase n/a
75 A0LNN5_HG A0LNN5 L-lactate transporter (SfMCT) n/a
76 O14229_HG O14229 Transcription factor tau n/a
77 Q12904_HG Q12904 Aminoacyl tRNA synthase n/a
78 P23873_HG P23873 Antitoxin HipB n/a
79 P04043_HG P04043 Type II methyltransferase n/a
80 P04129_HG P04129 Mercuric transport protein n/a
81 P35968_HG P35968 Vascular endothelial growth n/a
82 Q9GRG6_HG Q9GRG6 6-phosphogluconolactonase (6PGL) (EC n/a
83 P00394_HG P00394 5,10-methylenetetrahydrofolate reductase (MTHFR) n/a
84 Q07879_HG Q07879 Ubiquitin-like-conjugating enzyme ATG10 n/a
85 Q01738_HG Q01738 Cellobiose dehydrogenase (CDH) n/a
86 Q8VP84_HG Q8VP84 Anthranilate phosphoribosyltransferase (EC n/a
87 Q9Z2L7_HG Q9Z2L7 Cytokine receptor-like factor n/a
88 T2B7E1_HG T2B7E1 Ferritin (EC 1.16.3.1) n/a
89 Q9VKM1_HG Q9VKM1 Protein piwi (EC n/a
90 P17501_HG P17501 Major envelope glycoprotein n/a
91 P37552_HG P37552 2-iminobutanoate/2-iminopropanoate deaminase (EC n/a
92 Q6ICB0_HG Q6ICB0 Desumoylating isopeptidase 1 n/a
93 Q5P5G5_HG Q5P5G5 Acetophenone carboxylase delta n/a
94 P02699_HG P02699 Rhodopsin n/a
95 P00573_HG P00573 T7 RNA polymerase n/a
96 Q70LE6_HG Q70LE6 Uncharacterized protein ORF157 n/a
97 O95786_HG O95786 Antiviral innate immune n/a
98 O75015_HG O75015 Low affinity immunoglobulin n/a
99 Q236S9_HG Q236S9 NAD(P)(+)--arginine ADP-ribosyltransferase (EC n/a
100 P40336_HG P40336 Vacuolar protein sorting-associated n/a
101 P49723_HG P49723 Ribonucleoside-diphosphate reductase small n/a
102 Q6RCR4_HG Q6RCR4 SidC n/a
103 O87172_HG O87172 4-alpha-glucanotransferase (EC 2.4.1.25) n/a
104 Q9X592_HG Q9X592 Pectate lyase n/a
105 Q846V4_HG Q846V4 Staphylocoagulase n/a
106 Q7VYU0_HG Q7VYU0 Fluoride-specific ion channel n/a
107 P27487_HG P27487 Dipeptidyl peptidase 4 n/a
108 P16442_HG P16442 Histo-blood group ABO n/a
109 P07102_HG P07102 Phytase AppA (EC n/a
110 Q6D8U3_HG Q6D8U3 Zinc protease n/a
111 P03355_HG P03355 Gag-Pol polyprotein (Pr180gag-pol) n/a
112 O60341_HG O60341 Lysine-specific histone demethylase n/a
113 O30989_HG O30989 Response regulatory protein n/a
114 P05460_HG P05460 Polarity suppression protein n/a
115 P44007_HG P44007 S-ribosylhomocysteine lyase (EC n/a
116 P49137_HG P49137 MAP kinase-activated protein n/a
117 P06276_HG P06276 Cholinesterase (EC 3.1.1.8) n/a
118 P00690_HG P00690 Pancreatic alpha-amylase (PA) n/a
119 Q8DJT8_HG Q8DJT8 Protein Thf1 n/a
120 P77072_HG P77072 Alkylmercury lyase (EC n/a
121 P59641_HG P59641 Replicase polyprotein 1a n/a
122 Q41372_HG Q41372 Aquaporin n/a
123 Q8KND2_HG Q8KND2 CalO6 n/a
124 P43005_HG P43005 Excitatory amino acid n/a
125 P30328_HG P30328 Major capsid protein n/a
126 P08172_HG P08172 Muscarinic acetylcholine receptor n/a
127 P77689_HG P77689 Iron-sulfur cluster assembly n/a
128 Q6FI81_HG Q6FI81 Anamorsin (Cytokine-induced apoptosis n/a
129 Q6ST21_HG Q6ST21 N-acetyl-beta-D-glucosaminidase (EC 3.2.1.52) n/a
130 Q2JJF6_HG Q2JJF6 Vitamin K epoxide n/a
131 Q9LCZ4_HG Q9LCZ4 ATP-dependent zinc metalloprotease n/a
132 P03018_HG P03018 DNA helicase II n/a
133 P02920_HG P02920 Lactose permease (Lactose-proton n/a
134 A3DN96_HG A3DN96 IPT/TIG domain-containing protein n/a
135 Q9K499_HG Q9K499 Epi-isozizaene synthase (EIZS) n/a
136 P76541_HG P76541 Bacterial microcompartment shell n/a
137 Q01217_HG Q01217 Protein ARG5,6, mitochondrial n/a
138 P44920_HG P44920 Dephospho-CoA kinase (EC n/a
139 P75838_HG P75838 Ribosomal protein S12 n/a
140 Q9NPI8_HG Q9NPI8 Fanconi anemia group n/a
141 Q52546_HG Q52546 Replication protein n/a
142 P10056_HG P10056 Caricain (EC 3.4.22.30) n/a
143 Q6RCR0_HG Q6RCR0 SdeA n/a
144 Q8NBP7_HG Q8NBP7 Proprotein convertase subtilisin/kexin n/a
145 P0AAC8_HG P0AAC8 Iron-binding protein IscA n/a
146 P60844_HG P60844 Aquaporin Z (Bacterial n/a
147 Q63GK8_HG Q63GK8 Protein-N(Pi)-phosphohistidine-sugar phosphotransferase (Enzyme n/a
148 O18423_HG O18423 Lysenin (Beta-barrel pore-forming n/a
149 Q5I1Y5_HG Q5I1Y5 ATP-dependent translocase ABCB1 n/a
150 Q96C10_HG Q96C10 ATP-dependent RNA helicase n/a
151 P00730_HG P00730 Carboxypeptidase A1 (EC n/a
152 P00273_HG P00273 Desulforedoxin (DX) n/a
153 P61769_HG P61769 Beta-2-microglobulin [Cleaved into: n/a
154 P27150_HG P27150 Large ribosomal subunit n/a
155 P21447_HG P21447 ATP-dependent translocase ABCB1 n/a
156 O59010_HG O59010 Glutamate transporter homolog n/a
157 P0A1K1_HG P0A1K1 Flagellar FliJ protein n/a
158 P00760_HG P00760 Serine protease 1 n/a
159 P14769_HG P14769 N-acetyllactosaminide alpha-1,3-galactosyltransferase (EC n/a
160 P00918_HG P00918 Carbonic anhydrase 2 n/a
161 A7U483_HG A7U483 Cytochrome P450 17A2 n/a
162 P31553_HG P31553 L-carnitine/gamma-butyrobetaine antiporter n/a
163 Q9X220_HG Q9X220 Probable tRNA sulfurtransferase n/a
164 Q5FNR0_HG Q5FNR0 Putative oxidoreductase n/a
165 Q9AIP9_HG Q9AIP9 Surface-associated protein n/a
166 P28790_HG P28790 3-ketoacyl-CoA thiolase (EC n/a
167 P04287_HG P04287 D-alanyl-D-alanine carboxypeptidase DacA n/a
168 Q72GM3_HG Q72GM3 Leucine--tRNA ligase (EC n/a
169 Q7SIE4_HG Q7SIE4 Leucine--tRNA ligase (EC n/a
170 P04296_HG P04296 Major DNA-binding protein n/a
171 O81192_HG O81192 (+)-bornyl diphosphate synthase, n/a
172 P15873_HG P15873 Proliferating cell nuclear n/a
173 D0MDR1_HG D0MDR1 ABC-type uncharacterized transport n/a
174 O70239_HG O70239 Axin-1 (Axis inhibition n/a
175 B0RTN2_HG B0RTN2 Uncharacterized protein n/a
176 P05373_HG P05373 Delta-aminolevulinic acid dehydratase n/a
177 P02794_HG P02794 Ferritin heavy chain n/a
178 P18891_HG P18891 Fucose-specific lectin (Aleuria n/a
179 E7CWP5_HG E7CWP5 Envelope glycoprotein gp160 n/a
180 D3PQC9_HG D3PQC9 CRISPR-associated protein, Cse2 n/a
181 Q97XQ5_HG Q97XQ5 Helicase of the n/a
182 P23874_HG P23874 Serine/threonine-protein kinase toxin n/a
183 A0A0M3KKW3_HG A0A0M3KKW3 Phospholipase A1 (vPLA1) n/a
184 Q9ES28_HG Q9ES28 Rho guanine nucleotide n/a
185 P16157_HG P16157 Ankyrin-1 (ANK-1) (Ankyrin-R) n/a
186 O60741_HG O60741 Potassium/sodium hyperpolarization-activated cyclic n/a
187 P44583_HG P44583 N-acetylneuraminate anomerase (N-acetylneuraminate n/a
188 P04292_HG P04292 DNA polymerase catalytic n/a
189 Q26490_HG Q26490 Retinol dehydratase n/a
190 P62988_HG P62988 Ubiquitin-ribosomal protein eS31 n/a
191 Q70V27_HG Q70V27 Histo-blood group ABO n/a
192 P29283_HG P29283 Global nitrogen regulator n/a
193 Q02060_HG Q02060 Photosystem II 22 n/a
194 Q6ISD4_HG Q6ISD4 Histo-blood group ABO n/a
195 P0ABU8_HG P0ABU8 Biopolymer transport protein n/a
196 P44492_HG P44492 tRNA threonylcarbamoyladenosine biosynthesis n/a
197 P35729_HG P35729 Nucleoporin NUP120 (Nuclear n/a
198 A3DGR1_HG A3DGR1 Transcriptional regulator, PadR-like n/a
199 Q9K0A9_HG Q9K0A9 Transporter n/a
200 P0A183_HG P0A183 Mercuric resistance operon n/a
201 Q8N5J2_HG Q8N5J2 Ubiquitin carboxyl-terminal hydrolase n/a
202 O58799_HG O58799 342aa long hypothetical n/a
203 P00392_HG P00392 Mercuric reductase (EC n/a
204 Q7DJN2_HG Q7DJN2 MerB2 n/a
205 Q9UHD2_HG Q9UHD2 Serine/threonine-protein kinase TBK1 n/a
206 D6R8X8_HG D6R8X8 Hydantoin permease (MHP) n/a
207 Q8W4L5_HG Q8W4L5 B3 domain-containing transcription n/a
208 O50407_HG O50407 Tuberculosinyl adenosine transferase n/a
209 P97929_HG P97929 Breast cancer type n/a
210 A0A0B5GUS3_HG A0A0B5GUS3 Calcium binding protein n/a
211 P40460_HG P40460 Kinetochore protein NDC80 n/a
212 Q9I685_HG Q9I685 Adenosylhomocysteinase (EC 3.13.2.1) n/a
213 P00806_HG P00806 Endolysin (EC 3.5.1.28) n/a
214 O67049_HG O67049 Shikimate dehydrogenase (NADP(+)) n/a
215 P69924_HG P69924 Ribonucleoside-diphosphate reductase 1 n/a
216 Q9D1F3_HG Q9D1F3 Protein EOLA1 (Endothelial-overexpressed n/a
217 A0R3F9_HG A0R3F9 Acetyltransferase Pat (EC n/a
218 P41277_HG P41277 Glycerol-1-phosphate phosphohydrolase 1 n/a
219 Q9KVB4_HG Q9KVB4 Capsular polysaccharide biosynthesis n/a
220 P0A805_HG P0A805 Ribosome-recycling factor (RRF) n/a
221 Q9Y616_HG Q9Y616 Interleukin-1 receptor-associated kinase n/a
222 Q9H3F6_HG Q9H3F6 BTB/POZ domain-containing adapter n/a
223 P11277_HG P11277 Spectrin beta chain, n/a
224 Q9FCA6_HG Q9FCA6 Biflaviolin synthase CYP158A2 n/a
225 P00915_HG P00915 Carbonic anhydrase 1 n/a
226 P84141_HG P84141 Chondroitinase (Chondroitin lyase) n/a
227 P69380_HG P69380 Cation-efflux pump FieF n/a
228 I1ZTN7_HG I1ZTN7 deleted n/a
229 P9WIR7_HG P9WIR7 Alanine and proline-rich n/a
230 Q4H436_HG Q4H436 Laccase-like protein n/a
231 Q7N8J0_HG Q7N8J0 Photorhabdus luminescens subsp. n/a
232 P75906_HG P75906 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase (PGA n/a
233 O14188_HG O14188 Ras GTPase-activating-like protein n/a
234 P04058_HG P04058 Acetylcholinesterase (AChE) (EC n/a
235 Q5P5G3_HG Q5P5G3 Acetophenone carboxylase beta n/a
236 D7VA33_HG D7VA33 deleted n/a
237 Q01532_HG Q01532 Cysteine proteinase 1, n/a
238 Q59976_HG Q59976 Beta-glucosidase (EC 3.2.1.21) n/a
239 Q6NYC1_HG Q6NYC1 Bifunctional arginine demethylase n/a
240 Q99538_HG Q99538 Legumain (EC 3.4.22.34) n/a
241 P15879_HG P15879 Mono-ADP-ribosyltransferase C3 (EC n/a
242 P30750_HG P30750 Methionine import ATP-binding n/a
243 Q9BUQ8_HG Q9BUQ8 Probable ATP-dependent RNA n/a
244 Q57ZF2_HG Q57ZF2 Mitochondrial RNA binding n/a
245 O00244_HG O00244 Copper transport protein n/a
246 Q7L5N1_HG Q7L5N1 COP9 signalosome complex n/a
247 P07773_HG P07773 Catechol 1,2-dioxygenase (EC n/a
248 P07992_HG P07992 DNA excision repair n/a
249 Q9HUH4_HG Q9HUH4 Probable FAD-dependent oxidoreductase n/a
250 P39332_HG P39332 RutC family protein n/a
251 P60932_HG P60932 Undecaprenyl-diphosphatase (EC 3.6.1.27) n/a
252 Q79V61_HG Q79V61 Circadian clock oscillator n/a
253 Q60352_HG Q60352 Isopentenyl phosphate kinase n/a
254 P61823_HG P61823 Ribonuclease pancreatic (EC n/a
255 Q9HU77_HG Q9HU77 Formimidoylglutamate deiminase (EC n/a
256 P00974_HG P00974 Pancreatic trypsin inhibitor n/a
257 Q2NKJ3_HG Q2NKJ3 CST complex subunit n/a
258 P69488_HG P69488 Divalent-cation tolerance protein n/a
259 B1L3C9_HG B1L3C9 Acyl-CoA synthetase (NDP n/a
260 P00734_HG P00734 Prothrombin (EC 3.4.21.5) n/a
261 P00268_HG P00268 Rubredoxin (Rd) n/a
262 Q39583_HG Q39583 Membrane protein n/a
263 A8JEA1_HG A8JEA1 deleted n/a
264 C9QXS7_HG C9QXS7 deleted n/a
265 Q9X1B7_HG Q9X1B7 Phosphatidate cytidylyltransferase (EC n/a
266 Q5L4B1_HG Q5L4B1 Nonstructural protein n/a
267 Q7NDN8_HG Q7NDN8 Proton-gated ion channel n/a
268 Q9RX48_HG Q9RX48 DNA-directed DNA polymerase n/a
269 P45202_HG P45202 Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK n/a
270 P25746_HG P25746 High frequency lysogenization n/a
271 P54309_HG P54309 Portal protein (Gene n/a
272 Q9Y7P0_HG Q9Y7P0 Riboflavin synthase (RS) n/a
273 P28692_HG P28692 Ribosomal RNA large n/a
274 Q9HLD9_HG Q9HLD9 CBS domain-containing protein n/a
275 Q95YI4_HG Q95YI4 Luciferin regenerating enzyme n/a