Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid
PDB ligand accession: IM2
DrugBank: n/a
PubChem: 5288621
ChEMBL: n/a
InChI Key: UACUABDJLSUFFC-IWSPIJDZSA-N
SMILES: CC(C(C=O)C1CC(=C(N1)C(=O)O)SCCNC=N)O

ClassyFire chemical classification:

List of proteins that are targets for IM2

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q09HD0_IM2 Q09HD0 Beta-lactamase GES-5 (EC n/a
2 Q51400_IM2 Q51400 Beta-lactamase (EC 3.5.2.6) n/a
3 Q9XB24_IM2 Q9XB24 Beta-lactamase (EC 3.5.2.6) n/a
4 Q9KJY7_IM2 Q9KJY7 Beta-lactamase GES-1 (EC n/a
5 V5TGX0_IM2 V5TGX0 beta-lactamase (EC 3.5.2.6) n/a
6 O34816_IM2 O34816 Putative L,D-transpeptidase YkuD n/a
7 P62593_IM2 P62593 Beta-lactamase TEM (EC n/a
8 P39045_IM2 P39045 D-alanyl-D-alanine carboxypeptidase (DD-carboxypeptidase) n/a
9 Q7WU28_IM2 Q7WU28 Beta-lactam sensor/signal transducer n/a
10 F6KZJ2_IM2 F6KZJ2 Beta-lactamase (EC 3.5.2.6) n/a
11 I6Y9J2_IM2 I6Y9J2 L,D-transpeptidase 2 (LDT n/a
12 Q7BNC2_IM2 Q7BNC2 Beta-lactamase (EC 3.5.2.6) n/a
13 P0AEB2_IM2 P0AEB2 D-alanyl-D-alanine carboxypeptidase DacA n/a
14 G1C794_IM2 G1C794 Penicillin-binding protein 1A n/a
15 Q9K3C9_IM2 Q9K3C9 PBP4 protein (Penicillin-binding n/a
16 Q9F663_IM2 Q9F663 Carbapenem-hydrolyzing beta-lactamase KPC-2 n/a
17 A0A075Q0W3_IM2 A0A075Q0W3 Pbp5 n/a
18 Q6XEC0_IM2 Q6XEC0 Beta-lactamase OXA-48 (EC n/a
19 L0T5Q5_IM2 L0T5Q5 L,D-transpeptidase 1 (LDT n/a
20 Q93PQ0_IM2 Q93PQ0 Beta-lactamase (EC 3.5.2.6) n/a
21 P00811_IM2 P00811 Beta-lactamase (EC 3.5.2.6) n/a
22 Q0Z8S4_IM2 Q0Z8S4 beta-lactamase (EC 3.5.2.6) n/a
23 P71586_IM2 P71586 Peptidoglycan D,D-transpeptidase PbpA n/a
24 Q51504_IM2 Q51504 Peptidoglycan D,D-transpeptidase FtsI n/a