Ligand name: INDOMETHACIN
PDB ligand accession: IMN
DrugBank: DB00328
PubChem: 3715
ChEMBL: CHEMBL6
InChI Key: CGIGDMFJXJATDK-UHFFFAOYSA-N
SMILES: Cc1c(c2cc(ccc2n1C(=O)c3ccc(cc3)Cl)OC)CC(=O)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Indoles and derivatives
      • Subclass: Benzoylindoles

List of proteins that are targets for IMN

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	Q8N8N7_IMN	Q8N8N7	inhibitor
2	Q9N0A4_IMN	Q9N0A4	n/a
3	P35354_IMN	P35354	inhibitor	Ki(nM) = 130.0 IC50(nM) = 0.14 Kd(nM) = 92.0
4	Q04760_IMN	Q04760	inhibitor	Ki(nM) = 18100.0
5	Q9EQZ5_IMN	Q9EQZ5	n/a
6	P02768_IMN	P02768	n/a	Ki(nM) = 15100.0 Kd(nM) = 700.0
7	Q9Y5Y4_IMN	Q9Y5Y4	other/unknown	Ki(nM) = 50.0 EC50(nM) = 389.0
8	P37231_IMN	P37231	activator	EC50(nM) = 50000.0
9	P05543_IMN	P05543	n/a
10	Q05769_IMN	Q05769	n/a	IC50(nM) = 6.4
11	P24627_IMN	P24627	n/a
12	P05413_IMN	P05413	n/a
13	P52895_IMN	P52895	n/a	Ki(nM) = 100000.0 IC50(nM) = 8970.0
14	P59071_IMN	P59071	n/a
15	P42330_IMN	P42330	inhibitor	Ki(nM) = 270.0 IC50(nM) = 100.0
16	P23219_IMN	P23219	inhibitor	Ki(nM) = 13.0 IC50(nM) = 0.14 Kd(nM) = 253.0
17	P02766_IMN	P02766	n/a
18	Q07869_IMN	Q07869	agonist
19	P14555_IMN	P14555	inhibitor
20	P19525_IMN	P19525	inducer
21	D0VX11_IMN	D0VX11	n/a