Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE
PDB ligand accession: IPE
DrugBank: DB04714
PubChem: 1195
ChEMBL: CHEMBL356362
InChI Key: NUHSROFQTUXZQQ-UHFFFAOYSA-N
SMILES: CC(=C)CCOP(=O)(O)OP(=O)(O)O

ClassyFire chemical classification:

List of proteins that are targets for IPE

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P60472_IPE P60472 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate n/a
2 P60479_IPE P60479 Decaprenyl diphosphate synthase n/a
3 Q9HLX1_IPE Q9HLX1 Isopentenyl phosphate kinase n/a
4 O00481_IPE O00481 Butyrophilin subfamily 3 n/a
5 A5K4U6_IPE A5K4U6 Farnesyl pyrophosphate synthase, n/a
6 P22939_IPE P22939 Farnesyl diphosphate synthase n/a
7 P14324_IPE P14324 Farnesyl pyrophosphate synthase inhibitor
8 P61615_IPE P61615 Isopentenyl-diphosphate delta-isomerase (IPP n/a
9 A0A0F8R9A0_IPE A0A0F8R9A0 Dihydroorotate dehydrogenase (Undecaprenyl n/a
10 B9DUT7_IPE B9DUT7 Geranyltranstransferase (EC 2.5.1.10) n/a
11 A0A348FUE1_IPE A0A348FUE1 Copalyl diphosphate synthase n/a
12 Q9SBR3_IPE Q9SBR3 Geranyl diphosphate synthase n/a
13 Q4QBL1_IPE Q4QBL1 Farnesyl pyrophosphate synthase n/a
14 Q8WS26_IPE Q8WS26 Farnesyl diphosphate synthase n/a
15 O95749_IPE O95749 Geranylgeranyl pyrophosphate synthase n/a
16 K0BUH0_IPE K0BUH0 deleted n/a
17 Q1XAB1_IPE Q1XAB1 Farnesyl pyrophosphate synthase n/a
18 A0A3G3II74_IPE A0A3G3II74 Isopentenyl phosphate kinase n/a
19 Q12051_IPE Q12051 Geranylgeranyl pyrophosphate synthase n/a
20 P62623_IPE P62623 4-hydroxy-3-methylbut-2-enyl diphosphate reductase n/a
21 Q96E22_IPE Q96E22 Dehydrodolichyl diphosphate synthase n/a
22 Q95WL3_IPE Q95WL3 Farnesyl pyrophosphate synthase n/a
23 Q31Q61_IPE Q31Q61 Farnesyl-diphosphate synthase (EC n/a
24 M1JS91_IPE M1JS91 Farnesyl pyrophosphate synthase n/a
25 A0R559_IPE A0R559 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
26 P72683_IPE P72683 Geranylgeranyl pyrophosphate synthase n/a
27 Q60352_IPE Q60352 Isopentenyl phosphate kinase n/a
28 Q16CN9_IPE Q16CN9 Geranyltranstransferase (EC 2.5.1.10) n/a
29 A0A345DF50_IPE A0A345DF50 Butyrophylin 3 n/a