Ligand name: 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE
PDB ligand accession: JAN
DrugBank: DB04960
PubChem: 159324
ChEMBL: CHEMBL289228
InChI Key: PLHJCIYEEKOWNM-HHHXNRCGSA-N
SMILES: Cn1cncc1C(c2ccc(cc2)Cl)(c3ccc4c(c3)C(=CC(=O)N4C)c5cccc(c5)Cl)N

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Phenylpropanoids and polyketides
    • Class: Diarylheptanoids
      • Subclass: Linear diarylheptanoids

List of proteins that are targets for JAN

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	Q02293_JAN	Q02293	n/a
2	P49354_JAN	P49354	modulator	IC50(nM) = 0.9
3	Q4WP27_JAN	Q4WP27	n/a
4	Q4WPS9_JAN	Q4WPS9	n/a
5	P49356_JAN	P49356	modulator	IC50(nM) = 0.86