Ligand name: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
PDB ligand accession: KYN
DrugBank: DB02070
PubChem: 161166;6971029;
ChEMBL: CHEMBL498416
InChI Key: YGPSJZOEDVAXAB-QMMMGPOBSA-N
SMILES: c1ccc(c(c1)C(=O)CC(C(=O)O)N)N

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organic oxygen compounds
    • Class: Organooxygen compounds
      • Subclass: Carbonyl compounds

List of proteins that are targets for KYN

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	Q8N5Z0_KYN	Q8N5Z0	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	n/a
2	Q84HF5_KYN	Q84HF5	Kynurenine 3-monooxygenase (PfKMO)	n/a
3	Q71RI9_KYN	Q71RI9	Kynurenine--oxoglutarate transaminase 3	n/a
4	P05202_KYN	P05202	Aspartate aminotransferase, mitochondrial	n/a
5	O57946_KYN	O57946	Aminotransferase class I/classII	n/a
6	Q8PDA8_KYN	Q8PDA8	Tryptophan 2,3-dioxygenase (TDO)	n/a
7	P14902_KYN	P14902	Indoleamine 2,3-dioxygenase 1	n/a