Ligand name: (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE
PDB ligand accession: L20
DrugBank: DB08073
PubChem: 10172943
ChEMBL: CHEMBL379300
InChI Key: YWTBGJGMTBHQTM-IBGZPJMESA-N
SMILES: Cc1c2cc(ccc2[nH]n1)c3cc(cnc3)OCC(Cc4c[nH]c5c4cccc5)N

ClassyFire chemical classification:

List of proteins that are targets for L20

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P49841_L20 P49841 Glycogen synthase kinase-3 n/a
2 P31751_L20 P31751 RAC-beta serine/threonine-protein kinase n/a IC50(nM) = 0.5
3 P11309_L20 P11309 Serine/threonine-protein kinase pim-1 n/a
4 P17612_L20 P17612 cAMP-dependent protein kinase n/a
5 P00517_L20 P00517 cAMP-dependent protein kinase n/a IC50(nM) = 6.0