Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: METHIONINE
PDB ligand accession: MET
DrugBank: DB00134
PubChem: 6137;6992087;
ChEMBL: CHEMBL42336
InChI Key: FFEARJCKVFRZRR-BYPYZUCNSA-N
SMILES: CSCCC(C(=O)O)N

ClassyFire chemical classification:

List of proteins that are targets for MET

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q9ZCD3_MET Q9ZCD3 Methionine aminopeptidase (MAP) n/a
2 Q9X0Z6_MET Q9X0Z6 [FeFe] hydrogenase maturase n/a
3 P31153_MET P31153 S-adenosylmethionine synthase isoform n/a
4 P56067_MET P56067 Cysteine synthase (CSase) n/a
5 P0CX55_MET P0CX55 Small ribosomal subunit n/a
6 A5U6L5_MET A5U6L5 Methionine aminopeptidase (MAP) n/a
7 P69848_MET P69848 GTP 3',8-cyclase (EC n/a
8 A0A0H3JTG5_MET A0A0H3JTG5 Lipoprotein n/a
9 P80561_MET P80561 Aminopeptidase S (EC n/a
10 P12674_MET P12674 Cysteine synthase A n/a
11 Q58108_MET Q58108 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase n/a
12 P0A817_MET P0A817 S-adenosylmethionine synthase (AdoMet n/a
13 P62081_MET P62081 Small ribosomal subunit n/a
14 Q7BMQ8_MET Q7BMQ8 Lipoprotein n/a
15 Q9HYC7_MET Q9HYC7 Methionine--tRNA ligase (EC n/a
16 Q9BRJ2_MET Q9BRJ2 Large ribosomal subunit n/a
17 Q38C91_MET Q38C91 methionine--tRNA ligase (EC n/a
18 A0A0H0Z019_MET A0A0H0Z019 Methyl-accepting chemotaxis protein n/a
19 K7N5L1_MET K7N5L1 Xaa-Pro Dipeptidase n/a
20 A0A399DY85_MET A0A399DY85 Endoglucanase H (EC n/a
21 P32481_MET P32481 Eukaryotic translation initiation n/a
22 P40217_MET P40217 Eukaryotic translation initiation n/a
23 A7ZPW0_MET A7ZPW0 Dual-specificity RNA methyltransferase n/a
24 F6IQS1_MET F6IQS1 MHC class I n/a
25 A4X3Q0_MET A4X3Q0 Adenosyl-chloride synthase (EC n/a
26 O50008_MET O50008 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 n/a
27 Q8DFC1_MET Q8DFC1 deleted n/a
28 Q9NWU5_MET Q9NWU5 Large ribosomal subunit n/a
29 A0A174NUT3_MET A0A174NUT3 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (EC n/a
30 Q04609_MET Q04609 Glutamate carboxypeptidase 2 n/a
31 P20459_MET P20459 Eukaryotic translation initiation n/a
32 Q9NYK5_MET Q9NYK5 Large ribosomal subunit n/a
33 P28635_MET P28635 D-methionine-binding lipoprotein MetQ n/a
34 P56218_MET P56218 Methionine aminopeptidase (MAP) n/a
35 P00959_MET P00959 Methionine--tRNA ligase (EC n/a
36 B4EA88_MET B4EA88 Lipoprotein n/a
37 P04825_MET P04825 Aminopeptidase N (EC n/a
38 P32929_MET P32929 Cystathionine gamma-lyase (CGL) n/a
39 O15570_MET O15570 Cysteine synthase n/a
40 O31677_MET O31677 7-carboxy-7-deazaguanine synthase (CDG n/a
41 P53582_MET P53582 Methionine aminopeptidase 1 n/a
42 P40969_MET P40969 Centromere DNA-binding protein n/a
43 A0A0F3U9S7_MET A0A0F3U9S7 deleted n/a
44 Q8Z4D7_MET Q8Z4D7 S-ribosylhomocysteine lyase (EC n/a
45 P07906_MET P07906 Methionine aminopeptidase (MAP) n/a
46 D3T7F1_MET D3T7F1 Biotin and thiamin n/a
47 Q9X034_MET Q9X034 5-methylthioadenosine/S-adenosylhomocysteine deaminase (MTA/SAH n/a
48 A7Y7W1_MET A7Y7W1 Periplasmic dipeptide-binding protein n/a
49 P13444_MET P13444 S-adenosylmethionine synthase isoform n/a
50 Q695T7_MET Q695T7 Sodium-dependent neutral amino n/a
51 O67854_MET O67854 Na(+):neurotransmitter symporter (Snf n/a
52 A0A6A5PU90_MET A0A6A5PU90 deleted n/a
53 Q9SKE2_MET Q9SKE2 Jasmonoyl--L-amino acid synthetase n/a
54 Q3MFZ5_MET Q3MFZ5 Amino acid/amide ABC n/a
55 Q4QCD2_MET Q4QCD2 methionine--tRNA ligase (EC n/a
56 Q9RVZ5_MET Q9RVZ5 Aminopeptidase N (EC n/a
57 P9WK91_MET P9WK91 Lipoyl synthase (EC n/a
58 P0ABH9_MET P0ABH9 ATP-dependent Clp protease n/a
59 P60228_MET P60228 Eukaryotic translation initiation n/a
60 Q8ZJ80_MET Q8ZJ80 Methionyl-tRNA formyltransferase (EC n/a
61 O15372_MET O15372 Eukaryotic translation initiation n/a
62 D9N170_MET D9N170 Bifunctional dihydrofolate reductase-thymidylate n/a
63 A0R3E2_MET A0R3E2 Methionine--tRNA ligase (EC n/a
64 Q9JPG4_MET Q9JPG4 Lipoprotein n/a
65 P52286_MET P52286 Suppressor of kinetochore n/a
66 Q83F42_MET Q83F42 Lipoprotein n/a
67 P69905_MET P69905 Hemoglobin subunit alpha n/a
68 P96896_MET P96896 Leucine-responsive regulatory protein n/a
69 Q86D28_MET Q86D28 Methionine gamma-lyase (EC n/a
70 A0A0Z8EWX1_MET A0A0Z8EWX1 Radical SAM n/a
71 F5B6Z0_MET F5B6Z0 Putative prenyl transferase n/a
72 A6ZMK5_MET A6ZMK5 Eukaryotic translation initiation n/a
73 Q5HII6_MET Q5HII6 Methionine--tRNA ligase (EC n/a
74 P44007_MET P44007 S-ribosylhomocysteine lyase (EC n/a
75 Q9ZMW8_MET Q9ZMW8 S-ribosylhomocysteine lyase (EC n/a
76 P00441_MET P00441 Superoxide dismutase [Cu-Zn] n/a
77 P13254_MET P13254 L-methionine gamma-lyase (MGL) n/a
78 Q9RRU8_MET Q9RRU8 S-ribosylhomocysteine lyase (EC n/a
79 Q8CBB9_MET Q8CBB9 S-adenosylmethionine-dependent nucleotide dehydratase n/a
80 Q980A5_MET Q980A5 Translation initiation factor n/a
81 Q9HXY1_MET Q9HXY1 Methionine aminopeptidase (MAP) n/a
82 C6FX51_MET C6FX51 3-methyl-2-indolic acid synthase n/a
83 P82610_MET P82610 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC n/a
84 P07813_MET P07813 Leucine--tRNA ligase (EC n/a
85 P50579_MET P50579 Methionine aminopeptidase 2 product of
86 P17562_MET P17562 S-adenosylmethionine synthase 2 n/a
87 A7AZY4_MET A7AZY4 Lipoprotein n/a
88 Q9C8E7_MET Q9C8E7 Glutamate receptor 3.3 n/a
89 Q9K0L9_MET Q9K0L9 Transcriptional regulator, AsnC n/a
90 Q97Z79_MET Q97Z79 Translation initiation factor n/a
91 Q5W9R9_MET Q5W9R9 Phenylalanine 2-monooxygenase precursor n/a
92 A0A0R1IQH8_MET A0A0R1IQH8 deleted n/a
93 Q70GK9_MET Q70GK9 Fluorinase (EC 2.5.1.63) n/a
94 Q2MFI7_MET Q2MFI7 Putative apramycin biosynthetic n/a
95 P69902_MET P69902 Formyl-CoA:oxalate CoA-transferase (FCOCT) n/a
96 Q5H3Z2_MET Q5H3Z2 Peptide deformylase (PDF) n/a
97 O00303_MET O00303 Eukaryotic translation initiation n/a
98 A0A6A5Q017_MET A0A6A5Q017 deleted n/a
99 A0A059WF38_MET A0A059WF38 DNA-directed RNA polymerase n/a
100 A1HPQ5_MET A1HPQ5 Thiazole biosynthesis protein n/a
101 P0A5J2_MET P0A5J2 Methionine aminopeptidase 2 n/a
102 O07950_MET O07950 Membrane lipoprotein TpN32 n/a
103 A0A0H2UN92_MET A0A0H2UN92 Lipoprotein n/a
104 E9P5T5_MET E9P5T5 Glutamate receptor 1 n/a
105 W0W999_MET W0W999 Fluorinase (EC 2.5.1.63) n/a
106 Q9RQJ2_MET Q9RQJ2 Peptidylarginine deiminase (EC n/a
107 P27635_MET P27635 Large ribosomal subunit n/a
108 Q147X3_MET Q147X3 N-alpha-acetyltransferase 30 (EC n/a
109 Q93YT1_MET Q93YT1 Glutamate receptor 3.2 n/a
110 P0AE18_MET P0AE18 Methionine aminopeptidase (MAP) n/a
111 A0A0D5YKJ7_MET A0A0D5YKJ7 Methionine--tRNA ligase (EC n/a
112 O82392_MET O82392 Phosphomethylpyrimidine synthase, chloroplastic n/a
113 P20042_MET P20042 Eukaryotic translation initiation n/a
114 Q01855_MET Q01855 Small ribosomal subunit n/a
115 P15145_MET P15145 Aminopeptidase N (AP-N) n/a
116 Q8GXJ4_MET Q8GXJ4 Glutamate receptor 3.4 n/a
117 Q8PMP0_MET Q8PMP0 Methionine--tRNA ligase (EC n/a