Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: (4R)-2-METHYLPENTANE-2,4-DIOL
PDB ligand accession: MRD
DrugBank: n/a
PubChem: 5288845
ChEMBL: n/a
InChI Key: SVTBMSDMJJWYQN-RXMQYKEDSA-N
SMILES: CC(CC(C)(C)O)O

ClassyFire chemical classification:

List of proteins that are targets for MRD

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 O74958_MRD O74958 RNA binding exosome n/a
2 Q57193_MRD Q57193 Cholera enterotoxin B-subunit n/a
3 P04084_MRD P04084 Acidic phospholipase A2 n/a
4 D8NA05_MRD D8NA05 deleted n/a
5 A7AH72_MRD A7AH72 deleted n/a
6 Q00511_MRD Q00511 Uricase (EC 1.7.3.3) n/a
7 P24300_MRD P24300 Xylose isomerase (EC n/a
8 P02511_MRD P02511 Alpha-crystallin B chain n/a
9 O67800_MRD O67800 GTPase Era n/a
10 G0RY84_MRD G0RY84 RNA helicase (EC n/a
11 P00431_MRD P00431 Cytochrome c peroxidase, n/a
12 B8HNS6_MRD B8HNS6 hydrogen peroxide-dependent heme n/a
13 B1MIR1_MRD B1MIR1 Dioxygenase n/a
14 Q46RB9_MRD Q46RB9 2-dehydropantoate 2-reductase (EC n/a
15 P48825_MRD P48825 Beta-glucosidase 1 (EC n/a
16 P82597_MRD P82597 Thermostable monoacylglycerol lipase n/a
17 Q6QQE1_MRD Q6QQE1 Cadherin 23 (Cadherin-23 n/a
18 P0ABE7_MRD P0ABE7 Soluble cytochrome b562 n/a
19 Q8GTM0_MRD Q8GTM0 Flower-specific defensin (NaD1) n/a
20 P17811_MRD P17811 Plasminogen activator (Pla) n/a
21 P37821_MRD P37821 1-aminocyclopropane-1-carboxylate synthase (ACC n/a
22 P05132_MRD P05132 cAMP-dependent protein kinase n/a
23 Q98UI8_MRD Q98UI8 Caspase-3 (EC 3.4.22.56) n/a
24 P17734_MRD P17734 Bowman-Birk type seed n/a
25 P21372_MRD P21372 Pre-mRNA-processing ATP-dependent RNA n/a
26 P53041_MRD P53041 Serine/threonine-protein phosphatase 5 n/a
27 P21853_MRD P21853 Periplasmic [NiFe] hydrogenase n/a
28 Q8A905_MRD Q8A905 DUF4038 domain-containing protein n/a
29 Q72IB9_MRD Q72IB9 L-glutamate gamma-semialdehyde dehydrogenase n/a
30 P20440_MRD P20440 Pullulanase secretion protein n/a
31 Q7Y3F3_MRD Q7Y3F3 Endolysin PlyC, small n/a
32 P01074_MRD P01074 Trypsin inhibitor 1 n/a
33 A8Z1E8_MRD A8Z1E8 deleted n/a
34 P14004_MRD P14004 Mite allergen Der n/a
35 A6L3N2_MRD A6L3N2 DUF4038 domain-containing protein n/a
36 Q8CNK1_MRD Q8CNK1 Aminopyrimidine aminohydrolase (EC n/a
37 A0A1L8D0M5_MRD A0A1L8D0M5 Carbon monoxide dehydrogenase n/a
38 A6L4E1_MRD A6L4E1 DUF3826 domain-containing protein n/a
39 Q2YLQ3_MRD Q2YLQ3 Glyoxalase/Bleomycin resistance protein/dioxygenase n/a
40 O27550_MRD O27550 ATP phosphoribosyltransferase (ATP-PRT) n/a
41 P80025_MRD P80025 Lactoperoxidase (LPO) (EC n/a
42 Q180K0_MRD Q180K0 Nitroreductase n/a
43 Q9IW06_MRD Q9IW06 Replicase polyprotein 1ab n/a
44 P53667_MRD P53667 LIM domain kinase n/a
45 P0A7E5_MRD P0A7E5 CTP synthase (EC n/a
46 Q5DL43_MRD Q5DL43 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC n/a
47 P00698_MRD P00698 Lysozyme C (EC n/a
48 D1A7C3_MRD D1A7C3 Formylglycine-generating enzyme (FGE) n/a
49 P40729_MRD P40729 Flagellar biosynthesis protein n/a
50 P51532_MRD P51532 Transcription activator BRG1 n/a
51 P10880_MRD P10880 Shikimate kinase 2 n/a
52 P36979_MRD P36979 Dual-specificity RNA methyltransferase n/a
53 Q9WYL7_MRD Q9WYL7 Bacterioferritin comigratory protein/NADH n/a
54 P00727_MRD P00727 Cytosol aminopeptidase (EC n/a
55 Q9WYP5_MRD Q9WYP5 Myo-inositol 2-dehydrogenase (EC n/a
56 P01903_MRD P01903 HLA class II n/a
57 Q9Y657_MRD Q9Y657 Spindlin-1 (Ovarian cancer-related n/a
58 Q9WXQ8_MRD Q9WXQ8 Ferrous iron transport n/a
59 P01556_MRD P01556 Cholera enterotoxin subunit n/a
60 O73951_MRD O73951 Endo-beta-1,3-glucanase n/a
61 Q97CQ0_MRD Q97CQ0 A-type ATP synthase n/a
62 Q10QA5_MRD Q10QA5 Strigolactone esterase D14 n/a
63 Q3JNW6_MRD Q3JNW6 Catalase-peroxidase (CP) (EC n/a
64 P37078_MRD P37078 Sorbitol operon regulator n/a
65 A0A0F6AK91_MRD A0A0F6AK91 Glycerol-3-phosphate dehydrogenase [NAD(P)+] n/a
66 Q9P8F7_MRD Q9P8F7 triacylglycerol lipase (EC n/a
67 P07221_MRD P07221 Calsequestrin-1 (Aspartactin) (Calsequestrin, n/a
68 A0A493R6T1_MRD A0A493R6T1 Paenibacillus xanthan lyase n/a
69 P00800_MRD P00800 Thermolysin (EC 3.4.24.27) n/a
70 P43183_MRD P43183 Major pollen allergen n/a
71 P00720_MRD P00720 Endolysin (EC 3.2.1.17) n/a
72 O24782_MRD O24782 Cytochrome P450 (Fatty n/a
73 Q02IG8_MRD Q02IG8 deleted n/a
74 Q5S7Y5_MRD Q5S7Y5 Chloroplast triosephosphate isomerase n/a
75 Q9NVD7_MRD Q9NVD7 Alpha-parvin (Actopaxin) (CH-ILKBP) n/a
76 B7ZLF0_MRD B7ZLF0 Fibronectin (FN) (Cold-insoluble n/a
77 A0A0H2YRZ7_MRD A0A0H2YRZ7 Inosine-5'-monophosphate dehydrogenase (IMP n/a
78 C9X208_MRD C9X208 deleted n/a
79 Q8NRS3_MRD Q8NRS3 PorB n/a
80 Q96255_MRD Q96255 Phosphoserine aminotransferase 1, n/a
81 P22629_MRD P22629 Streptavidin n/a
82 A4Q8F7_MRD A4Q8F7 Alpha-N-acetylgalactosaminidase (EC 3.2.1.49) n/a
83 Q60365_MRD Q60365 Riboflavin kinase (RFK) n/a
84 A0A0E2ZNT9_MRD A0A0E2ZNT9 ATP-dependent Clp protease n/a
85 Q13GL4_MRD Q13GL4 Short-chain dehydrogenase/reductase (EC n/a
86 I2DBY1_MRD I2DBY1 Dye-decolorizing peroxidase AauDyP1 n/a
87 A0A0E4G455_MRD A0A0E4G455 Phycoerythrin Beta subunit n/a
88 A4JLJ7_MRD A4JLJ7 Aldehyde dehydrogenase n/a
89 Q97H19_MRD Q97H19 Putative polysaccharide biosynthesis n/a
90 Q5SI02_MRD Q5SI02 L-glutamate gamma-semialdehyde dehydrogenase n/a
91 P01549_MRD P01549 Macromomycin (MCR) (Auromomycin n/a
92 A3DJ38_MRD A3DJ38 Metallophosphoesterase n/a
93 P14420_MRD P14420 Basic phospholipase A2 n/a
94 Q8YA56_MRD Q8YA56 Lmo0305 protein n/a
95 P02917_MRD P02917 Leu/Ile/Val-binding protein (LIV-BP) n/a
96 P00593_MRD P00593 Phospholipase A2 (EC n/a
97 D0VWT6_MRD D0VWT6 Putative antidote protein n/a
98 P01730_MRD P01730 T-cell surface glycoprotein n/a
99 Q9I7C2_MRD Q9I7C2 DNA gyrase subunit n/a
100 P49366_MRD P49366 Deoxyhypusine synthase (DHS) n/a
101 P0A4V4_MRD P0A4V4 Diacylglycerol acyltransferase/mycolyltransferase Ag85C n/a
102 Q1GLD7_MRD Q1GLD7 SnoaL-like domain-containing protein n/a
103 Q5ZRW2_MRD Q5ZRW2 Inorganic pyrophosphatase (EC n/a
104 E3SLL2_MRD E3SLL2 RIIA-RIIB membrane-associated protein n/a
105 Q6TMK4_MRD Q6TMK4 Peroxinectin A (EC n/a
106 Q8YC61_MRD Q8YC61 Acyl-CoA dehydrogenase (EC n/a
107 P27150_MRD P27150 Large ribosomal subunit n/a
108 Q97BK3_MRD Q97BK3 NDP-sugar epimerase n/a
109 Q54A37_MRD Q54A37 Dihydrodiol dehydrogenase n/a
110 Q92I37_MRD Q92I37 Beta sliding clamp n/a
111 Q9X0C3_MRD Q9X0C3 Mannose-1-phosphate guanylyltransferase n/a
112 Q43314_MRD Q43314 Glutamate dehydrogenase 1 n/a
113 O74036_MRD O74036 DNA repair and n/a
114 P00734_MRD P00734 Prothrombin (EC 3.4.21.5) n/a
115 B2J2S4_MRD B2J2S4 Cell wall hydrolase/autolysin n/a
116 Q9KPB6_MRD Q9KPB6 Holo-[acyl-carrier-protein] synthase (Holo-ACP n/a
117 P37001_MRD P37001 Lipid A palmitoyltransferase n/a
118 O59053_MRD O59053 THUMP domain-containing protein n/a
119 Q2F7J3_MRD Q2F7J3 Gag-Pol polyprotein (Pr180gag-pol) n/a
120 Q63IV7_MRD Q63IV7 Cytidine deaminase (EC n/a
121 Q9I2H0_MRD Q9I2H0 DUF4354 family protein n/a
122 O57173_MRD O57173 Apoptosis regulator OPG045 n/a
123 Q9VAK8_MRD Q9VAK8 Protein Diedel n/a
124 Q17ZU8_MRD Q17ZU8 Nitroreductase n/a
125 A0A4Y5PW22_MRD A0A4Y5PW22 Allophycocyanin alpha n/a
126 Q3SAW3_MRD Q3SAW3 Beta-lactamase (EC 3.5.2.6) n/a
127 P16109_MRD P16109 P-selectin (CD62 antigen-like n/a
128 Q976W8_MRD Q976W8 Carboxylesterase (EC 3.1.1.1) n/a
129 A0MK70_MRD A0MK70 Fiber-1 n/a
130 Q389T8_MRD Q389T8 Trypanothione reductase (EC n/a
131 Q0I165_MRD Q0I165 Ribulose-5-phosphate 3-epimerase (EC n/a
132 P46085_MRD P46085 Hemagglutinin components HA-70 n/a
133 P00383_MRD P00383 Dihydrofolate reductase type n/a
134 P0C6Y8_MRD P0C6Y8 Outer capsid protein n/a
135 Q72YY9_MRD Q72YY9 N-acetyltransferase domain-containing protein n/a
136 P14557_MRD P14557 Beta-lactamase SHV-1 (EC n/a
137 B9MKT4_MRD B9MKT4 pectate lyase (EC n/a
138 Q9Y2J8_MRD Q9Y2J8 Protein-arginine deiminase type-2 n/a
139 P42574_MRD P42574 Caspase-3 (CASP-3) (EC n/a
140 Q5L3Y2_MRD Q5L3Y2 Pyridoxal 5'-phosphate synthase n/a
141 P41743_MRD P41743 Protein kinase C n/a
142 P14210_MRD P14210 Hepatocyte growth factor n/a
143 O57947_MRD O57947 Ribose 1,5-bisphosphate isomerase n/a
144 P06737_MRD P06737 Glycogen phosphorylase, liver n/a
145 A0A127ELD1_MRD A0A127ELD1 Inosine-5'-monophosphate dehydrogenase (IMP n/a
146 Q9UYG2_MRD Q9UYG2 ATP-dependent DNA ligase n/a
147 Q9I4X1_MRD Q9I4X1 2-heptyl-4(1H)-quinolone synthase subunit n/a
148 Q8TPV5_MRD Q8TPV5 Flavodoxin n/a
149 P0AE70_MRD P0AE70 Endoribonuclease toxin MazF n/a
150 Q39SD5_MRD Q39SD5 6-phosphogluconate dehydrogenase, decarboxylating n/a
151 B2HVG8_MRD B2HVG8 deleted n/a
152 A4Y4H5_MRD A4Y4H5 SnoaL-like domain-containing protein n/a
153 B7GY71_MRD B7GY71 Diaminopimelate epimerase (DAP n/a
154 U3J0P1_MRD U3J0P1 deleted n/a
155 P0A3R9_MRD P0A3R9 Neocarzinostatin (NCS) (Mitomalcin) n/a
156 A6THE6_MRD A6THE6 Thioredoxin-like protein n/a
157 Q9I5I4_MRD Q9I5I4 Probable enoyl-CoA hydratase/isomerase n/a
158 A9RB27_MRD A9RB27 allene-oxide cyclase (EC n/a
159 Q7SIB6_MRD Q7SIB6 Serine hydroxymethyltransferase (SHMT) n/a
160 P08236_MRD P08236 Beta-glucuronidase (EC 3.2.1.31) n/a
161 Q9X1N9_MRD Q9X1N9 FAD:protein FMN transferase n/a
162 A3F9D6_MRD A3F9D6 Lactoperoxidase (LPO) (EC n/a
163 O25272_MRD O25272 Cag pathogenicity island n/a
164 P31415_MRD P31415 Calsequestrin-1 (Calmitine) (Calsequestrin, n/a
165 I7AL37_MRD I7AL37 Copper oxidase (Laccase n/a
166 A0A2T6C3M6_MRD A0A2T6C3M6 Fucose-binding lectin n/a
167 Q89ZB9_MRD Q89ZB9 pyridoxal kinase (EC n/a
168 Q03555_MRD Q03555 Gephyrin (Putative glycine n/a
169 P0AEJ8_MRD P0AEJ8 Bacterial microcompartment shell n/a
170 Q8TF76_MRD Q8TF76 Serine/threonine-protein kinase haspin n/a
171 Q9UGJ1_MRD Q9UGJ1 Gamma-tubulin complex component n/a
172 A0A0D6J2M1_MRD A0A0D6J2M1 deleted n/a
173 Q884M3_MRD Q884M3 Enoyl-CoA hydratase/isomerase family n/a
174 C0SSE7_MRD C0SSE7 L-fucose isomerase (FucIase) n/a
175 P01887_MRD P01887 Beta-2-microglobulin n/a
176 Q9KL03_MRD Q9KL03 Spermidine N(1)-acetyltransferase (SAT) n/a
177 Q2SWM4_MRD Q2SWM4 Thymidylate kinase (EC n/a
178 B7H2D1_MRD B7H2D1 deleted n/a
179 Q9RSW5_MRD Q9RSW5 DUF3809 domain-containing protein n/a
180 Q2UD26_MRD Q2UD26 Glucose-methanol-choline oxidoreductase N-terminal n/a
181 Q96RI1_MRD Q96RI1 Bile acid receptor n/a
182 O75340_MRD O75340 Programmed cell death n/a
183 Q05JF3_MRD Q05JF3 Calsequestrin n/a
184 P02886_MRD P02886 Discoidin-1 subunit A n/a
185 Q5SID2_MRD Q5SID2 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO (EC n/a
186 Q24451_MRD Q24451 Alpha-mannosidase 2 (EC n/a
187 Q68RJ8_MRD Q68RJ8 lactoylglutathione lyase (EC n/a
188 P42212_MRD P42212 Green fluorescent protein n/a
189 Q9RZH8_MRD Q9RZH8 Uncharacterized protein n/a
190 B0BA40_MRD B0BA40 Enolase (EC 4.2.1.11) n/a
191 B3FRL6_MRD B3FRL6 Extracellular endo-alpha-(1->5)-L-arabinanase 2 n/a
192 O54626_MRD O54626 DotI (IcmL protein) n/a
193 Q8DWV2_MRD Q8DWV2 ClbS/DfsB family four-helix n/a
194 P01375_MRD P01375 Tumor necrosis factor n/a
195 P62993_MRD P62993 Growth factor receptor-bound n/a
196 P63479_MRD P63479 Alanine racemase 1 n/a
197 O07347_MRD O07347 Signal recognition particle n/a
198 T0BV37_MRD T0BV37 deleted n/a
199 P00517_MRD P00517 cAMP-dependent protein kinase n/a
200 P00327_MRD P00327 Alcohol dehydrogenase E n/a
201 Q73WU1_MRD Q73WU1 Glucosyl-3-phosphoglycerate synthase (GpgS) n/a
202 A0AA82WPD8_MRD A0AA82WPD8 Hydroxylamine reductase (EC n/a
203 P21852_MRD P21852 Periplasmic [NiFe] hydrogenase n/a
204 P0C6U8_MRD P0C6U8 Replicase polyprotein 1a n/a
205 P27796_MRD P27796 3-ketoacyl-CoA thiolase, peroxisomal n/a
206 P28871_MRD P28871 Secreted aspartic protease n/a
207 Q72FB2_MRD Q72FB2 Chemotaxis protein CheX, n/a
208 M1EBB2_MRD M1EBB2 Receptor-recognizing protein gp38 n/a
209 E1C9K5_MRD E1C9K5 DNA polymerase I n/a
210 P00644_MRD P00644 Thermonuclease (TNase) (EC n/a
211 P15034_MRD P15034 Xaa-Pro aminopeptidase (EC n/a
212 Q8WSF8_MRD Q8WSF8 Soluble acetylcholine receptor n/a
213 P19909_MRD P19909 Immunoglobulin G-binding protein n/a
214 Q7A6D8_MRD Q7A6D8 deleted n/a
215 Q9LS02_MRD Q9LS02 Allene oxide cyclase n/a
216 P83849_MRD P83849 L-glutamate gamma-semialdehyde dehydrogenase n/a
217 Q9WZL4_MRD Q9WZL4 Flavodoxin-like domain-containing protein n/a
218 P01901_MRD P01901 H-2 class I n/a
219 P22972_MRD P22972 Anti-H(O) lectin 1 n/a
220 P62161_MRD P62161 Calmodulin-2 n/a
221 A0A1W6VP04_MRD A0A1W6VP04 deleted n/a
222 Q81HW2_MRD Q81HW2 Potassium channel protein n/a
223 P0DOX5_MRD P0DOX5 Immunoglobulin gamma-1 heavy n/a
224 Q5F2I3_MRD Q5F2I3 Cytochrome c-552 (EC n/a
225 Q6IBG9_MRD Q6IBG9 Monoglyceride lipase (MGL) n/a
226 J7H5L9_MRD J7H5L9 Glycoprotein n/a
227 A9H5W5_MRD A9H5W5 Nitrogenase protein alpha n/a
228 P21953_MRD P21953 2-oxoisovalerate dehydrogenase subunit n/a
229 Q9LBG2_MRD Q9LBG2 Levodione reductase (EC n/a
230 A6L7K2_MRD A6L7K2 DUF3869 domain-containing protein n/a
231 Q8PXZ6_MRD Q8PXZ6 Methylcobalamin: Coenzyme M n/a
232 P17169_MRD P17169 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] n/a
233 Q4WH08_MRD Q4WH08 Branched-chain amino acid n/a
234 P16083_MRD P16083 Ribosyldihydronicotinamide dehydrogenase [quinone] n/a
235 Q5NH47_MRD Q5NH47 ATP-dependent Clp protease n/a
236 A0A0H3GTN1_MRD A0A0H3GTN1 Betaine aldehyde dehydrogenase n/a
237 Q8VWZ1_MRD Q8VWZ1 Aminoaldehyde dehydrogenase 1, n/a
238 Q6W7J7_MRD Q6W7J7 Beta-glucuronidase (EC 3.2.1.31) n/a
239 B1MHW4_MRD B1MHW4 Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC n/a
240 Q12834_MRD Q12834 Cell division cycle n/a
241 Q9HY79_MRD Q9HY79 Bacterioferritin BfrB (EC n/a
242 O67241_MRD O67241 Flagellar M-ring protein n/a
243 O57728_MRD O57728 A-type ATP synthase n/a
244 A6H6Y4_MRD A6H6Y4 Carboxypeptidase A1 (EC n/a
245 P00766_MRD P00766 Chymotrypsinogen A (EC n/a
246 E7CWP5_MRD E7CWP5 Envelope glycoprotein gp160 n/a
247 Q5FL96_MRD Q5FL96 Myosin-crossreactive antigen n/a
248 O66512_MRD O66512 RNA-binding protein Hfq n/a
249 P0A951_MRD P0A951 Spermidine N(1)-acetyltransferase (SAT) n/a
250 Q8WZ42_MRD Q8WZ42 Titin (EC 2.7.11.1) n/a
251 Q72HW2_MRD Q72HW2 Laccase (EC 1.10.3.2) n/a
252 Q57764_MRD Q57764 Pyruvoyl-dependent arginine decarboxylase n/a
253 P25321_MRD P25321 cAMP-dependent protein kinase n/a
254 C4ZCS9_MRD C4ZCS9 Thoeris protein ThsB n/a
255 P00760_MRD P00760 Serine protease 1 n/a
256 Q4H436_MRD Q4H436 Laccase-like protein n/a
257 A0A0E3W010_MRD A0A0E3W010 Phycoerythrin Alpha subunit n/a
258 D5T7I7_MRD D5T7I7 deleted n/a
259 P20457_MRD P20457 DNA primase large n/a
260 H0USY5_MRD H0USY5 Inorganic pyrophosphatase (EC n/a