Ligand name: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE
PDB ligand accession: NCT
DrugBank: DB00184
PubChem: 89594
ChEMBL: CHEMBL3
InChI Key: SNICXCGAKADSCV-JTQLQIEISA-N
SMILES: CN1CCCC1c2cccnc2

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyridines and derivatives
      • Subclass: Pyrrolidinylpyridines

List of proteins that are targets for NCT

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	P36544_NCT	P36544	Neuronal acetylcholine receptor	agonist	Ki(nM) = 2000.0
2	P00183_NCT	P00183	Camphor 5-monooxygenase (EC	n/a
3	P58154_NCT	P58154	Acetylcholine-binding protein (ACh-binding	n/a	Ki(nM) = 83.0
4	P28329_NCT	P28329	Choline O-acetyltransferase (CHOACTase)	inhibitor
5	P32297_NCT	P32297	Neuronal acetylcholine receptor	agonist	Ki(nM) = 5.0
6	P02714_NCT	P02714	Acetylcholine receptor subunit	n/a
7	P11511_NCT	P11511	Aromatase (EC 1.14.14.14)	inhibitor
8	Q9UGM1_NCT	Q9UGM1	Neuronal acetylcholine receptor	agonist
9	P02710_NCT	P02710	Acetylcholine receptor subunit	n/a
10	P11509_NCT	P11509	Cytochrome P450 2A6	n/a	IC50(nM) = 26300.0
11	F8G0P2_NCT	F8G0P2	Nicotine dehydrogenase (EC	n/a
12	P02718_NCT	P02718	Acetylcholine receptor subunit	n/a
13	Q05901_NCT	Q05901	Neuronal acetylcholine receptor	agonist
14	Q8WSF8_NCT	Q8WSF8	Soluble acetylcholine receptor	n/a
15	Q9GZZ6_NCT	Q9GZZ6	Neuronal acetylcholine receptor	agonist
16	Q15822_NCT	Q15822	Neuronal acetylcholine receptor	agonist	Ki(nM) = 9900.0
17	Q6P988_NCT	Q6P988	Palmitoleoyl-protein carboxylesterase NOTUM	n/a
18	Q16696_NCT	Q16696	Cytochrome P450 2A13	n/a
19	P30926_NCT	P30926	Neuronal acetylcholine receptor	agonist
20	P30532_NCT	P30532	Neuronal acetylcholine receptor	agonist
21	P43681_NCT	P43681	Neuronal acetylcholine receptor	agonist	Ki(nM) = 1.0
22	Q15825_NCT	Q15825	Neuronal acetylcholine receptor	agonist
23	P17787_NCT	P17787	Neuronal acetylcholine receptor	agonist	Ki(nM) = 12.0