Ligand name: (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid
PDB ligand accession: P2E
DrugBank: DB00917
PubChem: 5280360
ChEMBL: CHEMBL548
InChI Key: XEYBRNLFEZDVAW-ARSRFYASSA-N
SMILES: CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Lipids and lipid-like molecules
    • Class: Fatty Acyls
      • Subclass: Eicosanoids

List of proteins that are targets for P2E

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	Q9Y5Y4_P2E	Q9Y5Y4	agonist
2	P34995_P2E	P34995	agonist	Ki(nM) = 9.1 IC50(nM) = 1.1 EC50(nM) = 3.7
3	P43115_P2E	P43115	agonist	Ki(nM) = 0.33 IC50(nM) = 0.94 EC50(nM) = 2.5
4	P35408_P2E	P35408	agonist	Ki(nM) = 0.11 IC50(nM) = 0.55 EC50(nM) = 0.02
5	P43116_P2E	P43116	agonist	Ki(nM) = 1.0 IC50(nM) = 2.6 EC50(nM) = 1.9