Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: PHOSPHOENOLPYRUVATE
PDB ligand accession: PEP
DrugBank: DB01819
PubChem: 1005;58114173;59658623;
ChEMBL: CHEMBL1235228
InChI Key: DTBNBXWJWCWCIK-UHFFFAOYSA-N
SMILES: C=C(C(=O)O)OP(=O)(O)O

ClassyFire chemical classification:

List of proteins that are targets for PEP

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P07379_PEP P07379 Phosphoenolpyruvate carboxykinase, cytosolic n/a Ki(nM) = 289000.0
2 Q8U0A9_PEP Q8U0A9 2-dehydro-3-deoxyphosphoheptonate aldolase (EC n/a
3 P00939_PEP P00939 Triosephosphate isomerase (TIM) n/a
4 P00886_PEP P00886 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive n/a
5 B7MLA0_PEP B7MLA0 Enolase (EC 4.2.1.11) n/a
6 Q9WYH8_PEP Q9WYH8 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
7 Q96X30_PEP Q96X30 Enolase (EC 4.2.1.11) n/a
8 P9WNL1_PEP P9WNL1 Enolase (EC 4.2.1.11) n/a
9 P0A715_PEP P0A715 2-dehydro-3-deoxyphosphooctonate aldolase (EC n/a
10 P22221_PEP P22221 Pyruvate, phosphate dikinase, n/a
11 P30615_PEP P30615 Pyruvate kinase 1 n/a
12 Q8DQ84_PEP Q8DQ84 Pyruvate kinase (EC n/a
13 O69174_PEP O69174 Enolase (EC 4.2.1.11) n/a
14 A9WCM4_PEP A9WCM4 Enolase (EC 4.2.1.11) n/a
15 Q3JP68_PEP Q3JP68 2-dehydro-3-deoxyphosphooctonate aldolase (EC n/a
16 Q83E11_PEP Q83E11 3-phosphoshikimate 1-carboxyvinyltransferase (EC n/a
17 P32449_PEP P32449 Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited n/a
18 A0A0E8NV14_PEP A0A0E8NV14 Enolase (EC 4.2.1.11) n/a
19 P9WP83_PEP P9WP83 Phosphoenolpyruvate guanylyltransferase (PEP n/a
20 P13035_PEP P13035 Aerobic glycerol-3-phosphate dehydrogenase n/a
21 P30613_PEP P30613 Pyruvate kinase PKLR n/a
22 P56060_PEP P56060 2-dehydro-3-deoxyphosphooctonate aldolase (EC n/a
23 P0A993_PEP P0A993 Fructose-1,6-bisphosphatase class 1 n/a
24 Q8NNL5_PEP Q8NNL5 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
25 P22487_PEP P22487 3-phosphoshikimate 1-carboxyvinyltransferase (EC n/a
26 P00512_PEP P00512 ATP-dependent 6-phosphofructokinase (ATP-PFK) n/a
27 P0AB91_PEP P0AB91 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive n/a
28 Q38BV6_PEP Q38BV6 phosphopyruvate hydratase (EC n/a
29 P09104_PEP P09104 Gamma-enolase (EC 4.2.1.11) n/a
30 Q6R2Q7_PEP Q6R2Q7 Xylulose-5-phosphate/fructose-6-phosphate phosphoketolase (EC n/a
31 Q9K169_PEP Q9K169 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
32 O66496_PEP O66496 2-dehydro-3-deoxyphosphooctonate aldolase (EC n/a
33 Q8Y6T2_PEP Q8Y6T2 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase n/a
34 Q42736_PEP Q42736 Pyruvate, phosphate dikinase, n/a
35 P21642_PEP P21642 Phosphoenolpyruvate carboxykinase [GTP], n/a
36 A5TYT6_PEP A5TYT6 Phosphoenolpyruvate carboxykinase [GTP] n/a
37 Q16875_PEP Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase n/a
38 Q57265_PEP Q57265 Capsule biosynthesis protein n/a
39 Q9YEJ7_PEP Q9YEJ7 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
40 P00924_PEP P00924 Enolase 1 (EC n/a
41 Q8R7R4_PEP Q8R7R4 Phosphoenolpyruvate-protein phosphotransferase (EC n/a
42 O53512_PEP O53512 Phospho-2-dehydro-3-deoxyheptonate aldolase AroG n/a
43 Q31QJ8_PEP Q31QJ8 Enolase (EC 4.2.1.11) n/a
44 P35558_PEP P35558 Phosphoenolpyruvate carboxykinase, cytosolic n/a
45 P11155_PEP P11155 Pyruvate, phosphate dikinase n/a
46 G3XCJ9_PEP G3XCJ9 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
47 Q9JZ55_PEP Q9JZ55 2-dehydro-3-deoxyphosphooctonate aldolase (EC n/a
48 Q9I000_PEP Q9I000 Phospho-2-dehydro-3-deoxyheptonate aldolase (EC n/a
49 P13929_PEP P13929 Beta-enolase (EC 4.2.1.11) n/a