Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 4'-PHOSPHOPANTETHEINE
PDB ligand accession: PNS
DrugBank: DB03912
PubChem: 115254
ChEMBL: n/a
InChI Key: JDMUPRLRUUMCTL-VIFPVBQESA-N
SMILES: CC(C)(COP(=O)(O)O)C(C(=O)NCCC(=O)NCCS)O

ClassyFire chemical classification:

List of proteins that are targets for PNS

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 A0R0B3_PNS A0R0B3 Meromycolate extension acyl n/a
2 P23875_PNS P23875 Phosphopantetheine adenylyltransferase (EC n/a
3 Q88Z44_PNS Q88Z44 Holo-[acyl-carrier-protein] synthase (Holo-ACP n/a
4 B7H2D0_PNS B7H2D0 deleted n/a
5 Q88VM8_PNS Q88VM8 D-alanyl carrier protein n/a
6 F2K077_PNS F2K077 Butyryl-CoA dehydrogenase (EC n/a
7 P0C062_PNS P0C062 Gramicidin S synthase n/a
8 P0A530_PNS P0A530 Phosphopantetheine adenylyltransferase (EC n/a
9 P34731_PNS P34731 Fatty acid synthase n/a
10 Q03132_PNS Q03132 Erythronolide synthase EryA2 n/a
11 E9JES6_PNS E9JES6 CcbZ (Putative dehydrogenase/acyl n/a
12 B7MJ81_PNS B7MJ81 Acyl carrier protein n/a
13 A4PHM4_PNS A4PHM4 Hybrid non ribosomal n/a
14 Q76KY5_PNS Q76KY5 [acyl-carrier-protein] S-malonyltransferase (EC n/a
15 Q4KCZ1_PNS Q4KCZ1 Peptidyl carrier protein n/a
16 Q6DNF2_PNS Q6DNF2 CurA n/a
17 Q02054_PNS Q02054 Actinorhodin polyketide synthase n/a
18 P10378_PNS P10378 Enterobactin synthase component n/a
19 Q47NR9_PNS Q47NR9 Non-ribosomal peptide synthase:Amino n/a
20 Q5W265_PNS Q5W265 Probable acyl carrier n/a
21 L0R8F8_PNS L0R8F8 Mitochondrial ribosome and n/a
22 O77077_PNS O77077 Acyl carrier protein n/a
23 P0A6A8_PNS P0A6A8 Acyl carrier protein n/a
24 P43098_PNS P43098 Fatty acid synthase n/a
25 A0A140KF01_PNS A0A140KF01 Fatty acid synthase n/a
26 Q5EDC8_PNS Q5EDC8 Acyl carrier protein n/a
27 Q12053_PNS Q12053 Norsolorinic acid synthase n/a
28 P24224_PNS P24224 Holo-[acyl-carrier-protein] synthase (Holo-ACP n/a
29 P07854_PNS P07854 Acyl carrier protein n/a
30 O14561_PNS O14561 Acyl carrier protein, n/a
31 Q39T60_PNS Q39T60 Acyl carrier protein n/a
32 F1CWE4_PNS F1CWE4 TqaA n/a
33 P07149_PNS P07149 Fatty acid synthase n/a
34 F2K074_PNS F2K074 Alpha/beta hydrolase fold n/a
35 Q76KY4_PNS Q76KY4 Acyl-carrier-protein n/a
36 Q70LM7_PNS Q70LM7 Linear gramicidin synthase n/a
37 Q5G940_PNS Q5G940 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ n/a
38 A4PHN0_PNS A4PHN0 Hybrid polyketide synthase-non n/a
39 I7FMV0_PNS I7FMV0 Polyketide synthase PKS13 n/a
40 A4PHM7_PNS A4PHM7 Enoyl-CoA hydratase n/a
41 W5NQT7_PNS W5NQT7 Acyl carrier protein n/a
42 Q82SY3_PNS Q82SY3 Carrier domain-containing protein n/a
43 P19097_PNS P19097 Fatty acid synthase n/a
44 H1ZZT7_PNS H1ZZT7 Type I modular n/a
45 A9CHM9_PNS A9CHM9 Aminoacyl carrier protein n/a
46 P28037_PNS P28037 Cytosolic 10-formyltetrahydrofolate dehydrogenase n/a
47 Q89VT8_PNS Q89VT8 Amino acid--[acyl-carrier-protein] ligase n/a
48 E5XP76_PNS E5XP76 Carboxylic acid reductase n/a
49 A0A806GVW0_PNS A0A806GVW0 deleted n/a
50 A0A6D2XA84_PNS A0A6D2XA84 deleted n/a
51 W5PGA3_PNS W5PGA3 deleted n/a
52 Q9WZK0_PNS Q9WZK0 Phosphopantetheine adenylyltransferase (EC n/a
53 G7RM21_PNS G7RM21 deleted n/a
54 Q89VT6_PNS Q89VT6 Aminoacyl carrier protein n/a
55 A0A5H1ZR44_PNS A0A5H1ZR44 holo-ObiF1 n/a
56 E9AD06_PNS E9AD06 Acyl carrier protein n/a
57 P39579_PNS P39579 D-alanyl carrier protein n/a
58 P21645_PNS P21645 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (UDP-3-O-(3-OHC14)-GlcN n/a
59 F4Y432_PNS F4Y432 CurD (Hydroxymethylglutaryl-CoA synthase n/a
60 Q5SJS9_PNS Q5SJS9 Phosphopantetheine adenylyltransferase (EC n/a
61 Q6DNF1_PNS Q6DNF1 CurB n/a
62 Q6N882_PNS Q6N882 Acyl carrier protein n/a
63 B1MDL6_PNS B1MDL6 Phosphopantetheine adenylyltransferase (EC n/a