Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose
PDB ligand accession: PRP
DrugBank: DB01632
PubChem: 7339
ChEMBL: n/a
InChI Key: PQGCEDQWHSBAJP-TXICZTDVSA-N
SMILES: C(C1C(C(C(O1)OP(=O)(O)OP(=O)(O)O)O)O)OP(=O)(O)O

ClassyFire chemical classification:

List of proteins that are targets for PRP

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q26997_PRP Q26997 Hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGPRT) n/a
2 Q4FQF7_PRP Q4FQF7 ATP phosphoribosyltransferase (ATP-PRT) n/a
3 A5U4M0_PRP A5U4M0 Anthranilate phosphoribosyltransferase (EC n/a
4 P9WFX5_PRP P9WFX5 Anthranilate phosphoribosyltransferase (EC n/a
5 Q81WF6_PRP Q81WF6 Orotate phosphoribosyltransferase (OPRT) n/a
6 P43490_PRP P43490 Nicotinamide phosphoribosyltransferase (NAmPRTase) n/a
7 Q980Q4_PRP Q980Q4 Uracil phosphoribosyltransferase (EC n/a
8 P60891_PRP P60891 Ribose-phosphate pyrophosphokinase 1 n/a
9 Q9NWZ5_PRP Q9NWZ5 Uridine-cytidine kinase-like 1 n/a
10 P9WHK9_PRP P9WHK9 Orotate phosphoribosyltransferase (OPRT) n/a
11 P08870_PRP P08870 Orotate phosphoribosyltransferase (OPRT) substrate
12 P43619_PRP P43619 Nicotinate-nucleotide pyrophosphorylase [carboxylating] n/a
13 A0A5S9CYM0_PRP A0A5S9CYM0 Beta-ribofuranosylaminobenzene 5'-phosphate synthase n/a
14 Q967M2_PRP Q967M2 adenine phosphoribosyltransferase (EC n/a
15 P50384_PRP P50384 Anthranilate phosphoribosyltransferase (EC n/a
16 A0A1S0QLD4_PRP A0A1S0QLD4 deleted n/a
17 Q66DQ2_PRP Q66DQ2 Adenine phosphoribosyltransferase (APRT) n/a
18 Q26998_PRP Q26998 Uracil phosphoribosyltransferase (UPRT) n/a
19 C3LU29_PRP C3LU29 ATP phosphoribosyltransferase (ATP-PRT) n/a
20 P13298_PRP P13298 Orotate phosphoribosyltransferase 1 n/a
21 D0KMY9_PRP D0KMY9 Phosphoribosyltransferase n/a
22 Q5HSJ4_PRP Q5HSJ4 ATP phosphoribosyltransferase (ATP-PRT) n/a
23 Q27796_PRP Q27796 Hypoxanthine phosphoribosyltransferase (EC n/a
24 P07741_PRP P07741 Adenine phosphoribosyltransferase (APRT) n/a
25 P66992_PRP P66992 Anthranilate phosphoribosyltransferase (EC n/a
26 P07285_PRP P07285 Anthranilate phosphoribosyltransferase (PRtransferase) n/a
27 Q02129_PRP Q02129 ATP phosphoribosyltransferase (ATP-PRT) n/a
28 P00492_PRP P00492 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) n/a
29 Q8VP84_PRP Q8VP84 Anthranilate phosphoribosyltransferase (EC n/a