Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: 3,5,7,3',4'-PENTAHYDROXYFLAVONE
PDB ligand accession: QUE
DrugBank: DB04216
PubChem: 5280343
ChEMBL: CHEMBL50
InChI Key: REFJWTPEDVJJIY-UHFFFAOYSA-N
SMILES: c1cc(c(cc1C2=C(C(=O)c3c(cc(cc3O2)O)O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for QUE

# DrugDomain Data UniProt Accession Drug Action Affinity data
1 P16083_QUE P16083 inhibitor
2 Q8NFU5_QUE Q8NFU5 n/a IC50(nM) = 2300.0
3 P02766_QUE P02766 n/a
4 O02697_QUE O02697 n/a
5 P80457_QUE P80457 n/a Ki(nM) = 1200.0
IC50(nM) = 31900.0
6 Q9LNE6_QUE Q9LNE6 n/a
7 A2VA43_QUE A2VA43 n/a
8 O68183_QUE O68183 n/a
9 P68400_QUE P68400 n/a Ki(nM) = 1180.0
10 O00303_QUE O00303 n/a
11 Q6VT83_QUE Q6VT83 n/a
12 P07900_QUE P07900 n/a
13 O94768_QUE O94768 n/a
14 P06576_QUE P06576 n/a
15 Q15393_QUE Q15393 n/a
16 Q16678_QUE Q16678 n/a Ki(nM) = 23.0
IC50(nM) = 77.0
EC50(nM) = 1100.0
17 E9NWK5_QUE E9NWK5 n/a
18 P00829_QUE P00829 n/a
19 P60709_QUE P60709 n/a
20 P08631_QUE P08631 n/a
21 Q9Y230_QUE Q9Y230 n/a
22 P53355_QUE P53355 n/a IC50(nM) = 8900.0
23 P0DTC1_QUE P0DTC1 n/a
24 Q9AIU0_QUE Q9AIU0 n/a
25 O22304_QUE O22304 n/a
26 P05631_QUE P05631 n/a
27 P11309_QUE P11309 n/a IC50(nM) = 43.0
Kd(nM) = 25.0
28 P67870_QUE P67870 n/a
29 P36542_QUE P36542 n/a
30 O75469_QUE O75469 activator
31 Q96323_QUE Q96323 n/a
32 P32361_QUE P32361 n/a
33 P19483_QUE P19483 n/a
34 P00749_QUE P00749 n/a IC50(nM) = 12100.0
35 P93799_QUE P93799 n/a
36 Q8N6T7_QUE Q8N6T7 n/a IC50(nM) = 1900.0
EC50(nM) = 990000.0
37 P22314_QUE P22314 n/a
38 P03372_QUE P03372 n/a
39 P35869_QUE P35869 n/a
40 P40947_QUE P40947 n/a
41 P48736_QUE P48736 n/a IC50(nM) = 3800.0
Kd(nM) = 280.0
42 P46422_QUE P46422 n/a
43 P25705_QUE P25705 n/a
44 Q8IXJ6_QUE Q8IXJ6 n/a
45 P00489_QUE P00489 n/a
46 Q6NVY1_QUE Q6NVY1 n/a
47 Q92731_QUE Q92731 n/a
48 Q6NUS8_QUE Q6NUS8 n/a
49 Q7SIC2_QUE Q7SIC2 n/a
50 Q5G940_QUE Q5G940 n/a
51 P04278_QUE P04278 n/a
52 P54652_QUE P54652 n/a
53 P16152_QUE P16152 n/a