Ligand name: PROGESTERONE
PDB ligand accession: STR
DrugBank: DB00396
PubChem: 5994
ChEMBL: CHEMBL103
InChI Key: RJKFOVLPORLFTN-LEKSSAKUSA-N
SMILES: CC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Lipids and lipid-like molecules
    • Class: Steroids and steroid derivatives
      • Subclass: Pregnane steroids

List of proteins that are targets for STR

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	P05090_STR	P05090	n/a
2	A9FDB7_STR	A9FDB7	n/a
3	A7U483_STR	A7U483	n/a
4	P02701_STR	P02701	n/a
5	P06401_STR	P06401	agonist	Ki(nM) = 3.4 IC50(nM) = 0.2 EC50(nM) = 0.1
6	P71278_STR	P71278	n/a
7	P51857_STR	P51857	n/a
8	P08235_STR	P08235	antagonist	IC50(nM) = 14.0 Kd(nM) = 0.39
9	P01011_STR	P01011	n/a
10	P10275_STR	P10275	agonist	Ki(nM) = 8.5 IC50(nM) = 14.0
11	Q04828_STR	Q04828	n/a
12	P52895_STR	P52895	n/a
13	P08185_STR	P08185	n/a	Ki(nM) = 42.0
14	P41145_STR	P41145	activator
15	P04278_STR	P04278	binder	Kd(nM) = 115.0
16	P04150_STR	P04150	partial agonist	Ki(nM) = 30.5 IC50(nM) = 1000.0
17	D6N9X1_STR	D6N9X1	n/a
18	Q16874_STR	Q16874	n/a
19	P02763_STR	P02763	binder
20	P01868_STR	P01868	n/a
21	Q5YNS8_STR	Q5YNS8	n/a
22	P03372_STR	P03372	agonist	IC50(nM) = 1000.0
23	P08684_STR	P08684	n/a
24	Q92731_STR	Q92731	agonist
25	P05093_STR	P05093	substrate