Ligand name: 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine
PDB ligand accession: TAK
DrugBank: DB08597
PubChem: 11524144
ChEMBL: CHEMBL478629
InChI Key: XHBVYDAKJHETMP-UHFFFAOYSA-N
SMILES: c1cc(ccc1c2cnc3c(cnn3c2)c4ccncc4)OCCN5CCCCC5

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyrazolopyrimidines
      • Subclass: Pyrazolo[1,5-a]pyrimidines

List of proteins that are targets for TAK

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	Q14680_TAK	Q14680	Maternal embryonic leucine	n/a
2	P27037_TAK	P27037	Activin receptor type-2A	n/a
3	P54646_TAK	P54646	5'-AMP-activated protein kinase	n/a
4	P62942_TAK	P62942	Peptidyl-prolyl cis-trans isomerase	n/a
5	Q13131_TAK	Q13131	5'-AMP-activated protein kinase	inhibitor
6	Q04771_TAK	Q04771	Activin receptor type-1	n/a	IC50(nM) = 68.0